Grid-based molecular modeling for pharmaceutical salt screening: Case example of 3,4,6,7,8,9-hexahydro-2H-pyrimido (1,2-a) pyrimidinium acetate

Journal of Pharmaceutical Sciences

Volumn 95, Issue 11, 2006, Pages 2361-2372

  Hammond, Robert B ^a   Hashim, Rose S ^a   Ma, Caiyun ^a   Roberts, Kevin J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

3,4,6,7,8,9 hexahydro 2H pyrimido (1,2 a) pyrimidinium acetate; Co crystals; Crystal structure; Crystallography; Drug design; Molecular modeling; Molecular simulations; Salt selection; Solid dosage form; Systematic search

Indexed keywords

3,4,6,7,8,9 HEXAHYDRO 2H PYRIMIDO (1,2 A) PYRIMIDINIUM ACETATE; PYRIMIDINE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CRYSTAL; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY;

EID: 33750904749     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20657     Document Type: Article

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