How to replace lamotrigine with valproate

Epilepsia

Volumn 47, Issue 11, 2006, Pages 1943-1944

  Steinhoff, Bernhard J ^a,b  

^a Epilepsiezentrum Kork   (Germany)

^b EPILEPSIEZENTRUM KORK   (Germany)

Author keywords

Lamotrigine; Monotherapy; Switch; Valproate

Indexed keywords

ETHOSUXIMIDE; LAMOTRIGINE; VALPROIC ACID;

ADULT; ARTICLE; ATAXIA; BLURRED VISION; CASE REPORT; DISEASE FREE INTERVAL; DIZZINESS; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DOSE REDUCTION; DRUG DOSE REGIMEN; DRUG INDUCED HEADACHE; DRUG SUBSTITUTION; DRUG TOLERABILITY; FATIGUE; FEMALE; FOLLOW UP; HUMAN; MAINTENANCE DRUG DOSE; MONOTHERAPY; NAUSEA; OUTCOME ASSESSMENT; PATIENT COMPLIANCE; PATIENT SATISFACTION; PRIORITY JOURNAL; SEIZURE; TONIC CLONIC SEIZURE; TREMOR; VERTIGO; VOMITING;

ADOLESCENT; ADULT; ANTICONVULSANTS; COST-BENEFIT ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; EPILEPSY; FEMALE; HUMANS; TREATMENT OUTCOME; TRIAZINES; VALPROIC ACID;

EID: 33750924274     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2006.00832.x     Document Type: Article

References (9)

1. Begey GK. (2005) Evidence-based treatment of idiopathic generalized epilepsies with new antiepleptic drugs. Epilpesia 46(suppl 9):161-168.
2. Faught E, Morris G, Jacobson M, French J, Harden C, Montouris G, Rosenfeld W. (1999) Adding lamotrigine to valproate: incidence of rash and other adverse effects. Postmarketing Antiepileptic Drug Survey (PADS) Group. Epilepsia 40:1135-1140.
3. Morris GL, Hammer AE, Kustra RP, Messenheimer JA. (2004) Lamotrigine for patients with juvenile myoclonic epilepsy following prior treatment with valproate: results of an open-label study. Epilepsy Behavior 5:509-512.
4. Morrow J, Russell A, Guthrie E, Parsons L, Robertson I, Waddell R, Irwin B, McGivern RC, Morrison PJ, Craig J. (2006) Malformation risks of antiepileptic drugs in pregnancy: a prospective study from the UK Epilepsy and Pregnancy Register. Journal of Neurology, Neurosurgery and Psychiatry 77:193-198.
5. Nicolson A, Appleton RE, Chadwick DW, Smith DF. (2004) The relationship between treatment with valproate, lamotrigine, and topiramate and the prognosis of the idiopathic generalised epilepsies. Journal of Neurology, Neurosurgery and Psychiatry 75:75-79.
6. Perucca E. (2006) Clinically relevant drug interactions with antiepileptic drugs. British Journal of Clinical Pharmacology 61:246-255.
7. Pisani F, Oteri G, Russo MF, Di Perri R, Perucca E, Richens A. (1999) The efficacy of valproate-lamotrigine comedication in refractory complex-partial seizures: evidence for a pharmacodynamic interaction. Epilepsia 40:1141-1146.
8. Prasad A, Kuzniecky RI, Knowlton RC, Welty TE, Martin RC, Mendez M, Faught RE. (2004) Evolving antiepileptic drug treatment in juvenile myoclonic epilepsy. Archives of Neurology 61:1100-1105.
9. Tomson T. (2004) Drug selection for the newly diagnosed patient: when is a new generation antiepileptic drug indicated? Journal of Neurology 251:1043-1049.