Relationship between smoking and folic acid, vitamin B12 and some haematological variables in patients with chronic periodontal disease

Journal of Clinical Periodontology

Volumn 33, Issue 12, 2006, Pages 878-884

  Erdemir, Ebru Olgun ^a   Bergstrom, Jan ^b  

^a KIRIKKALE UNIVERSITY   (Turkey)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Chronic periodontitis; Folic acid; Smoking; Vitamin B12

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; HEMOGLOBIN;

ADULT; AGED; ARTICLE; BLOOD; BLOOD CELL COUNT; CHRONIC DISEASE; CLASSIFICATION; COMPARATIVE STUDY; FEMALE; GINGIVA BLEEDING; GINGIVITIS; HUMAN; LEUKOCYTE COUNT; MALE; MIDDLE AGED; PERIODONTAL DISEASE; PERIODONTICS; PERIODONTITIS; SMOKING; TOOTH PLAQUE;

ADULT; AGED; BLOOD CELL COUNT; CHRONIC DISEASE; DENTAL PLAQUE INDEX; FEMALE; FOLIC ACID; GINGIVAL HEMORRHAGE; GINGIVITIS; HEMOGLOBINS; HUMANS; LEUKOCYTE COUNT; MALE; MIDDLE AGED; PERIODONTAL ATTACHMENT LOSS; PERIODONTAL DISEASES; PERIODONTAL INDEX; PERIODONTAL POCKET; SMOKING; VITAMIN B 12;

EID: 33750810808     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/j.1600-051X.2006.01003.x     Document Type: Article

References (80)

