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Volumn 7, Issue 4, 2006, Pages 315-320

Evidence-based neoadjuvant endocrine therapy for breast cancer

Author keywords

Aromatase inhibitors; Hormonal treatment; Predictive markers; Preoperative therapy; Surrogate markers; Tamoxifen

Indexed keywords

ANASTROZOLE; AROMATASE INHIBITOR; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; EVEROLIMUS; EXEMESTANE; GEFITINIB; KI 67 ANTIGEN; LETROZOLE; PACLITAXEL; PLACEBO; PROGESTERONE RECEPTOR; TAMOXIFEN;

EID: 33750847913     PISSN: 15268209     EISSN: None     Source Type: Journal    
DOI: 10.3816/CBC.2006.n.043     Document Type: Review
Times cited : (2)

References (55)
  • 1
    • 50549123220 scopus 로고
    • On the treatment of inoperable cases of carcinoma of the mamma: Suggestions for a new method of treatment, with illustrative cases
    • Beatson GT. On the treatment of inoperable cases of carcinoma of the mamma: suggestions for a new method of treatment, with illustrative cases. Lancet 1896; 2:104-107.
    • (1896) Lancet , vol.2 , pp. 104-107
    • Beatson, G.T.1
  • 2
    • 12244294506 scopus 로고    scopus 로고
    • Tamoxifen alone versus adjuvant tamoxifen for operable breast cancer of the elderly: Long-term results of the phase III randomized controlled multicenter GRETA trial
    • Mustacchi G, Ceccherini R, Milani S, et al. Tamoxifen alone versus adjuvant tamoxifen for operable breast cancer of the elderly: long-term results of the phase III randomized controlled multicenter GRETA trial. Ann Oncol 2003; 14:414-420.
    • (2003) Ann Oncol , vol.14 , pp. 414-420
    • Mustacchi, G.1    Ceccherini, R.2    Milani, S.3
  • 3
    • 0025869592 scopus 로고
    • Breast cancer in elderly women: A Cancer Research Campaign trial comparing treatment with tamoxifen and optimal surgery with tamoxifen alone
    • Bates T, Riley DL, Houghton J, et al. Breast cancer in elderly women: a Cancer Research Campaign trial comparing treatment with tamoxifen and optimal surgery with tamoxifen alone. Br J Surg 1991; 78:591-594.
    • (1991) Br J Surg , vol.78 , pp. 591-594
    • Bates, T.1    Riley, D.L.2    Houghton, J.3
  • 4
    • 2942579073 scopus 로고    scopus 로고
    • Late follow-up of a randomized trial of surgery plus tamoxifen versus tamoxifen alone in women aged over 70 years with operable breast cancer
    • Fennessy M, Bates T, MacRae K, et al. Late follow-up of a randomized trial of surgery plus tamoxifen versus tamoxifen alone in women aged over 70 years with operable breast cancer. Br J Surg 2004; 91:699-704.
    • (2004) Br J Surg , vol.91 , pp. 699-704
    • Fennessy, M.1    Bates, T.2    MacRae, K.3
  • 5
    • 0642347622 scopus 로고    scopus 로고
    • The effect on tumor response of adding sequential preoperative docetaxel to preoperative doxorubicin and cyclophosphamide: Preliminary results from the National Surgical Adjuvant Breast and Bowel Project protocol B-27
    • Bear HD, Anderson S, Brown A, et al. The effect on tumor response of adding sequential preoperative docetaxel to preoperative doxorubicin and cyclophosphamide: preliminary results from the National Surgical Adjuvant Breast and Bowel Project protocol B-27. J Clin Oncol 2003; 21:4165-4174.
