Endogenous nitric oxide buffers blood pressure variability between 0.2 and 0.6 Hz in the conscious rat

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 272, Issue 2 41-2, 1997, Pages

  Nafz, Benno ^a   Wagner, Claus D ^a   Persson, Pontus B ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

conscious animal experiments; endothelium; fast Fourier transform; sex differences; spectral analysis

Indexed keywords

N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; BLOOD PRESSURE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; FEMALE; HEART RATE; MALE; NONHUMAN; PRIORITY JOURNAL; SEX DIFFERENCE; SHEAR STRESS;

EID: 33750849536     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1997.272.2.h632     Document Type: Article

References (28)

1. Akselrod, S., S. Eliash, O. Oz, and S. Cohen. Hemodynamic regulation in SHR: investigation by spectral analysis. Am. J. Physiol. 253 (Heart Circ. Physiol. 22): H176-H183, 1987.
2. Beierwaltes, W. H., D'A. L. Potter, O. A. Carretero, and D. H. Sigmon. Nitric oxide synthesis inhibition blocks reversal of two-kidney, one clip renovascular hypertension after unclipping. Hypertension Dallas 25: 174-179, 1995.
3. Cerutti, C., M. P. Gustin, C. Z. Paultre, M. Lo, C. Julien, M. Vincent, and J. Sassard. Autonomic nervous system and cardiovascular variability in rats: a spectral analysis approach. Am. J. Physiol. 261 (Heart Circ. Physiol. 30): H1292-H1299, 1991.
4. ω-monomethyl-L-arginine on short-term RR interval and systolic blood pressure oscillations. J. Cardiovasc. Pharmacol. 24: 323-327, 1994.
5. Gonzalez, C., C. Martin, E. Hamel, E. Galea, B. Gomez, S. Lluch, and C. Estrada. Endothelial cells inhibit the vascular response to adrenergic nerve stimulation by a receptor-mediated mechanism. Can. J. Physiol. Pharmacol. 68: 104-109, 1990.
6. Griffith, T. M., D. H. Edwards, R. L. Davies, T. J. Harrison, and K. T. Evans. EDRF coordinates the behaviour of vascular resistance vessels. Nature Lond. 329: 442-445, 1987.
7. Hayashi, T., J. M. Fukuto, L. J. Ignarro, and G. Chaudhuri. Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis. Proc. Natl. Acad. Sci. USA 89: 11259-11263, 1992.
8. Harada, S., S. Tokunaga, M. Momohara, H. Masaki, T. Tagawa, T. Imaizumi, and A. Takeshita. Inhibition of nitric oxide formation in the nucleus tractus solitarius increases renal sympathetic nerve activity in rabbits. Circ. Res. 72: 511-516, 1993.
9. Huang, B. S., and F. H. Leenen. Dietary Na and baroreflex modulation of blood pressure and RSNA in normotensive vs. spontaneously hypertensive rats. Am. J. Physiol. 266 (Heart Circ. Physiol. 35): H496-H502, 1994.
10. Huang, P. L., Z. Huang, H. Mashimo, K. D. Bloch, M. A. Moskowitz, J. A. Bevan, and M. C. Fishman. Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature Lond. 377: 239-242, 1995.
11. Janssen, B. J., J. Oosting, D. W. Slaaf, P. B. Persson, and H. A. Struijker Boudier. Hemodynamic basis of oscillations in systemic arterial pressure in conscious rats. Am. J. Physiol. 269 (Heart Circ. Physiol. 38): H62-H71, 1995.
12. Japundzic, N., M. L. Grichois, P. Zitoun, D. Laude, and J. L. Elghozi. Spectral analysis of blood pressure and heart rate in conscious rats: effects of autonomic blockers. J. Auton. Nerv. Syst. 30: 91-100, 1990.
13. Julien, C., Z.-Q. Zhang, C. Cerutti, and C. Barres. Hemodynamic analysis of arterial pressure oscillations in conscious rats. J. Auton. Nerv. Syst. 50: 239-252, 1995.
14. Just, A., U. Wittmann, B. Nafz, C. D. Wagner, H. Ehmke, H. R. Kirchheim, and P. B. Persson. The blood pressure buffering capacity of nitric oxide by comparison to the baroreflex. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H521-H527, 1994.
15. Knowles, R. G., and S. Moncada. Nitric oxide as a signal in blood vessels. Trends Biochem. Sci. 17: 399-402, 1992.
16. Lowenstein, C. J., and S. H. Snyder. Nitric oxide, a novel biologic messenger. Cell 70: 705-707, 1992.
17. Michel, T., and S. Lamas. Molecular cloning of constitutive endothelial nitric oxide synthase: evidence for a family of related genes. J. Cardiovasc. Pharmacol. 20, Suppl. 12: S45-S49, 1992.
18. Miller, V. M., and J. C. J. Burnett. Modulation of NO and endothelin by chronic increases in blood flow in canine femoral arteries. Am. J. Physiol. 263 (Heart Circ. Physiol. 32): H103-H108, 1992.
19. Persson, P. B. Modulation of cardiovascular control mechanisms and their interaction. Physiol. Rev. 76: 193-243, 1996.
20. Persson, P. B., J. E. Baumann, H. Ehmke, B. Nafz, U. Wittmann, and H. R. Kirchheim. Phasic and 24-h blood pressure control by endothelium-derived relaxing factor in conscious dogs. Am. J. Physiol. 262 (Heart Circ. Physiol. 31): H1395-H1400, 1992.
21. Ranjan, V., Z. Xiao, and S. L. Diamond. Constitutive NOS expression in cultured endothelial cells is elevated by fluid shear stress. Am. J. Physiol. 269 (Heart Circ. Physiol. 38): H550-H555, 1995.
22. Rees, D. D., R. M. J. Palmer, and S. Moncada. Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc. Natl. Acad. Sci. USA 86: 3375-3378, 1989.
23. Romero, J. C., V. Lahera, M. G. Salom, and M. L. Biondi. Role of the endothelium-dependent relaxing factor nitric oxide on renal function. J. Am. Soc. Nephrol. 2: 1371-1387, 1992.
24. Rubanyi, G. M., A. D. Freay, K. Kauser, A. Johns, and D. R. Harder. Mechanoreception by the endothelium: mediators and mechanisms of pressure- and flow-induced vascular responses. Blood Vessels 27: 246-257, 1990.
25. G-methyl-L-arginine, an inhibitor of L-arginine-derived nitric oxide synthesis, stimulates renal sympathetic nerve activity in vivo. A role for nitric oxide in the central regulation of sympathetic tone. Circ. Res. 70: 607-611, 1992.
26. Salom, M. G., V. Lahera, and J. C. Romero. Role of prostaglandins and endothelium-derived relaxing factor on the renal response to acetylcholine. Am. J. Physiol. 260 (Renal Fluid Electrolyte Physiol. 29): F145-F149, 1991.
27. Scheffer, G. J., B. J. TenVoorde, J. M. Karemaker, and H. H. Ros. Effects of epidural analgesia and atropine on heart rate and blood pressure variability: implications for the interpretation of beat-to-beat fluctuations. Eur. J. Anaesthesiol. 11: 75-80, 1994.
28. Zanzinger, J., J. Czachurski, and H. Seller. Inhibition of sympathetic vasoconstriction is a major principle of vasodilation by nitric oxide in vivo. Circ. Res. 75: 1073-1077, 1994.