Adenosine restores angiotensin II-induced contractions by receptor-independent enhancement of calcium sensitivity in renal arterioles

Circulation Research

Volumn 99, Issue 10, 2006, Pages 1117-1124

  Lai, En Yin ^a   Martinka, Peter ^b   Fähling, Michael ^b   Mrowka, Ralf ^b   Steege, Andreas ^b,c   Gericke, Adrian ^b   Sendeski, Mauricio ^b   Persson, P B ^b   Persson, A Erik G ^a   Patzak, Andreas ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Adenosine; Afferent arterioles; Angiotensin II; Calcium sensitivity; Desensitization; Kidney; Myosin light chain

Indexed keywords

ADENOSINE; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR; CALCIUM; MITOGEN ACTIVATED PROTEIN KINASE P38; MYOSIN LIGHT CHAIN; PROTEIN KINASE C; RHO KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; BLOOD VESSEL TONE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CONTROLLED STUDY; DESENSITIZATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; HYPOXIA; JUXTAGLOMERULAR APPARATUS; KIDNEY BLOOD FLOW; KIDNEY ISCHEMIA; KIDNEY VASCULAR RESISTANCE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR INTRINSIC ACTIVITY; RENAL ARTERY; SMOOTH MUSCLE FIBER;

ADENOSINE; ADENOSINE TRIPHOSPHATE; ANGIOTENSIN II; ANIMALS; ARTERIOLES; CALCIUM; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOTONIC CONTRACTION; KIDNEY; MALE; MICE; MICE, INBRED C57BL; MYOSIN LIGHT CHAINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; POTASSIUM CHLORIDE; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, PURINERGIC P1;

EID: 33750897558     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000249530.85542.d4     Document Type: Article

References (44)