    • (2003) J Clin Oncol , vol.21 , pp. 4165-4174
    • Bear, H.D.1    Anderson, S.2    Brown, A.3
  • 6
    • 0035751675 scopus 로고    scopus 로고
    • Preoperative chemotherapy in patients with operable breast cancer: Nine-year results from National Surgical Adjuvant Breast and Bowel Project protocol B-18
    • Wolmark N, Wang J, Mamounas E, et al. Preoperative chemotherapy in patients with operable breast cancer: nine-year results from National Surgical Adjuvant Breast and Bowel Project protocol B-18. J Natl Cancer Inst 2001; 30:96-102.
    • (2001) J Natl Cancer Inst , vol.30 , pp. 96-102
    • Wolmark, N.1    Wang, J.2    Mamounas, E.3
  • 7
    • 0346600381 scopus 로고    scopus 로고
    • Preoperative systemic treatment: Prediction of responsiveness
    • Colleoni M, Zahrieh D, Gelber RD, et al. Preoperative systemic treatment: prediction of responsiveness. Breast 2003; 12:538-542.
    • (2003) Breast , vol.12 , pp. 538-542
    • Colleoni, M.1    Zahrieh, D.2    Gelber, R.D.3
  • 8
    • 3042677083 scopus 로고    scopus 로고
    • Pathological complete response to chemotherapy is related to hormone receptor status
    • (Abstract #302)
    • Buzdar AU, Valero V, Theriault RL, et al. Pathological complete response to chemotherapy is related to hormone receptor status. Breast Cancer Res Treat 2003; 82(suppl 1):s69 (Abstract #302).
    • (2003) Breast Cancer Res Treat , vol.82 , Issue.SUPPL. 1
    • Buzdar, A.U.1    Valero, V.2    Theriault, R.L.3
  • 9
    • 0142231212 scopus 로고    scopus 로고
    • Negative steroid receptors are a good predictor for response to preoperative chemotherapy in breast cancer - Results of a randomized trial
    • (Abstract #35)
    • Untch M, Kahlert V, Moebus C, et al. Negative steroid receptors are a good predictor for response to preoperative chemotherapy in breast cancer - results of a randomized trial. Proc Am Soc Clin Oncol 2003; 22:9 (Abstract #35).
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 9
    • Untch, M.1    Kahlert, V.2    Moebus, C.3
  • 11
    • 0020061006 scopus 로고
    • Tamoxifen as initial sole treatment of localized breast cancer in elderly women: A pilot study
    • Preece PE, Wood RA, Nackie CR, et al. Tamoxifen as initial sole treatment of localized breast cancer in elderly women: a pilot study. Br Med J 1982; 284:869-870.
    • (1982) Br Med J , vol.284 , pp. 869-870
    • Preece, P.E.1    Wood, R.A.2    Nackie, C.R.3
  • 12
    • 0019940246 scopus 로고
    • Treatment of early localized breast cancer in elderly patients by tamoxifen
    • Hellberg A, Lundgren B, Norin T, et al. Treatment of early localized breast cancer in elderly patients by tamoxifen. Br J Radiol 1982; 55:511-515.
    • (1982) Br J Radiol , vol.55 , pp. 511-515
    • Hellberg, A.1    Lundgren, B.2    Norin, T.3
  • 13
    • 0020587406 scopus 로고
    • Primary treatment of breast cancer in elderly women with tamoxifen
    • Bradbeer JW, Kyngdon J. Primary treatment of breast cancer in elderly women with tamoxifen. Clin Oncol 1983; 9:31-34.
    • (1983) Clin Oncol , vol.9 , pp. 31-34
    • Bradbeer, J.W.1    Kyngdon, J.2
  • 14
    • 0006861761 scopus 로고
    • Tamoxifen as primary treatment of breast cancer in elderly or frail patients: A practical management
    • Allan SG, Rodger A, Smyth JF, et al. Tamoxifen as primary treatment of breast cancer in elderly or frail patients: a practical management. Br Med J 1985; 290:358.
