Subthalamic nucleus neurones in slices from 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mice show irregular, dopamine-reversible firing pattern changes, but without synchronous activity

Neuroscience

Volumn 143, Issue 2, 2006, Pages 565-572

  Wilson, C L ^a   Cash, D ^c   Galley, K ^c   Chapman, H ^d   Lacey, M G ^b   Stanford, I M ^a  

^a ASTON UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d GLAXOSMITHKLINE   (United Kingdom)

Author keywords

basal ganglia; dopamine; in vitro; MPTP; Parkinson's disease; single unit

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 2 AMINO 5 PHOSPHONOVALERIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; DOPAMINE; IONOTROPIC RECEPTOR ANTAGONIST; PICROTOXIN; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN INJURY; BRAIN SLICE; CELL ACTIVITY; CELL COUNT; COMPARATIVE STUDY; CONTROLLED STUDY; CORPUS STRIATUM; CORTICAL SYNCHRONIZATION; DISEASE ACTIVITY; DOPAMINE BRAIN LEVEL; GLOBUS PALLIDUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; MEASUREMENT; MOUSE; NERVE CELL; NONHUMAN; OBSERVATION; OSCILLATION; PARKINSON DISEASE; PRIORITY JOURNAL; REDUCTION KINETICS; SUBSTANTIA NIGRA; SUBTHALAMIC NUCLEUS; VARIANCE;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ACTION POTENTIALS; ANIMALS; BRAIN CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; NEURONS; NEUROTOXINS; SUBTHALAMIC NUCLEUS;

EID: 33750813850     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2006.07.051     Document Type: Article

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