Suicidality in depressive children and adolescents during treatment with selective serotonin reuptake inhibitors: Review and meta-analysis of the available randomised, placebo controlled trials;Suizidalität bei depressiven kindern und jugendlichen unter behandlung mit selektiven serotoninwiederaufnahmehemmern: Review und metaanalyse verfügbarer plazebokontrollierter doppelblindstudien

Nervenarzt

Volumn 77, Issue 11, 2006, Pages 1332-1337

  Holtmann, M ^a   Bolte S ^a   Poustka, F ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

Adolescents; Children; Depression; Selective serotonin reuptake inhibitors; Suicidality

Indexed keywords

FLUOXETINE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE;

ARTICLE; CLINICAL TRIAL; DEPRESSION; DISEASE ASSOCIATION; DRUG EFFECT; DRUG EFFICACY; EVIDENCE BASED PRACTICE; HUMAN; META ANALYSIS; RISK ASSESSMENT; SUICIDAL IDEATION; SYSTEMATIC REVIEW; TREATMENT INDICATION;

ADOLESCENT; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; CHILD; CHILD, PRESCHOOL; DEPRESSION; FEMALE; HUMANS; INCIDENCE; MALE; PLACEBO EFFECT; RANDOMIZED CONTROLLED TRIALS; RISK ASSESSMENT; RISK FACTORS; SEROTONIN UPTAKE INHIBITORS; SUICIDE, ATTEMPTED;

EID: 33750909123     PISSN: 00282804     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00115-005-1952-3     Document Type: Article

References (30)

1. Andrews JA, Lewinsohn PM (1992) Suicidal attempts among older adolescents: prevalence and co-occurrence with psychiatric disorders. J Am Acad Child Adolesc Psychiatry 31:655-662
2. Arzneimittelkommission der deutschen Ärzteschaft (2004) SSRI und Suizidalität? Dtsch Arztebl 101:A2642 [Heft 39]. Langfassung verfügbar unter: http://www.aerzteblatt.de/plus3904
3. Benkert O, Hippius H (2003) Kompendium der Psychiatrischen Pharmakotherapie, 4. Aufl. Springer, Berlin Heidelberg New York
4. Brent DA, Birmaher B (2004) British warnings on SSRI questioned. J Am Acad Child Adolesc Psychiatry 43:379-380
5. Costello EJ, Angold A, Burns BJ et al. (1996) The great smoky mountains study of youth. Goals, design, methods, and the prevalence of DSM-III-R disorders. Arch Gen Psychiatry 53:1129-1136
6. CSM (2004) Selective Serotonin Reuptake Inhibitors (SSRIs) - overview of regulatory status and CSM advice relating to major depressive disorder (MDD) in children and adolescents: summary of clinical trials. Verfügbar unter: http://www.mca.gov.uk/ourwork/monitorsafequalmed/safetymessages/ ssrioverview_101203.htm. Zugriff am 15. April 2005
7. DGKJP (2003) Leitlinien zur Diagnostik und Therapie von psychischen Störungen im Säuglings-, Kindes- und Jugendalter. Deutscher Ärzte Verlag, Köln
8. Fegert JM, Herpertz-Dahlmann B (2004) Zur Problematik der Gabe von Selektiven Serotoninwiederaufnahmehemmern (SSRI) bei depressiven Kindern und Jugendlichen. Nervenarzt 75:908-910
9. Emslie GJ, Heiligenstein JH, Wagner KD et al. (2002) Fluoxetine for acute treatment of depression in children and adolescents: a placebo-controlled, randomized clinical trial. J Am Acad Child Adolesc Psychiatry 41:1205-1215
10. Emslie GJ, Rush AJ, Weinberg WA et al. (1997) A double-blind, randomized, placebo-controlled trial of fluoxetine in children and adolescents with depression. Arch Gen Psychiatry 54:1031-1037
11. FDA (2004) Review and evaluation of clinical data. Verfügbar unter: http://www.fda.gov/ohrms/dockets/ac/04/briefing/2004-4065b1-10-TAB08-Hammads- Review.pdf. Zugriff am 15. April 2005
12. Fergusson DM, Lynskey MT (1995) Childhood circumstances, adolescent adjustment, and suicide attempts in a New Zealand birth cohort. J Am Acad Child Adolesc Psychiatry 34:612-622
13. Fleiss JL (1981) Statistical methods for rates and proportions. Wiley, New York
14. Goodwin FK, Fireman B, Simon GE et al. (2003) Suicide risk in bipolar disorder during treatment with lithium and divalproex. JAMA 290:1467-1473
15. Hazell P, O'Connell D, Heathcote D et al. (2003) Tricyclic drugs for depression in children and adolescents. The Cochrane Library, Issue 3
16. Holtmann M, Bölte S, Wöckel L et al. (2005) Antidepressive Therapie bei Kindern und Jugendlichen: Anwendung und Stellenwert der Selektiven Serotonin-Wiederaufnahmehemmer. Dtsch Arztebl 102:976-978
17. Isacsson G, Holmgren P, Ahlner J (2005) Selective serotonin reuptake inhibitor antidepressants and the risk of suicide: a controlled forensic database study of 14,857 suicides. Acta Psychiatr Scand 111:286-290
18. Jobson KO, Potter WZ (1995) International Psychopharmacology Algorithm Project Report. Psychopharmacol Bull 31:457-507
19. Keller MB, Ryan ND, Strober M et al. (2001) Efficacy of paroxetine in the treatment of adolescent major depression: a randomized, controlled trial. J Am Acad Child Adolesc Psychiatry 40:762-772
20. Kenny DA (1999) Meta-Analysis. Version II. University of Connecticut
21. King RA, Riddle MA, Chappell PB et al. (1991) Emergence of self-destructive phenomena in children and adolescents during fluoxetine treatment. J Am Acad Child Adolesc Psychiatry 30:179-186
22. Mandoki MW, Tapia MR, Tapia MA et al. (1997) Venlafaxine in the treatment of children and adolescents with major depression. Psychopharmacol Bull 33:149-154
23. March J, Silva S, Petrycki S et al. (2004) Fluoxetine, cognitive-behavioral therapy, and their combination for adolescents with depression: treatment for adolescents with depression study (TADS) randomized controlled trial. JAMA 292:807-820
24. Martinez C, Rietbrock S, Wise L et al. (2005) Antidepressant treatment and the risk of fatal and nonfatal self harm in first episode depression: nested case-control study. BMJ 330:389-395
25. Myers K, McCauley E, Calderon R et al. (1991) Risks for suicidality in major depressive disorder. J Am Acad Child Adolesc Psychiatry 30:86-94
26. Olfson M, Shaffer D, Marcus SC et al. (2003) Relationship between antidepressant medication treatment and suicide in adolescents. Arch Gen Psychiatry 60:978-982
27. Simeon JG, Dinicola VF, Ferguson HB et al. (1990) Adolescent depression: a placebo-controlled fluoxetine treatment study and follow-up. Prog Neuropsychopharmacol Biol Psychiatry 14:791-795
28. Vitiello B, Swedo S (2004) Antidepressant medications in children. N Engl J Med 350:1489-1491
29. Wagner KD, Ambrosini P, Rynn M et al. (2003) Sertraline Pediatric Depression Study Group. Efficacy of sertraline in the treatment of children and adolescents with major depressive disorder: two randomized controlled trials. JAMA 290:1033-1041
30. Whittington CJ, Kendall T, Fonagy P et al. (2004) Selective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data. Lancet 363:1341-1345