    • (1985) Br Med J , vol.290 , pp. 358
    • Allan, S.G.1    Rodger, A.2    Smyth, J.F.3
  • 15
    • 0021671715 scopus 로고
    • The management of locally advanced carcinoma of the breast by Novaldex (tamoxifen): A pilot study
    • Campbell FC, Morgan DA, Bishop HM, et al. The management of locally advanced carcinoma of the breast by Novaldex (tamoxifen): a pilot study. Clin Oncol 1984; 10: 111-115.
    • (1984) Clin Oncol , vol.10 , pp. 111-115
    • Campbell, F.C.1    Morgan, D.A.2    Bishop, H.M.3
  • 16
    • 0024596891 scopus 로고
    • Tamoxifen as an alternative to surgical resection for selected geriatric patients with primary breast cancer
    • Margolese RG, Foster RS. Tamoxifen as an alternative to surgical resection for selected geriatric patients with primary breast cancer. Arch Surg 1989; 124:548-550.
    • (1989) Arch Surg , vol.124 , pp. 548-550
    • Margolese, R.G.1    Foster, R.S.2
  • 17
    • 0026020406 scopus 로고
    • A 10-year experience of tamoxifen as primary treatment of breast cancer in 100 elderly and frail patients
    • Akhtar SS, Allan SE, Rodger A, et al. A 10-year experience of tamoxifen as primary treatment of breast cancer in 100 elderly and frail patients. Eur J Surg Oncol 1991; 17:30-35.
    • (1991) Eur J Surg Oncol , vol.17 , pp. 30-35
    • Akhtar, S.S.1    Allan, S.E.2    Rodger, A.3
  • 18
    • 13844258497 scopus 로고
    • Tamoxifen as sole therapy for primary breast cancer in the elderly patient
    • Foudraine NA, Verhoef LCG, Burghouts JT. Tamoxifen as sole therapy for primary breast cancer in the elderly patient. Lancet 1992; 2:840-842.
    • (1992) Lancet , vol.2 , pp. 840-842
    • Foudraine, N.A.1    Verhoef, L.C.G.2    Burghouts, J.T.3
  • 19
    • 0026727264 scopus 로고
    • Indications for primary tamoxifen therapy in elderly women with breast cancer
    • Gaskell DJ, Hawkins RA, de Carteret S, et al. Indications for primary tamoxifen therapy in elderly women with breast cancer. Br J Surg 1992; 79:1317-1320.
    • (1992) Br J Surg , vol.79 , pp. 1317-1320
    • Gaskell, D.J.1    Hawkins, R.A.2    de Carteret, S.3
  • 20
    • 0028910481 scopus 로고
    • Should tamoxifen be a primary treatment choice for elderly breast cancer patients with locoregional disease?
    • Bergman L, van Dongen JA, van Ooien B, et al. Should tamoxifen be a primary treatment choice for elderly breast cancer patients with locoregional disease? Breast Cancer Res Treat 1995; 34:77-83.
    • (1995) Breast Cancer Res Treat , vol.34 , pp. 77-83
    • Bergman, L.1    van Dongen, J.A.2    van Ooien, B.3
  • 21
    • 0029926851 scopus 로고    scopus 로고
    • Tamoxifen as primary treatment of breast cancer in elderly patients
    • Ciatto S, Cirillo A, Confortini M, et al. Tamoxifen as primary treatment of breast cancer in elderly patients. Neoplasma 1996; 43:43-45.
    • (1996) Neoplasma , vol.43 , pp. 43-45
    • Ciatto, S.1    Cirillo, A.2    Confortini, M.3
  • 22
    • 0033008206 scopus 로고    scopus 로고
    • Lessons from the use of aromatase inhibitors in the neoadjuvant setting
    • Dixon JM, Love CDB, Renshaw L, et al. Lessons from the use of aromatase inhibitors in the neoadjuvant setting. Endocr Relat Cancer 1999; 6:227-230.
    • (1999) Endocr Relat Cancer , vol.6 , pp. 227-230
    • Dixon, J.M.1    Love, C.D.B.2    Renshaw, L.3
  • 23
    • 0036236184 scopus 로고    scopus 로고
    • Endocrine and clinical end points of exemestane as neoadjuvant therapy
    • Miller WR, Dixon JM. Endocrine and clinical end points of exemestane as neoadjuvant therapy. Cancer Control 2002; 9(suppl 2):9-15.
