Different responses of epicardium and endocardium to K(ATP) channel modulators during regional ischemia

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 271, Issue 1 40-1, 1996, Pages

  Miyoshi, Shunichiro ^a   Miyazaki, Toshihisa ^a   Moritani, Kazunori ^a   Ogawa, Satoshi ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

5 hydroxydecanoate; coronary occlusion; nicorandil

Indexed keywords

POTASSIUM CHANNEL; POTASSIUM ION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DOG; ENDOCARDIUM; EPICARDIUM; HEART INFARCTION; HEART MUSCLE BLOOD FLOW; HEART MUSCLE ISCHEMIA; HEART MUSCLE POTENTIAL; LEFT ANTERIOR DESCENDING CORONARY ARTERY; NONHUMAN; PRIORITY JOURNAL;

EID: 33750829749     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1996.271.1.h140     Document Type: Article

References (30)

1. Bekheit, S. S., M. Restivo, M. Boutjdir, P. Henkin, K. Gooyandeh, M. Assadi, S. Khatib, W. B. Gough, and N. El-Sherif. Effects of glyburide on ischemia-induced changes in extracellular potassium and local myocardial activation: a potential new approach to the management of ischemia-induced malignant ventricular arrhythmias. Am. Heart J. 119: 1025-1033, 1990.
2. Boineau, J. P., and J. L. Cox. Slow ventricular activation in acute myocardial infarction: a source of re-entrant premature ventricular contractions. Circulation 48: 702-713, 1973.
3. Chi, L. G., A. C. Uprichard, and B. R. Lucchesi. Profibrillatory actions of pinacidil in a conscious canine model of sudden coronary death. J. Cardiovasc. Pharmacol. 15: 452-464, 1990.
4. + channels protect the myocardium against ischemia/reperfusion damage. Circ. Res. 69: 571-581, 1991.
5. DiDiego, J. M., and C. Antzelevitch. Pinacidil-induced electrical heterogeneity and extrasystolic activity in canine ventricular tissue. Does activation of ATP-regulated potassium current promote phase 2 reentry? Circulation 88: 1177-1189, 1993.
6. Fujiwara, H., M. Ashraf, S. Sato, and R. W. Millard. Transmural cellular damage and blood flow distribution in early ischemia in pig hearts. Circ. Res. 51: 683-93, 1982.
7. Furukawa, T., S. Kimura, N. Furukawa, A. L. Bassett, and R. J. Myerburg. Role of cardiac ATP-regulated potassium channels in differential responses of endocardial and epicardial cells to ischemia. Circ. Res. 68: 1693-1702, 1991.
8. +. Am. J. Physiol. 235 (Heart Circ. Physiol. 4): H455-H459, 1978.
9. + current by nicorandil (2-nicotinamidoethyl nitrate) in isolated ventricular myocytes. J. Pharmacol. Exp. Ther. 250: 278-285, 1989.
10. + loss and arrhythmias in rat hearts. Effect of glibenclamide, a sulfonylurea. Circ. Res. 66: 478-485, 1990.
11. Kimura, S., A. L. Bassett, T. Kohya, P. Kozlovskis, and R. J. Myerburg. Simultaneous recording of action potentials from endocardium and epicardium during ischemia in isolated cat ventricle: relation of temporal electrophysiologic heterogeneities to arrhythmias. Circulation 86: 401-409, 1986.
12. + channel on ECG ST segment elevation during a bout of myocardial ischemia; a study on epicardial mapping in dogs. Circulation 88: 1845-1851, 1993.
13. Liu, D. W., G. A. Gintant, and C. Antzelevitch. Ionic bases for electrophysiological distinctions among epicardial, midmyocardial, and endocardial myocytes from the free wall of the canine left ventricle. Circ. Res. 72: 671-687, 1993.
14. Lowe, J. E., R. G. Cummings, D. H. Adams, and R. E. Hull. Evidence that ischemic cell death begins in the subendocardium independent of variations in collateral flow or wall tension. Circulation 68: 190-202, 1983.
