A further study on the combined use of internal standard and isotope-labeled derivatization reagent for expansion of linear dynamic ranges in liquid chromatography-electrospray mass spectrometry

Biomedical Chromatography

Volumn 20, Issue 10, 2006, Pages 1049-1055

  Tsukamoto, Yuhki ^a   Santa, Tomofumi ^a   Yoshida, Hiroo ^b   Miyano, Hiroshi ^b   Fukushima, Takeshi ^c   Hirayama, Kazou ^b   Imai, Kazuhiro ^d   Funatsu, Takashi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b AJINOMOTO CO INC   (Japan)

^c UNIVERSITY OF SHIZUOKA   (Japan)

^d MUSASHINO UNIVERSITY   (Japan)

Author keywords

Benzofurazan; Fatty acid; Isotope labeled derivatization; LC MS; Metabolite analysis

Indexed keywords

CALIBRATION; FATTY ACIDS; ION SOURCES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

ANALYTES; BENZOFURAZAN; CALIBRATION CURVES; DERIVATIZATION REAGENT; DERIVATIZATIONS; INTERNAL STANDARDS; ISOTOPE-LABELED DERIVATIZATION; LINEAR DYNAMIC RANGES; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; METABOLITE ANALYSIS;

ISOTOPES;

FENOPROFEN; IBUPROFEN; KETOPROFEN; REAGENT;

AQUEOUS SOLUTION; ARTICLE; CALIBRATION; CHEMICAL ANALYSIS; DERIVATIZATION; DRUG DETERMINATION; ELECTROSPRAY MASS SPECTROMETRY; ISOTOPE LABELING; LINEAR SYSTEM; LIQUID CHROMATOGRAPHY; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; STANDARD;

EID: 33750806865     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.636     Document Type: Article

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