    • (2002) Cancer Control , vol.9 , Issue.SUPPL. 2 , pp. 9-15
    • Miller, W.R.1    Dixon, J.M.2
  • 24
    • 0034131068 scopus 로고    scopus 로고
    • The effects of neoadjuvant anastrozole (Arimidex) on tumor volume in postmenopausal women with breast cancer: A randomized, double-blind, single-center study
    • Dixon JM, Renshaw L, Bellamy C, et al. The effects of neoadjuvant anastrozole (Arimidex) on tumor volume in postmenopausal women with breast cancer: a randomized, double-blind, single-center study. Clin Cancer Res 2000; 6:2229-2235.
    • (2000) Clin Cancer Res , vol.6 , pp. 2229-2235
    • Dixon, J.M.1    Renshaw, L.2    Bellamy, C.3
  • 25
    • 4143101612 scopus 로고    scopus 로고
    • Phase II study of neoadjuvant exemestane in postmenopausal patients with operable breast cancer
    • (Abstract #443)
    • Tubiana-Hulin M, Spyratos F, Becette V, et al. Phase II study of neoadjuvant exemestane in postmenopausal patients with operable breast cancer. Breast Cancer Res Treat 2003; 82(suppl 1):s443 (Abstract #443).
    • (2003) Breast Cancer Res Treat , vol.82 , Issue.SUPPL. 1
    • Tubiana-Hulin, M.1    Spyratos, F.2    Becette, V.3
  • 26
    • 2342461803 scopus 로고    scopus 로고
    • Phase II study to define the safety and efficacy of exemestane as preoperative therapy for postmenopausal patients with primary breast cancer - Final results of the German Neoadjuvant Aromasin Initiative (GENARI)
    • (Abstract #239)
    • Krainick U, Astner A, Jonat W, et al. Phase II study to define the safety and efficacy of exemestane as preoperative therapy for postmenopausal patients with primary breast cancer - final results of the German Neoadjuvant Aromasin Initiative (GENARI). Breast Cancer Res Treat 2003; 82(suppl 1):s55 (Abstract #239).
    • (2003) Breast Cancer Res Treat , vol.82 , Issue.SUPPL. 1
    • Krainick, U.1    Astner, A.2    Jonat, W.3
  • 27
    • 13844279169 scopus 로고    scopus 로고
    • Neoadjuvant letrozole: The Edinburgh experience
    • (Abstract #264)
    • Dixon JM, Jackson J, Renshaw L, et al. Neoadjuvant letrozole: the Edinburgh experience. Breast Cancer Res Treat 2002; 76(suppl 1):s75 (Abstract #264).
    • (2002) Breast Cancer Res Treat , vol.76 , Issue.SUPPL. 1
    • Dixon, J.M.1    Jackson, J.2    Renshaw, L.3
  • 28
    • 33750853420 scopus 로고    scopus 로고
    • Exemestane as neoadjuvant treatment in patients > 65 years with T > 3 cm; preliminary results of a multicenter Spanish phase II trial
    • (Abstract #272)
    • Gil M, Barnadas A, Cirera L, et al. Exemestane as neoadjuvant treatment in patients > 65 years with T > 3 cm; preliminary results of a multicenter Spanish phase II trial. Breast Cancer Res Treat 2002; 76(suppl 1):s77 (Abstract #272).
    • (2002) Breast Cancer Res Treat , vol.76 , Issue.SUPPL. 1
    • Gil, M.1    Barnadas, A.2    Cirera, L.3
  • 29
    • 0003196907 scopus 로고    scopus 로고
    • Anastrozole as neoadjuvant therapy for hormone-dependent locally advanced breast cancer in postmenopausal patients
    • (Abstract #156)
    • Milla-Santos A, Milla L, Rallo L, et al. Anastrozole as neoadjuvant therapy for hormone-dependent locally advanced breast cancer in postmenopausal patients. Proc Am Soc Clin Oncol 2002; 21(suppl 1):40a (Abstract #156).