15. Lukas, A., and C. Antzelevitch. Difference in the electrophysiological response of canine ventricular epicardium and endocardium to ischemia. Role of the transient outward current. Circulation 88: 2903-2915, 1993
16. Miyazaki, T., M. Asanagi, K. Moritani, S. Miyosbi, L. Zhao, H. Mitamura, and S. Ogawa. Comparative effects of adenosine triphosphate-sensitive potassium channel opener and blocker on ischaemia-induced action potential shortening, conduction delay, and ventricular fibrillation in dogs (Abstract). Eur. Heart J. 19: 136, 1994.
17. Miyazaki, T., and D. P. Zipes. Protection against autonomic denervation following acute myocardial infarction by preconditioning ischemia. Circ. Res. 64: 437-448, 1989.
18. Miyazaki, T., and D. P. Zipes. Pericardial prostaglandin biosynthesis prevents the increased incidence of reperfusion-induced ventricular fibrillation produced by efferent sympathetic stimulation in dogs. Circulation 82: 1008-1019, 1990.
19. Miyoshi, S., T. Miyazaki, K. Moritani, M. Asanagi, L. Zhao, K. Sakurai, H. Mitamura, and S. Ogawa. Potassium accumulation in the regionally ischemic myocardium. Different responses in the subepicardial and subendocardial layers to ATP-sensitive potassium channel modulators (Abstract). Circulation 90, Suppl. 1: 1-40, 1994.
20. Moritani, K., T. Miyazaki, S. Miyoshi, M. Asanagi, L. Zhao, H. Mitamura, and S. Ogawa. Blockade of ATP-sensitive potassium channels by 5-hydroxydecanoate suppresses monophasic action potential shortening during regional myocardial ischemia. Cardiovasc. Drugs Ther. 8: 749-756, 1994.
21. McCullough, J. R., D. E. Normandin, M. L. Conder, P. G. Sleph, K. Dzwonezy, and G. J. Grover. Specific block of the antiischemic actions of cromakalim by sodium 5-hydroxydecanoate. Circ. Res. 69: 949-958, 1991.
22. Niho, T., T. Notsu, H. Ishikawa, H. Funato, M. Yamazaki, H. Takahashi, I. Tanaka, M. Kayamoto, T. Dabasaki, F. Yamasaki, T. Shikawa, A. Uemura, and M. Mizota. Study of mechanisms and effects of sodium 5-hydroxydecanoate on experimental ischemic ventricular arrhythmia. Folia Pharmacol. Jpn. 105-167, 1987.
23. + channels in cardiac muscle. Nature Lond. 305: 147-148, 1983.
24. + channels by sodium 5-hydroxydecanoate, a new antiarrhythmic agent in isolated guinea pig heart cells ( Abstract). J. Mol. Cell. Cardiol. 21, Suppl. II: II-9, 1989.
25. + channel by 5-hydroxydecanoate in guinea pig ventricular myocytes. J. Pharmacol Exp. Ther 260: 702-708, 1991.
26. Russel, D. C., H. J. Smith, and M. F. Oliver. Transmembrane potential changes and ventricular fibrillation during repetitive myocardial ischaemia in the dog. Br. Heart J. 42: 88-96, 1979.
27. Taggart, P., P. M. Sutton, D. W. Spear, H. F. Drake, R. H. Swanton, and R. W. Emanuel. Simultaneous endocardial and epicardial monophasic action potential recordings during brief periods of coronary artery ligation in the dog: influence of adrenaline, beta blockade and alpha blockade. Cardiovasc. Res. 22: 900-909, 1988.
28. Wilde, A. A. M., D. Escande, C. A. Schumacher, D. Thuriger, M. Mestre, J. W. T. Fiolet, and M. J. Janse. Potassium accumulation in the globally ischemic mammalian heart: A role for the ATP-sensitive potassium channel. Circ. Res. 67: 835-843, 1990.
29. Wolleben, C. D., M. C. Sanguinetti, and P. K. S. Siegl. Influence of ATP-sensitive potassium channel modulators on ischaemia-induced fibrillation in isolated rat hearts. J. Mol. Cell. Cardiol. 21: 783-788, 1989.
30. ATP channels: an endogenous protective mechanism during repetitive ischemia. Am. J. Physiol. 264 (Heart Circ. Physiol. 33): H495-H504, 1993.