Unscheduled CDK1 activity in G1 phase of the cell cycle triggers apoptosis in X-irradiated lymphocytic leukemia cells

Cellular and Molecular Life Sciences

Volumn 63, Issue 21, 2006, Pages 2538-2545

  Wu, J ^a   Feng, Y ^a   Xie, D ^a   Li, X ^a   Xiao, W ^a   Tao, D ^a   Qin, J ^a   Hu, J ^a   Gardner, K ^b   Judge, S I V ^c   Li, Q Q ^b   Gong, J ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; CDK1; CDK2; Cyclin B1; G1 arrest; Lymphocytic leukemia cells; MOLT 4 cells; X irradiation

Indexed keywords

CYCLIN B1; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE INHIBITOR 1; ROSCOVITINE; THREONINE; TYROSINE;

APOPTOSIS; ARTICLE; CANCER RADIOTHERAPY; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL DEATH; CELL LYSATE; CELL SELECTION; CELLULAR DISTRIBUTION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IONIZING RADIATION; LEUKEMIA CELL; LYMPHATIC LEUKEMIA; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; X IRRADIATION;

APOPTOSIS; CDC2 PROTEIN KINASE; CYCLIN B; CYCLIN-DEPENDENT KINASE 2; G1 PHASE; HUMANS; LEUKEMIA, LYMPHOCYTIC; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR CELLS, CULTURED; X-RAYS;

EID: 33750851669     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-006-6138-z     Document Type: Article

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