1. Ainamo, J. & Bay, I. (1975) Problems and proposals for recording gingivitis and plaque. International Dental Journal 25, 229-235.
2. Albandar, J. M., Streckfus, C. F., Adesanya, M. R. & Winn, D. (2000) Cigar pipe and cigarette smoking as risk factors for periodontal disease and tooth loss. Journal of Periodontology 71, 1874-1881.
3. Anderson, R., Theron, A. J., Richards, G. A., Myer, M. S. & van Rensburg, A. S. (1991) Passive smoking by humans sensitizes circulating neutrophils. American Review of Respiratory Disease 144, 570-574.
4. Axelsson, P., Paulander, J. & Lindhe, J. (1998) Relationship between smoking and dental status in 35- 50- 65- and 75- year old individuals. Journal of Clinical Periodontology 25, 297-305.
5. Bergstrom, J. (1989) Cigarette smoking as risk factor in chronic periodontal disease. Community Dentistry of Oral Epidemiology 17, 245-247.
6. Bergstrom, J. (1990) Oral hygiene compliance and gingivitis expression in cigarette smokers. Scandinavian Journal of Dental Research 98, 497-503.
7. Bergstrom, J. (1999) Tobacco smoking and supragingival dental calculus. Journal of Clinical Periodontology 26, 541-547.
8. Bergstrom, J. (2003) Tobacco smoking and risk for periodontal disease. Journal of Clinical Periodontology 30, 107-113.
9. Bergstrom, J. & Bostrom, L. (2001) Tobacco smoking and periodontal haemorrhagic responsiveness. Journal of Clinical Periodontology 28, 680-685.
10. Bergstrom, J. & Eliasson, S. (1987a) Cigarette smoking and alveolar bone height in subjects with high standard of oral hygiene. Journal of Clinical Periodontology 14, 466-469.
11. Bergstrom, J. & Eliasson, S. (1987b) Noxious effect of cigarette smoking on periodontal health. Journal of Periodontal Research 22, 513-517.
12. Bergstrom, J., Eliasson, S. & Dock, J. (2000) A 10-year prospective study of tobacco smoking and periodontal health. Journal of Periodontology 71, 1338-1347.
13. Bergstrom, J. & Preber, H. (1986) The influence of cigarette smoking on the development of experimental gingivitis. Journal of Periodontal Research 21, 668-676.
14. Bergstrom, J. & Preber, H. (1994) Tobacco use as a risk factor. Journal of Periodontology 65, 545-550.
15. Borrell, L. N. & Papapanou, P. N. (2005) Analytical epidemiology of periodontitis. Journal of Clinical Periodontology 32 (Suppl. 6), 132-158.
16. Bridges, R. B., Wyatt, R. J. & Rehm, S. R. (1985) Effect of smoking on peripheral blood leukocytes and serum antiproteases. European Journal of Respiratory Disease 66, 24-33.
17. Chen, A. T. L., Reidy, J. A., Annest, I. L., Wetty, T. K. & Zhou, H. G. (1989) Increased chromosome fragility as a consequence of blood folate levels. Smoking and coffee consumption. Environmental and Molecular Mutagenesis 13, 319-324.
18. Consensus Report. (1999) Chronic periodontitis. Annals of Periodontology 4, 38-39.
19. Corre, F., Lellouch, J. & Schwartz, D. (1971) Smoking and leukocyte-counts. Results of an epidemiological survey.. The Lancet 2, 632-634.
20. da Costa, M. & Rothenberg, S. (1974) Appearance of folate binder in leukocytes and serum of women who are pregnant or taking oral contraceptives. Journal of Laboratory and Clinical Medicine 83, 207-214.
21. Dastur, D. K., Quadros, E. V., Wadia, N. H., Deasi, M. M. & Braucha, E. P. (1972) Effect of vegetarianism and smoking on vitamin B12, thiocyanate, and folate levels in the blood of normal subjects. British Medical Journal 3, 260-263.
22. David, S. & Eaton, C. B. (2003) Comment on the public health implications of smoking-induced decreased serum and red blood cell folate levels. Nicotine and Tobacco Research 5, 397-399.
23. Dietrich, T., Bernimoulin, J.-P. & Glynn, R. J. (2004) The effect of cigarette smoking on gingival bleeding. Journal of Periodontology 75, 16-22.
24. Enwonwu, C. O. & Sanders, C. (2001) Nutrition: impact on oral and systemic health. Compendium of Continuing Education in Dentistry 22, 12-18.
25. Feldman, R. S., Bravacos, J. S. & Rose, C. L. (1983) Associations between smoking different tobacco products and periodontal disease indexes. Journal of Periodontology 54, 481-487.
26. Francis, K. T., Thompson, W. & Krumdieck, C. L. (1977) Reaction of tetrahydrofolic acid with cyanate from urea solutions. Formation of an inactive folate derivative. American Journal of Clinical Nutrition 30, 2028-2032.
27. Fredriksson, M., Figuereda, C., Gustafson, A., Bergstrom, K. & Asman, B. (1999) Effect of periodontitis and smoking on blood leukocytes and acute-phase proteins. Journal of Clinical Periodontology 70, 1355-1360.
28. Fredriksson, M., Gustafson, A., Asman, B. & Bergstrom, K. (1998) Hyperreactive peripheral neutrophils in adult periodontitis: generation of chemiluminescence and intracellular hydrogen peroxide after in vitro priming and Fcγ-R stimulation. Journal of Clinical Periodontology 25, 394-398.
29. Genco, R. J. (1996) Current view of risk factors for periodontal disease. Journal of Periodontology 67, 1041-1049.