    • (2002) Proc Am Soc Clin Oncol , vol.21 , Issue.SUPPL. 1
    • Milla-Santos, A.1    Milla, L.2    Rallo, L.3
  • 30
    • 13844290153 scopus 로고    scopus 로고
    • Our first experience with neoadjuvant treatment of postmenopausal locally advanced breast cancer patients with letrozole
    • (Abstract #319)
    • Wagnerova M, Andrasina I, Sokol L, et al. Our first experience with neoadjuvant treatment of postmenopausal locally advanced breast cancer patients with letrozole. Proc Am Soc Clin Oncol 2003; 22:80 (Abstract #319).
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 80
    • Wagnerova, M.1    Andrasina, I.2    Sokol, L.3
  • 31
    • 4143063256 scopus 로고    scopus 로고
    • Anastrozole is an effective neoadjuvant therapy for patients with hormone-dependent locally advanced breast cancer irrespective of cerbB2
    • (Abstract #154)
    • Milla-Santos A, Milla L, Calvo N, et al. Anastrozole is an effective neoadjuvant therapy for patients with hormone-dependent locally advanced breast cancer irrespective of cerbB2. Proc Am Soc Clin Oncol 2003; 22:39 (Abstract #154).
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 39
    • Milla-Santos, A.1    Milla, L.2    Calvo, N.3
  • 32
    • 13844283270 scopus 로고    scopus 로고
    • Open-study evaluation of neoadjuvant hormonal therapy in premenopausal patients with advanced breast cancer
    • (Abstract #2034)
    • Sanchez R, Duarte C, Perry F, et al. Open-study evaluation of neoadjuvant hormonal therapy in premenopausal patients with advanced breast cancer. Proc Am Soc Clin Oncol 2002; 21:56b (Abstract #2034).
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Sanchez, R.1    Duarte, C.2    Perry, F.3
  • 33
    • 3142737587 scopus 로고    scopus 로고
    • Primary hormonal therapy with exemestane in patients with breast tumors > 3 cm in diameter: Results of a Spanish multicenter phase II trial
    • (Abstract #603)
    • Gil MJ, Barnadas A, Cirera L, et al. Primary hormonal therapy with exemestane in patients with breast tumors > 3 cm in diameter: results of a Spanish multicenter phase II trial. Proc Am Soc Clin Oncol 2004; 22:27 (Abstract #603).
    • (2004) Proc Am Soc Clin Oncol , vol.22 , pp. 27
    • Gil, M.J.1    Barnadas, A.2    Cirera, L.3
  • 34
    • 0035692576 scopus 로고    scopus 로고
    • Preoperative treatment of postmenopausal breast cancer patients with letrozole: A randomized double-blind multicenter study
    • Eiermann W, Paepke S, Appfelstaedt J, et al. Preoperative treatment of postmenopausal breast cancer patients with letrozole: a randomized double-blind multicenter study. Ann Oncol 2001; 12:1527-1532.
    • (2001) Ann Oncol , vol.12 , pp. 1527-1532
    • Eiermann, W.1    Paepke, S.2    Appfelstaedt, J.3
  • 35
    • 24644490871 scopus 로고    scopus 로고
    • Neoadjuvant treatment of postmenopausal breast cancer with anastrozole, tamoxifen, or both in combination: The Immediate Preoperative Anastrozole, Tamoxifen, or Combined with Tamoxifen (IMPACT) multicenter double-blind randomized trial
    • Smith IE, Dowsett M, Ebbs SR, et al. Neoadjuvant treatment of postmenopausal breast cancer with anastrozole, tamoxifen, or both in combination: the Immediate Preoperative Anastrozole, Tamoxifen, or Combined with Tamoxifen (IMPACT) multicenter double-blind randomized trial. J Clin Oncol 2005; 23:5108-5116.
