A superfusion system to study border zones in confluent cultures of neonatal rat heart cells

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 274, Issue 6 43-6, 1998, Pages

  Hyatt, Christopher J ^a   Lemasters, John J ^b   Muller Borer, Barbara J ^a   Johnson, Timothy A ^a   Cascio, Wayne E ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Arrhythmia; Gap junctions; Intracellular pH; Ischemia; Monolayer

Indexed keywords

ANIMAL CELL; ARTICLE; CELL COMMUNICATION; CELL PH; FLUORESCENCE MICROSCOPY; GAP JUNCTION; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 33750880053     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1998.274.6.h2001     Document Type: Article

References (22)

1. Berlin, J. R., M. B. Cannell, and W. J. Lederer. Cellular origins of the transient inward current in cardiac myocytes: role of fluctuations and waves of elevated intracellular calcium. Circ. Res. 65:115-126,1989.
2. Berne, R. M., and M. N. Levy. Physiology (2nd ed.). St. Louis, MO: Mosby, 1988.
3. 2+ homeostasis in the pH paradox of reperfusion injury to neonatal rat cardiac myocytes. Am. J. Physiol. 265 (Cell Physiol. 34): C129-C137,1993.
4. Cascio, W. E., G. X. Yan, and A. G. Kleber. Early changes in extracellular potassium in ischemic rabbit myocardium: the role of extracellular carbon dioxide accumulation and diffusion. Circ. Res. 70:409-422,1992.
5. 2+, and volume inside cultured adult rabbit cardiac myocytes during chemical hypoxia: a multiparameter digitized confocal microscopic study. Biophys. J. 66: 942-952, 1994.
6. 2+, intercellular electrical coupling and mechanical activity in ischemic rabbit papillary muscle: effects of preconditioning and metabolic blockade. Circ. Res. 79:237-246,1996.
7. Fast, V. G., and A. G. Kléber. Microscopic conduction in cultured strands of neonatal rat heart cells measured with voltage-sensitive dyes. Circ. Res. 73:914-925,1993.
8. Fast, V. G., and A. G. Kléber. Anisotropic conduction in monolayers of neonatal rat heart cells cultured on collagen substrate. Circ. Res. 75:591-595,1994.
9. Hofmann, H. Interaction between a noRmoxic and a hypoxic region of guinea pig and ferret papillary muscles. Circ. Res. 56: 876-883,1985.
10. Janse, M. J., J. Cinca, H. Morena, J. W. T. Fiolet, A. G. Kléber, G. P. de Vries, A. Becker, and D. Durrer. The "border zone" in myocardial ischemia. Circ. Res. 44:576-588,1979.
11. Janse, M. J., H. Morena, J. Cinca, J. W. T. Fiolet, W. J. G. Krieger, and D. Durrer. Electrophysiological, metabolic and morphological aspects of acute myocardial ischemia in the iso-lated porcine heart: characterization of the "border zone." J. Physiol. (Paris) 76: 785-790,1980.
12. 2+ fluctuation in cultured neonatal rat cardiac myocytesby heptanol. Erp. Cell Res. 220:348-356,1995.
13. Koslow, A. R., R. R. Stromberg, L; I. Friedman, R. J. Lutz, S. L. Hubert, and P. Schuster. A flow system for the study of shear forces upon cultured endothelial cells. J. Biomech. Eng. 108:338-341,1986.
14. Kundu, P. K. Fluid Mechanics. San Diego, CA: Academic, 1990.
15. Rohr, S., and B. M. Salzberg. Characterization of impulse propagation at the microscopic level across geometrically defined expansions of excitable tissue: multiple site optical recording of transmembrane voltage (MSORTV) in patterned growth heart cell cultures. J. Gen. Physiol. 104: 287-309,1994.
16. Rohr, S., and B. M. Salzberg. Multiple site optical recording of transmembrane voltage (MSORTV) in patterned growth heart cell cultures: assessing electrical behavior, with microsecond resolution, on a cellular and subcellular scale. Biophys. J. 67: 1301-1315,1994.
17. Rohr, S., D. M. Scholly, and A. G. Kleber. Patterned growth of neonatal rat heart cells in culture: morphological and electrophysiological characterization. Circ. Res. 68:114-130,1991.
18. Thandroyen, F. T., A. C. Morris, H. K. Hagler, B. Ziman, L. Pai, J. T. Willerson, and L. M. Buja. Intracellular calcium transients and arrhythmia in isolated heart cells. Circ. Res. 69: 810-819,1991.
19. Viggers, R. F., A. R. Wechezak, and L. R. Sauvage. An apparatus to study the response of cultured endothelium to shear stress. J. Biomech. Eng. 108:332-337,1986.
20. Wilensky, R. L., J. Tranum-Jensen, R. Coronel, A. A. M. Wilde, J. W. T. Fiolet, and M. J. Janse. The subendocardial border zone during acute ischemia of the rabbit heart: an electrophysiologic, metabolic, and morphologic correlative study. Circulation 74:1137-1146,1986.
21. Wit, A. L., and M. J. Janse. The Ventricular Arrhythmias of Ischemia and Infarction: Electrophysiological Mechanisms. Mount Kisco, NY: Futura, 1993.
22. Yamada, K. A., J. McHowat, G. X. Yan, K. Donahue, J. Peirick, A. G. Kleber, and P. B. Corr. Cellular uncoupling induced by accumulation of long-chain acylcarnitine during ischemia. Circ. Res. 74: 83-95,1994.