30. Genco, R. J. & Löe, H. (1993) The role of systemic conditions and disorders in periodontal disease. Periodontology 2000 2, 98-116.
31. Grossi, S. G., Genco, R. J., Machtei, E. E., Ho, A. W., Koch, G., Dunford, R., Zambon, J. J. & Hausmann, E. (1995) Assessment of risk for periodontal disease. II. Risk indicators for alveolar bone loss. Journal of Periodontology 66, 23-29.
32. Grossi, S. G., Zambon, J. J., Ho, A. W., Koch, G., Dunford, R., Machtei, E., Norderyd, O. & Genco, R. J. (1994) Assessment of risk for periodontal disease. I. Risk indicators for attachment loss. Journal of Periodontology 65, 260-267.
33. Haber, J., Wattles, J., Crowley, M. & Mandell, R. (1993) Evidence for cigarette smoking as a major risk factor for periodontitis. Journal of Periodontology 64, 16-23.
34. Haffajee, A. D. & Socransky, S. S. (2001) Relationship of cigarette smoking to attachment level profiles. Journal of Clinical Periodontology 28, 283-295.
35. Haller, J. (1999) The vitamin status and its adequacy in the elderly: in international review. International Journal for Vitamin and Nutrition Research 69, 160-168.
36. Heitz-Mayfield, L. J. A. (2005) Disease progression: identification of high-risk groups and individuals for periodontitis. Journal of Clinical Periodontology 32 (Suppl. 6), 196-209.
37. Herbert, V. (1998) Vitamin B12: plant sources, requirements, and assays. American Journal of Clinical Nutrition 48, 852-858.
38. Khaled, M. A., Watkins, C. L. & Krumdieck, C. L. (1986) Inactivation of B12 and folate coenzymes by butyl nitrite as observed by NMR: implications on one-carbon transfer mechanism. Biochemical and Biophysical Research Communications 135, 201-207.
39. Kinane, D. F. & Chestnutt, I. G. (2000) Smoking and periodontal disease. Critical Reviews in Oral Biology and Medicine 11, 356-365.
40. Krause, M. & Mahan, L. (1984) Food and Nutrition Diet Therapy, 7th Edn, pp. 677-679. Philadelphia: W.B. Saunders.
41. Lee, R. (1993) Nutritional factors in the production and function of erythrocytes. In: Lee, R. G., Bithel, T. C., Foerster, J., Athens, J. W. & Lukens, J. N. eds. Wintrobe's Clinical Hematology, 9th Edn, pp. 158-194. Philadelphia: Lea and Febiger.
42. Lie, M. A., Timmerman, M. F., van der Velden, U. & van der Weijden, G. A. (1998) Evaluation of two methods to assess gingival bleeding in smokers and non-smokers in natural and experimental gingivitis. Journal of Clinical Periodontology 25, 814-821.
43. Linden, G. J. & Mullally, B. H. (1994) Cigarette smoking and periodontal destruction in young adults. Journal of Periodontology 65, 718-723.
44. Linnell, J. C., Smith, A. D. M., Smith, C. L., Wilson, J. & Matthews, D. M. (1986) Effects of smoking on metabolism and excretion of vitamin B12. British Medical Journal 2, 215-216.
45. Löe, H. & Silness, J. (1963) Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontologica Scandinavica 21, 533-551.
46. 12, folate, homocysteine and cognition in the elderly. Scandinavian Journal of Nutrition 47, 132-138.
47. MacFarlane, G. D., Herzberg, M. C., Wolff, L. F. & Hardie, N. A. (1992) Refractory periodontitis associated with abnormal polymorphonuclear leukocyte phagocytosis and cigarette smoking. Journal of Periodontology 63, 908-913.
48. Machuca, G., Rosales, I., Lacalle, J. R., Machuca, C. & Bullon, P. (2000) Effect of cigarette smoking on periodontal status of healthy young adults. Journal of Periodontology 71, 73-78.
49. Mansoor, M., Kristensen, O., Hervig, T., Drablos, P. A., Jacob, A., Stakkestad, J. A., Woie, L., Hetland, Q. & Osland, A. (1997) Low Concentrations of folate in serum and erythrocytes of smokers: methionine loading decreases folate concentrations in serum of smokers and non-smokers. Clinical Chemistry 43, 2192-2194.
50. Nakazawa, Y., Chiba, K., Imatoh, N., Kotorii, T., Sakamato, T. & Ishizaki, T. (1983) Serum folic acid levels and antipyrine clearance rates in smokers and non-smokers. Drug and Alcohol Dependence 11, 201-207.
51. Nishida, N., Tanaka, M., Hayashi, N., Nagata, H., Takeshita, T., Nakayama, K., Morimoto, K. & Shizukuishi, S. (2005) Determination of smoking and obesity as periodontitis risks using the classification and regression tree method. Journal of Periodontology 76, 923-928.
52. Nunn, M. (2003) Understanding the etiology of periodontitis: an overview of periodontal risk factors. Periodontology 2000 32, 11-23.
53. O'Callaghan, P., Meleady, R., Fitzgerald, T. & Graham, I. (2002) Smoking and plasma homocysteine. European Heart Journal 23, 1580-1586.
54. Ozerol, E., Ozerol, I., Gokdeniz, R., Temel, I. & Akyol, O. (2004) Effect of smoking on serum concentrations of total homocysteine, folate, vitamin B12, and nitric oxide in pregnancy: a preliminary study. Fetal Diagnosis and Therapy 19, 145-148.
55. Pabst, M. J., Pabst, K. M., Collier, J. A, Coleman, T. C., Lemons-Prince, M. R., Godat, M. S., Waring, M. B. & Babu, J. P. (1995) Inhibition of neutrophil and monocyte defensive functions by nicotine. Journal of Periodontology 66, 1047-1055.