    • (2005) J Clin Oncol , vol.23 , pp. 5108-5116
    • Smith, I.E.1    Dowsett, M.2    Ebbs, S.R.3
  • 36
    • 24644468668 scopus 로고    scopus 로고
    • Neoadjuvant endocrine therapy for breast cancer: More questions than answers
    • Ellis MJ. Neoadjuvant endocrine therapy for breast cancer: more questions than answers. J Clin Oncol 2005; 23:4842-4844.
    • (2005) J Clin Oncol , vol.23 , pp. 4842-4844
    • Ellis, M.J.1
  • 37
    • 33646371731 scopus 로고    scopus 로고
    • Comparison of anastrozole versus tamoxifen as preoperative therapy in postmenopausal women with hormone receptor positive breast cancer (PROACT)
    • Cataliotti L, Buzdar A, Noguchi S, et al. Comparison of anastrozole versus tamoxifen as preoperative therapy in postmenopausal women with hormone receptor positive breast cancer (PROACT). Cancer 2006; 106:2095-2103.
    • (2006) Cancer , vol.106 , pp. 2095-2103
    • Cataliotti, L.1    Buzdar, A.2    Noguchi, S.3
  • 38
    • 4944223750 scopus 로고    scopus 로고
    • Anastrozole vs tamoxifen vs combination as neoadjuvant endocrine therapy of postmenopausal breast cancer patients
    • (Abstract #3538)
    • Semiglazov V, Semiglazov VV, Ivanov VG, et al. Anastrozole vs tamoxifen vs combination as neoadjuvant endocrine therapy of postmenopausal breast cancer patients. Proc Am Soc Clin Oncol 2003; 22:880 (Abstract #3538).
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 880
    • Semiglazov, V.1    Semiglazov, V.V.2    Ivanov, V.G.3
  • 39
    • 2342465632 scopus 로고    scopus 로고
    • Neoadjuvant endocrine therapy: Exemestane vs tamoxifen in postmenopausal ER + breast cancer patients (T1-4 N1-2 MO)
    • (Abstract #111)
    • Semiglazov V, Semiglazov VV, Ivanov VG, et al. Neoadjuvant endocrine therapy: exemestane vs tamoxifen in postmenopausal ER + breast cancer patients (T1-4 N1-2 MO). Breast Cancer Res Treat 2003; 82(suppl 1):s22 (Abstract #111).
    • (2003) Breast Cancer Res Treat , vol.82 , Issue.SUPPL. 1
    • Semiglazov, V.1    Semiglazov, V.V.2    Ivanov, V.G.3
  • 40
    • 27744587240 scopus 로고    scopus 로고
    • Neoadjuvant endocrine therapy vs chemotherapy for postmenopausal ER positive breast cancer patients
    • (Abstract #2090)
    • Semiglazov VF, Ivanov VG, Semiglazov VV, et al. Neoadjuvant endocrine therapy vs chemotherapy for postmenopausal ER positive breast cancer patients. Breast Cancer Res Treat 2004; 88(suppl 1): s106 (Abstract #2090).
    • (2004) Breast Cancer Res Treat , vol.88 , Issue.SUPPL. 1
    • Semiglazov, V.F.1    Ivanov, V.G.2    Semiglazov, V.V.3
  • 41
    • 19944408390 scopus 로고    scopus 로고
    • Preoperative gefitinib versus gefitinib and anastrozole in postmenopausal patients with oestrogen-receptor positive and epidermal-growth-factor-receptor-positive primary breast cancer: A double-blind placebo-controlled phase II randomized trial
    • Polychronis A, Sinnett HD, Hadjiminas D, et al. Preoperative gefitinib versus gefitinib and anastrozole in postmenopausal patients with oestrogen-receptor positive and epidermal-growth-factor-receptor-positive primary breast cancer: a double-blind placebo-controlled phase II randomized trial. Lancet Oncol 2005; 6:383-391.