1. Hansen PB, Hashimoto S, Briggs J, Schnermann J. Attenuated renovascular constrictor responses to angiotensin II in adenosine 1 receptor knockout mice. Am J Physiol Regul Integr Comp Physiol. 2003;285:R44-R49.
2. Osswald H, Schmitz HJ, Heidenreich O. Adenosine response of the rat kidney after saline loading, sodium restriction and hemorrhagia. Pflugers Arch. 1975;357:323-333.
3. Weihprecht H, Lorenz JN, Briggs JP, Schnermann J. Synergistic effects of angiotensin and adenosine in the renal microvasculature. Am J Physiol. 1994;266:F227-F239.
4. Hall JE, Granger JP, Hester RL. Interactions between adenosine and angiotensin II in controlling glomerular filtration. Am J Physiol. 1985;248:F340-F346.
5. Lai EY, Patzak A, Steege A, Mrowka R, Brown R, Spielmann N, Persson PB, Fredholm BB, Persson AE. Contribution of adenosine receptors in the control of arteriolar tone and adenosine-angiotensin II interaction. Kidney Int. 2006;70:690-698.
6. Arendshorst WJ, Brannstrom K, Ruan X Actions of angiotensin II on the renal microvasculature. J Am Soc Nephrol. 1999;10(suppl 11):S149-S161.
7. Hansen PB, Schnermann J. Vasoconstrictor and vasodilator effects of adenosine in the kidney. Am J Physiol Renal Physiol. 2003;285:F590-F599.
8. Freedman NJ, Lefkowitz RJ. Desensitization of G protein-coupled receptors. Recent Prog Horm Res. 1996;51:319-351.
9. Kornfeld M, Gutierrez AM, Persson AE, Salomonsson M. Angiotensin II induces a tachyphylactic calcium response in the rabbit afferent arteriole. Acta Physiol Scand. 1997;160:165-173.
10. Bohm SK, Khitin LM, Grady EF, Aponte G, Payan DG, Bunnett NW. Mechanisms of desensitization and resensitization of proteinase-activated receptor-2. J Biol Chem. 1996;271:22003-22016.
11. Casey PJ. Protein lipidation in cell signaling. Science. 1995;268:221-225.
12. Rubin LJ, Johnson LR, Dodam JR, Dhalla AK, Magliola L, Laughlin MH, Jones AW. Selective transport of adenosine into porcine coronary smooth muscle. Am J Physiol Heart Circ Physiol. 2000;279:H1397-H1410.
13. Patzak A, Lai EY, Mrowka R, Steege A, Persson PB, Persson AEG. AT1 receptors mediate angiotensin II induced release of nitric oxide in afferent arterioles. Kidney Int. 2004;66:1949-1958.
14. Chaudhari A, Kirschenbaum MA. A rapid method for isolating rabbit renal microvessels. Am J Physiol. 1988;254:F291-F296.
15. Brackett LE, Daly JW. Relaxant effects of adenosine analogs on guinea pig trachea in vitro: xanthine-sensitive and xanthine-insensitive mechanisms. J Pharmacol Exp Ther. 1991;257:205-213.
16. Liu R, Gutierrez AM, Ring A, Persson AE. Nitric oxide induces resensitization of P2Y nucleotide receptors in cultured rat mesangial cells. J Am Soc Nephrol. 2002;13:313-321.
17. Ganitkevich V, Hasse V, Pfitzer G. Ca2+-dependent and Ca2+-independent regulation of smooth muscle contraction. J Muscle Res Cell Motil. 2002;23:47-52.
18. Somlyo AP, Somlyo AV. Signal transduction and regulation in smooth muscle. Nature. 1994;372:231-236.
19. Somlyo AP, Somlyo AV Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II. J Physiol. 2000;522(pt 2):177-185.
20. Feng J, Ito M, Ichikawa K, Isaka N, Nishikawa M, Hartshorne DJ, Nakano T. Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase. J Biol Chem. 1999;274:37385-37390.
21. Eto M, Ohmori T, Suzuki M, Furuya K, Morita F. A novel protein phosphatase-1 inhibitory protein potentiated by protein kinase C. Isolation from porcine aorta media and characterization. J Biochem (Tokyo). 1995;118:1104-1107.
22. Kitazawa T, Takizawa N, Ikebe M, Eto M Reconstitution of protein kinase C-induced contractile Ca2+ sensitization in triton X-100-demembranated rabbit arterial smooth muscle. J Physiol. 1999;520(pt 1):139-152.
23. Meloche S, Landry J, Huot J, Houle F, Marceau F, Giasson E. p38 MAP kinase pathway regulates angiotensin II-induced contraction of rat vascular smooth muscle. Am J Physiol Heart Circ Physiol. 2000;279:H741-H751.
24. Kim B, Kim J, Bae YM, Cho SI, Kwon SC, Jung JY, Park JC, Ahn HY. p38 mitogen-activated protein kinase contributes to the diminished aortic contraction by endothelin-1 in DOCA-salt hypertensive rats. Hypertension. 2004;43:1086-1091.
