Enhanced growth of hepatic hemangiomatosis in two adults after postmenopausal estrogen replacement therapy

Tohoku Journal of Experimental Medicine

Volumn 210, Issue 3, 2006, Pages 257-261

  Ozakyol, Aysegul ^a,b   Kebapci, Mahmut ^a  

^a ESKISEHIR OSMANGAZI UNIVERSITY   (Turkey)

^b Hasan Polatkan Bulvari   (Turkey)

Author keywords

Estrogen; Hepatic hemangioma; Hepatic hemangiomatosis; Hormone replacement therapy

Indexed keywords

CONJUGATED ESTROGEN; CONJUGATED ESTROGEN PLUS MEDROXYPROGESTERONE ACETATE; LIVER ENZYME; TUMOR MARKER;

ABDOMINAL PAIN; ADULT; ARTICLE; BLOOD ANALYSIS; CASE REPORT; DISEASE ASSOCIATION; DRUG WITHDRAWAL; ECHOGRAPHY; ESTROGEN THERAPY; FEMALE; FOLLOW UP; HEALTH STATUS; HEMANGIOMATOSIS; HORMONE SUBSTITUTION; HOSPITAL ADMISSION; HUMAN; LABORATORY TEST; LIVER HEMANGIOMA; LIVER NODULE; LIVER SCINTISCANNING; MEDICAL DECISION MAKING; MENOPAUSAL SYNDROME; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSICAL EXAMINATION; POSTMENOPAUSE; TREATMENT PLANNING; TUMOR GROWTH; TUMOR VOLUME; TURKEY (REPUBLIC);

EID: 33750826579     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.210.257     Document Type: Article

References (24)

1. Balaci, E., Sumner, T.E., Auringer, S.T. & Cox, T.D. (1999) Diffuse neonatal hemangiomatosis with extensive involvement of the brain and cervical spinal cord. Pediatr. Radiol., 29, 441-443.
2. Christopherson, W.M., Mayo, E.T. & Barrows, G.H. (1975) Liver tumors in women on contraceptive steroids. Obstet. Gynecol., 46, 221-223.
3. Conter, R.L & Longmire, W.P. (1988) Recurrent hepatic hemangiomas: Possible association with estrogen therapy. Ann. Surg., 20, 115-119.
4. El-Hashemite, N., Walker, V. & Kwiatkowski, D.J. (2005) Estrogen enhances whereas tamoxifen retards development of Tsc mouse liver hemangioma: A tumor related to renal angiomyolipoma and pulmonary lymphangioleiomyomatosis. Cancer Res., 65, 2474-2481.
5. Falappa, P., Preziosi, P., Cotroneo, A.R. & Danza, F.M. (1983) Hepatic hemangiomas on 33 patients. Evaluation by ultrasound, nuclear medicine, computed tomography and angiography. Diagn. Imaging., 52, 245-254.
6. Feurle, G.E. (1990) Arteriovenous shunting and cholestasis in hepatic hemangiomatosis associated with metoclopramide. Gastroenterology, 99, 258-262.
7. Gemer, O., Moscovici, O., Dosoretz ben-Horin, C.L., Linov, L., Peled, R. & Segal, S. (2004) Oral contraceptives and liver hemangioma: a case-control study. Acta Obstet. Gynecol. Scand., 83, 1199-1202.
8. Glinkova, V., Shevah, O., Boaz, M., Levine, A. & Shirin, H. (2004) Hepatic haemangiomas: Possible association with female sex hormones. Gut, 53, 1352-1356.
9. Herman, P., Costa, M.L., Machado, M.A., Pugliese, V., D'Albuquerque, L.A., Machado, M.C., Gama-Rodrigues, J.J. & Saad, W.A. (2005) Management of hepatic hemangiomas: A 14 year experience. J. Gastrointest. Surg., 9, 853-859.
10. Jayanti, V., Shankar, T.R., Ravidran, C., Sudalaimuthu, S. & Chandrasekar, T.S. (2000) Diffuse hepatic hemangiomatosis: Case report. Trop. Gastroenterol., 21, 188-189.
11. Langner, C., Thonhofer, R., Hegenbarth, K. & Trauner, M. (2001) Diffuse hemangiomatosis of the liver and spleen in an adult. Pathologe, 22, 424-428.
12. Lehmann, F.S., Beglinger, C., Schabel, K. & Terracciano, L. (1999) Progressive development of diffuse liver hemangiomatosis. J. Hepatol., 30, 951-954.
13. Lui, W., Zhang, S., Hu, T., Wei, F., Guo, Y. & Cheng, N. (1997) Sex hormone receptors of hemangiomas in children. Chin. Med. J., 110, 349-351.
14. McFarland, E.G., Mayo-Smith, W.W., Saini, S., Hahn, P.F., Goldberg, M.A. & Lee, M.J. (1994) Hepatic hemangiomas and malignant tumors: improved differentiation with heavily T2 weighted conventional spin-echo MR imaging. Radiology, 193, 43-47.
15. Mesurolle, B., Wexler, M., Halwani, F., Aldis, A., Veksler, A. & Kao, E. (2003) Caverneous hemangioma of the breast: mammographic and sonographic findings and follow-up in a patient receiving hormone-replacement therapy. J. Clin. Ultrasound., 31, 430-436.
16. Moon, W.S., Yu, H.C., Lee, J.M. & Kang, M.J. (2000) Diffuse hepatic hemangiomatosis in an adult. J. Korean Med. Sci., 15, 471-474.
17. Ochsner, K.L. & Halpert, B. (1958) Cavernous hemangioma of the liver. Surgery, 43, 577-582.
18. Porayko, M.K. & Choudhray, C. (2001) Benign neoplasms of the liver. Curr. Treat. Options Gastroenterol., 4, 479-491.
19. Reddy, K.R., Kligerman, S., Levi, J., Livingstone, A., Molina, E., Franceschi, D., Badalement, S., Jeffres, L., Tzakis, A. & Schiff, E.R. (2001) Benign and solid tumors of the liver: relationship to sex, age, size of tumors, and outcome. Am. Surg., 67, 173-178.
20. Saegusa, T., Ito, K., Oba, N., Matsuda, M., Kojima, K., Tohyama, K., Matsumoto, M., Miura, K. & Suzuki, M. (1995) Enlargement of multiple cavernous hemangioma of the liver in association with pregnancy. Intern. Med., 34, 207-211.
21. Schaper, H.W., McGowan, K.A., Kim-Schulze, S. & Cid, M.C. (1996) Estrogen and endothelial cell angiogenic activity. Clin. Exp. Pharmacol. Physiol., 23, 247-250.
22. Startte, E.G., Tope, W.D., Johnson, C.L. & Swanson, N.A. (1996) Multimodal management of diffuse neonatal hemangiomatosis. J. Am. Acad. Dermatol., 34, 337-342.
23. Xiao, X., Hong, L. & Sheng, M. (1999) Promoting effect of estrogen on the proliferation of hemangioma vascular endothelial cells in vitro. J. Pediatr. Sur., 34, 1603-1605.
24. Xiao, X., Liu, J. & Sheng, M. (2004) Synergistic effect of estrogen and VEGF on the proliferation of hemangioma vascular endothelial cells. J. Pediatr. Surg., 39, 1107-1110.