    • (2005) Lancet Oncol , vol.6 , pp. 383-391
    • Polychronis, A.1    Sinnett, H.D.2    Hadjiminas, D.3
  • 42
    • 33749642964 scopus 로고    scopus 로고
    • Biological and clinical outcomes from a phase II placebo-controlled neoadjuvant study of anastrozole alone or with gefitinib in postmenopausal women with ER/PgR+ breast cancer (Study 223)
    • (Abstract #515)
    • Dowsett M, Smith I, Skene A, et al. Biological and clinical outcomes from a phase II placebo-controlled neoadjuvant study of anastrozole alone or with gefitinib in postmenopausal women with ER/PgR+ breast cancer (Study 223). Proc Am Soc Clin Oncol 2006; 24:6s (Abstract #515).
    • (2006) Proc Am Soc Clin Oncol , vol.24
    • Dowsett, M.1    Smith, I.2    Skene, A.3
  • 43
    • 27644447574 scopus 로고    scopus 로고
    • The mammalian target of rapamycin (mTOR) kinase pahway: Its role in tumourigenesis and targeted antitumour therapy
    • Janus A, Robak T, Smolewski P. The mammalian target of rapamycin (mTOR) kinase pahway: its role in tumourigenesis and targeted antitumour therapy. Cell Mol Biol Lett 2005; 10:479-498.
    • (2005) Cell Mol Biol Lett , vol.10 , pp. 479-498
    • Janus, A.1    Robak, T.2    Smolewski, P.3
  • 44
    • 22344446415 scopus 로고    scopus 로고
    • Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer
    • Boulay A, Rudloff J, Ye J, et al. Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer. Clin Cancer Res 2005; 11:5319-5328.
    • (2005) Clin Cancer Res , vol.11 , pp. 5319-5328
    • Boulay, A.1    Rudloff, J.2    Ye, J.3
  • 45
    • 0031915998 scopus 로고    scopus 로고
    • Prognostic and predictive factors in breast cancer by immunohistochemical analysis
    • Allred DC, Harvey JM, Berardo M, et al. Prognostic and predictive factors in breast cancer by immunohistochemical analysis. Mod Pathol 1998; 11:155-168.
    • (1998) Mod Pathol , vol.11 , pp. 155-168
    • Allred, D.C.1    Harvey, J.M.2    Berardo, M.3
  • 46
    • 0035884620 scopus 로고    scopus 로고
    • Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1 and/or ErbB-2 positive, estrogen receptor positive primary breast cancer: Evidence from a phase III randomized trial
    • Ellis MJ, Coop A, Singh B, et al. Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1 and/or ErbB-2 positive, estrogen receptor positive primary breast cancer: evidence from a phase III randomized trial. J Clin Oncol 2001; 19:3808-3816.
    • (2001) J Clin Oncol , vol.19 , pp. 3808-3816
    • Ellis, M.J.1    Coop, A.2    Singh, B.3
  • 47
    • 26044478813 scopus 로고    scopus 로고
    • Can molecular markers predict when to implement treatment with aromatase inhibitors in invasive breast cancer?
    • Tovey S, Dunne B, Witton CJ, et al. Can molecular markers predict when to implement treatment with aromatase inhibitors in invasive breast cancer? Clin Cancer Res 2005; 11:4835-4842.
    • (2005) Clin Cancer Res , vol.11 , pp. 4835-4842
    • Tovey, S.1    Dunne, B.2    Witton, C.J.3
  • 48
    • 20244374413 scopus 로고    scopus 로고
    • Biomarker changes during neoadjuvant anastrozole, tamoxifen, or the combination: Influence of hormonal status and HER-2 in breast cancer - A study from the IMPACT trialists
    • Dowsett M, Ebbs SR, Dixon M, et al. Biomarker changes during neoadjuvant anastrozole, tamoxifen, or the combination: influence of hormonal status and HER-2 in breast cancer - a study from the IMPACT trialists. J Clin Oncol 2005; 23:2477-2492.