25. Kwon S, Lee WJ, Fang LH, Kim B, Ahn HY. Mitogen-activated protein kinases partially regulate endothelin-1-induced contractions through a myosin light chain phosphorylation-independent pathway. J Vet Med Sci. 2003;65:225-230.
26. Kyriakis JM, Avruch J. Sounding the alarm: protein kinase cascades activated by stress and inflammation. J Biol Chem. 1996;271:24313-24316.
27. Irwin DC, Tissot van Patot MC, Tucker A, Bowen R. Direct ANP inhibition of hypoxia-induced inflammatory pathways in pulmonary microvascular and macrovascular endothelial monolayers. Am J Physiol Lung Cell Mol Physiol. 2005;288:L849-L859.
28. Martin JL, Avkiran M, Quinlan RA, Cohen P, Marber MS. Antiischemic effects of SB203580 are mediated through the inhibition of p38alpha mitogen-activated protein kinase. Evidence from ectopic expression of an inhibition-resistant kinase. Circ Res. 2001;89:750-752.
29. Jackson EK, Dubey RK. Role of the extracellular cAMP-adenosine pathway in renal physiology. Am J Physiol Renal Physiol. 2001;281:F597-F612.
30. de la Haba G, Cantoni GL. The enzymatic synthesis of S-adenosyl-L- homocysteine from adenosine and homocysteine. J Biol Chem. 1959;234:603-608.
31. Kloor D, Ludtke A, Stoeva S, Osswald H. Adenosine binding sites at S-adenosylhomocysteine hydrolase are controlled by the NAD+/NADH ratio of the enzyme. Biochem Pharmacol. 2003;66:2117-2123.
32. ten Hove M, Lygate CA, Fischer A, Schneider JE, Sang AE, Hulbert K, Sebag-Montefiore L, Watkins H, Clarke K, Isbrandt D, Wallis J, Neubauer S. Reduced inotropic reserve and increased susceptibility to cardiac ischemia/reperfusion injury in phosphocreatine-deficient guanidinoacetate-N- methyltransferase-knockout mice. Circulation. 2005;111:2477-2485.
33. Londos C, Wolff J. Two distinct adenosine-sensitive sites on adenylate cyclase. Proc Natl Acad Sci U S A. 1977;74:5482-5486.
34. Tesmer JJ, Dessauer CW, Sunahara RK, Murray LD, Johnson RA, Gilman AG, Sprang SR. Molecular basis for P-site inhibition of adenylyl cyclase. Biochemistry. 2000;39:14464-14471.
35. Kloor D, Delabar U, Muhlbauer B, Luippold G, Osswald H. Tissue levels of S-adenosylhomocysteine in the rat kidney: effects of ischemia and homocysteine. Biochem Pharmacol. 2002;63:809-815.
36. Takeuchi T, Kitayama M, Kushida M, Fujita A, Hata F. Essential role of ATP synthesized by creatine kinase in contraction of alpha-toxin permeabilized preparations of tonic type smooth muscle. J Pharmacol Sci. 2003;92:374-380.
37. Lofgren M, Malmqvist U, Arner A. Substrate and product dependence of force and shortening in fast and slow smooth muscle. J Gen Physiol. 2001;117:407-418.
38. Osswald H, Hermes HH, Nabakowski G. Role of adenosine in signal transmission of tubuloglomerular feedback. Kidney Int Suppl. 1982;12:S136-S142.
39. Brown R, Ollerstam A, Johansson B, Skott O, Gebre-Medhin S, Fredholm B, Persson AE. Abolished tubuloglomerular feedback and increased plasma renin in adenosine A(1) receptor-deficient mice. Am J Physiol Regul Integr Comp Physiol. 2001;281:R1362-R1367.
40. Sun D, Samuelson LC, Yang T, Huang Y, Paliege A, Saunders T, Briggs J, Schnermann J. Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors. Proc Natl Acad Sci U S A. 2001;98:9983-9988.
41. Bell PD, Lapointe JY, Sabirov R, Hayashi S, Peti-Peterdi J, Manabe K, Kovacs G, Okada Y. Macula densa cell signaling involves ATP release through a maxi anion channel. Proc Natl Acad Sci U S A. 2003;100:4322-4327.
42. Castrop H, Huang Y, Hashimoto S, Mizel D, Hansen P, Theilig F, Bachmann S, Deng C, Briggs J, Schnermann J. Impairment of tubuloglomerular feedback regulation of GFR in ecto-5′-nucleotidase/CD73-deficient mice. J Clin Invest. 2004;114:634-642.
43. Thomson S, Bao D, Deng A, Vallon V. Adenosine formed by 5′-nucleotidase mediates tubuloglomerular feedback. J Clin Invest. 2000;106:289-298.
44. Baranowski RL, Westenfelder C. Estimation of renal interstitial adenosine and purine metabolites by microdialysis. Am J Physiol. 1994;267:F174-F182.