56. Pack, A. R. (1984) Folate mouthwash: effects on established gingivitis in periodontal patients. Journal of Clinical Periodontology 11, 619-628.
57. Pack, A. R. & Thomson, M. E. (1980) Effects of topical and systemic folic acid supplementation on gingivitis in pregnancy. Journal of Clinical Periodontology 7, 402-414.
58. Palmer, R. M., Wilson, R. F., Hasan, A. S. & Scott, D. (2005) Mechanism of action of environmental factors. Tobacco smoking. Journal of Clinical Periodontology 32 (Suppl. 6), 180-195.
59. Persson, L., Bergstrom, J., Ito, H. & Gustafsson, A. (2001) Tobacco smoking and neutrophil activity in patients with periodontal disease. Journal of Periodontology 72, 90-95.
60. Piyathilake, C. J., Hine, R. J., Dasanayake, A. P., Richards, E. W., Freeberg, L. E., Vaughn, W. H. & Krumdieck, C. L. (1992) Effect on smoking on folate levels in buccal mucosal cells. International Journal of Cancer 52, 566-569.
61. Piyathilake, C. J., Macaluso, M., Hine, R. J., Richards, E. W. & Krumdieck, C. L. (1994) Local and systemic effects of cigarette smoking on folate and vitamin B12. American Journal of Clinical Nutrition 60, 559-566.
62. Preber, H. & Bergstrom, J. (1985) Occurrence of gingival bleeding in smoker and nonsmoker patients. Acta Odontologica Scandinavica 43, 315-320.
63. Preston, A. M. (1991) Cigarette smoking - nutritional implications. Progress in Food and Nutrition Science 15, 183-217.
64. Ryder, M. I., Fujitaki, R., Johnson, G. & Hyun, W. (1998a) Alterations of neutrophil oxidative burst by in vitro smoke exposure: implications for oral and systemic diseases. Annals of Periodontology 3, 76-87.
65. Ryder, M. I., Fujitaki, R., Lebus, S., Mahboub, M., Faia, B., Muhaimin, D., Hamada, M. & Hyun, W. (1998b) Alterations of neutrophil L-selection and CD18 expression by tobacco smoke: implications for periodontal diseases. Journal of Periodontal Research 33, 359-368.
66. Silness, J. & Löe, H. (1964) Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta Odontologica Scandinavica 22, 121-135.
67. Snow, C. F. (1999) Laboratory diagnosis of vitamin B12 and folate deficiency: a guide for the primary care physician. Archives of Internal Medicine 159, 1289-1298.
68. Stallone, D. D. (1994) The influence of obesity and its treatment on the immune system. Nutrition Reviews 52, 37-50.
69. Stedman, R. L. (1968) The chemical composition of tobacco and tobacco smoke. Chemical Reviews 68, 153-207.
70. Stoltenberg, J. L., Osborn, J. B. & Philström, B. L. (1993) Association between cigarette smoking, bacterial pathogens, and periodontal status. Journal of Periodontology 64, 1225-1230.
71. Tanaka, S., Inoue, S., Isoda, F., Wasada, M., Ishihara, M., Yamakawa, T., Sugiyama, A., Takamura, Y. & Okuda, K. (1993) Impaired immunity in obesity: suppressed but reversible lymphocyte responsiveness. International Journal of Obesity and Related Metabolic Disorders 17, 631-636.
72. Thomson, M. E. & Pack, A. R. (1982) Effects of extended systemic and topical folate supplementation on gingivitis of pregnancy. Journal of Clinical Periodontology 9, 275-280.
73. Tonetti, M. S. & Claffey, N. (2005) Advances in the progression of periodontitis and proposal of definitions of a periodontitis case and disease progression for use in risk factor research. Group C Consensus report of the 5th European workshop in periodontology. Journal of Clinical Periodontology 32 (Suppl. 6), 210-213.
74. Vogel, R. I., Fink, R. A., Frank, O. & Baker, H. (1978) The effect of topical application of folic acid on gingival health. Journal of Oral Medicine 33, 22-22.
75. Vogel, R. I., Fink, R. A., Schneider, L. C., Frank, O. & Baker, H. (1976) The effect of folic acid on gingival health. Journal of Periodontology 47, 667-668.
76. Wang, G., Dai, J., Mao, J., Zeng, X., Yang, X. & Wang, X. (2005) Folic acid reverses hyperresponsiveness of LPS-induced chemokine secretion from monocytes in patients with hyperhomocysteinemia. Atherosclerosis 179, 395-402.
77. van der Weijden, G. A., De Slegte, C., Timmerman, M. F. & van der Velden, U. (2001) Periodontitis in smokers and non-smokers: intra-oral distribution of pockets. Journal of Clinical Periodontology 28, 955-960.
78. van Wersch, J. W., Janssens, Y. & Zandvoort, J. A. (2002) Folic acid, Vitamin B(12), and homocysteine in smoking and non-smoking pregnant women. European Journal of Obstetrics and Gynecology and Reproductive Biology 103, 18-21.
79. Witter, F. R., Blake, D. A., Baumgadner, R., Mellits, E. D. & Niebyl, J. R. (1982) Folate, carotene and smoking. American Journal of Obstetrics and Gynecology 144, 857.
80. Zambon, J. J., Grossi, S. G., Machtei, E. E., Ho, A. W., Dunford, R. & Genco, R. J. (1996) Cigarette smoking increases the risk for subgingival infection with periodontal pathogens. Journal of Periodontology 67, 1050-1054.