    • (2005) J Clin Oncol , vol.23 , pp. 2477-2492
    • Dowsett, M.1    Ebbs, S.R.2    Dixon, M.3
  • 49
    • 10744233578 scopus 로고    scopus 로고
    • Letrozole inhibits tumor proliferation more effectively than tamoxifen independent of HER1/2 expression status
    • Ellis MJ, Coop A, Singh B, et al. Letrozole inhibits tumor proliferation more effectively than tamoxifen independent of HER1/2 expression status. Cancer Res 2003; 63:6523-6531.
    • (2003) Cancer Res , vol.63 , pp. 6523-6531
    • Ellis, M.J.1    Coop, A.2    Singh, B.3
  • 50
    • 0035576786 scopus 로고    scopus 로고
    • HER-2 amplification impedes antiproliferative effects of hormone therapy in estrogen receptor-positive primary breast cancer
    • Dowsett M, Harper-Wynne C, Boeddinghaus I, et al. HER-2 amplification impedes antiproliferative effects of hormone therapy in estrogen receptor-positive primary breast cancer. Cancer Res 2001; 61:8452-8458.
    • (2001) Cancer Res , vol.61 , pp. 8452-8458
    • Dowsett, M.1    Harper-Wynne, C.2    Boeddinghaus, I.3
  • 51
    • 0343584508 scopus 로고    scopus 로고
    • Superior efficacy of letrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer: Results of a phase III study of the International Letrozole Breast Cancer Group
    • Mouridson H, Gershavovitch M, Sun Y, et al. Superior efficacy of letrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer: results of a phase III study of the International Letrozole Breast Cancer Group. J Clin Oncol 2001; 19:2596-2606.
    • (2001) J Clin Oncol , vol.19 , pp. 2596-2606
    • Mouridson, H.1    Gershavovitch, M.2    Sun, Y.3
  • 52
    • 0034669484 scopus 로고    scopus 로고
    • Anastrozole is superior to tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: Results of a North American multicenter randomized trial
    • Arimidex Study Group
    • Nabholtz JM, Buzdar A, Pollak W, et al. Anastrozole is superior to tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: results of a North American multicenter randomized trial. Arimidex Study Group. J Clin Oncol 2000; 18:3758-3767.
    • (2000) J Clin Oncol , vol.18 , pp. 3758-3767
    • Nabholtz, J.M.1    Buzdar, A.2    Pollak, W.3
  • 53
    • 0034669435 scopus 로고    scopus 로고
    • Anastrozole versus tamoxifen as first-line therapy for advanced breast cancer in 668 postmenopausal women: Results of the Tamoxifen and Arimidex Randomized Group Efficacy and Tolerability Study
    • Bonneterre J, Thurlimann B, Robertson JF, et al. Anastrozole versus tamoxifen as first-line therapy for advanced breast cancer in 668 postmenopausal women: results of the Tamoxifen and Arimidex Randomized Group Efficacy and Tolerability Study. J Clin Oncol 2000; 18:3748-3757.
    • (2000) J Clin Oncol , vol.18 , pp. 3748-3757
    • Bonneterre, J.1    Thurlimann, B.2    Robertson, J.F.3
  • 54
    • 11444251764 scopus 로고    scopus 로고
    • Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer
    • Howell A, Cuzik J, Baum M, et al. Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer. Lancet 2005; 365:60-62.
    • (2005) Lancet , vol.365 , pp. 60-62
    • Howell, A.1    Cuzik, J.2    Baum, M.3
  • 55
    • 1642483529 scopus 로고    scopus 로고
    • Prediction of hormone sensitivity by DNA microarray
    • Hayashi S. Prediction of hormone sensitivity by DNA microarray. Biomed Pharmacother 2004; 58:1-9.
    • (2004) Biomed Pharmacother , vol.58 , pp. 1-9
    • Hayashi, S.1


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