Activity and mode of action against fungal phytopathogens of bovine lactoferricin-derived peptides

Journal of Applied Microbiology

Volumn 101, Issue 6, 2006, Pages 1199-1207

  Munoz A ^a   Marcos, J F ^a  

^a INSTITUTO DE AGROQUÍMICA Y TECNOLOGÍA DE ALIMENTOS CSIC   (Spain)

Author keywords

Antimicrobial peptide; Citrus fruits; Lactoferrin; Penicillium digitatum

Indexed keywords

AMINO ACIDS; CITRUS FRUITS; FUNGI; MAMMALS; MICROORGANISMS;

AMINO ACID RESIDUES; ANTIBACTERIALS; ANTIMICROBIAL PEPTIDE; BOVINE LACTOFERRICIN; IN-VITRO; LACTOFERRIN; MODE OF ACTION; PENICILLIUM DIGITATUM; PHYTOPATHOGENS; SYNTHETIC PEPTIDE;

PEPTIDES;

AMINO ACID; CHITIN; LACTOFERRICIN B; LACTOFERRICIN B [17-31]; LACTOFERRICIN B [20-25]; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

AMINO ACID; ANTIMICROBIAL ACTIVITY; CATTLE; FUNGUS; INOCULATION; MICROORGANISM; PATHOGEN; PEPTIDE; PROTEIN; SPORE;

AGRONOMIC TRAIT; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; CARBOHYDRATE ABSORPTION; CONCENTRATION RESPONSE; CONIDIUM; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; FUNGAL CELL; FUNGICIDAL ACTIVITY; FUNGUS GROWTH; FUNGUS HYPHAE; FUNGUS SPORE; GROWTH INHIBITION; IN VITRO STUDY; INOCULATION; MANDARIN; MICROSCOPY; MYCELIUM; MYCOSIS; NONHUMAN; PENICILLIUM DIGITATUM; PERMEABILITY; PLANT DISEASE; PROTECTION; SPOROGENESIS;

BOS TAURUS; CITRUS; FUNGI; PENICILLIUM DIGITATUM;

EID: 33750795816     PISSN: 13645072     EISSN: 13652672     Source Type: Journal    
DOI: 10.1111/j.1365-2672.2006.03089.x     Document Type: Article

References (40)

1. Ali, G.S. and Reddy, A.S. (2000) Inhibition of fungal and bacterial plant pathogens by synthetic peptides: in vitro growth inhibition, interaction between peptides and inhibition of disease progression. Mol Plant-Microbe Interact 13, 847-859.
2. Bellamy, W., Takase, M., Yamauchi, K., Wakabayashi, H., Kawase, K. and Tomita, M. (1992) Identification of the bactericidal domain of lactoferrin. Biochim Biophys Acta 1121, 130-136.
3. Bellamy, W., Wakabayashi, H., Takase, M., Kawase, K., Shimamura, S. and Tomita, M. (1993) Role of cell-binding in the antibacterial mechanism of lactoferricin B. J Appl Bacteriol 75, 478-484.
4. Bellamy, W., Yamauchi, K., Wakabayashi, H., Takase, M., Takakura, N., Shimamura, S. and Tomita, M. (1994) Antifungal properties of Lactoferricin-B, a peptide derived from the N-terminal region of bovine Lactoferrin. Lett Appl Microbiol 18, 230-233.
5. Broekaert, W.F., Terras, F.R.G., Cammue, B.P.A. and Vanderleyden, J. (1990) An automated quantitative assay for fungal growth-inhibition. FEMS Microbiol Lett 69, 55-59.
6. Brogden, K.A. (2005) Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat Rev Microbiol 3, 238-250.
7. Casteels, P., Ampe, C., Jacobs, F., Vaeck, M. and Tempst, P. (1989) Apidaecins - antibacterial peptides from honeybees. EMBO J 8, 2387-2391.
8. Cavallarín, L., Andreu, D. and San Segundo, B. (1998) Cecropin A-derived peptides are potent inhibitors of fungal plant pathogens. Molec Plant-Microbe Interact 11, 218-227.
9. Chong, D.K. and Langridge, W.H. (2000) Expression of full-length bioactive antimicrobial human lactoferrin in potato plants. Transgenic Res 9, 71-78.
10. Coca, M., Bortolotti, C., Rufat, M., Peñas, G., Eritja, R., Tharreau, D., Martínez del Pozo, A., Messeguer, J. et al. (2004) Transgenic rice plants expressing the antifungal AFP protein from Aspergillus giganteus show enhanced resistance to the rice blast fungus Magnaporthe grisea. Plant Mol Biol 54, 245-259.
11. Farnaud, S. and Evans, R.W. (2003) Lactoferrin - a multifunctional protein with antimicrobial properties. Mol Immunol 40, 395-405.
12. Farnaud, S., Spiller, C., Moriarty, L., Patel, A., Gant, V., Odell, E.W. and Evans, R. (2004) Interactions of lactoferricin-derived peptides with LPS and antimicrobial activity. FEMS Microbiol Lett 233, 193-199.
13. Gonzalez, C.F., Provin, E.M., Zhu, L. and Ebbole, D.J. (2002) Independent and synergistic activity of synthetic peptides against thiabendazole-resistant Fusarium sambucinum. Phytopathology 92, 917-924.
14. Hancock, R.E.W. and Chapple, D.S. (1999) Peptide antibiotics. Antimicrob Agents Chemother 43, 1317-1323.
15. Haug, B.E. and Svendsen, J.S. (2001) The role of tryptophan in the antibacterial activity of a 15-residue bovine lactoferricin peptide. J Pept Sci 7, 190-196.
16. van der Kraan, M.I.A., van Marle, J., Nazmi, K., Groenink, J., Van't Hof, W., Veerman, E.C.I., Bolscher, J.G.M. and Arnerongen, A.V.N. (2005) Ultrastructural effects of antimicrobial peptides from bovine lactoferrin on the membranes of Candida albicans and Escherichia coli. Peptides 26, 1537-1542.
17. Lee, T.J., Coyne, D.P., Clemente, T.E. and Mitra, A. (2002) Partial resistance to bacterial wilt in transgenic tomato plants expressing antibacterial lactoferrin gene. J Am Soc Hort Sci 127, 158-164.
18. López-García, B., Pérez-Payá, E. and Marcos, J.F. (2002) Identification of novel hexapeptides bioactive against phytopathogenic fungi through screening of a synthetic peptide combinatorial library. Appl Environ Microbiol 68, 2453-2460.
19. López-García, B., González-Candelas, L., Pérez-Payá, E. and Marcos, J.F. (2000) Identification and characterization of a hexapeptide with activity against phytopathogenic fungi that cause postharvest decay in fruits. Mol Plant-Microbe Interact 13, 837-846.
20. López-García, B., Veyrat, A., Pérez-Payá, E., González-Candelas, L. and Marcos, J.F. (2003) Comparison of the activity of antifungal hexapeptides and the fungicides thiabendazole and imazalil against postharvest fungal pathogens. Int J Food Microbiol 89, 163-170.
21. Moreno, A.B., Martínez del Pozo, A., Borja, M. and San Segundo, B. (2003) Activity of the antifungal protein from Aspergillus giganteus against Botrytis cinerea. Phytopathology 93, 1344-1353.
22. Nandi, S., Suzuki, Y.A., Huang, J.M., Yalda, D., Pham, P., Wu, L.Y., Bartley, G., Huang, N. et al. (2002) Expression of human lactoferrin in transgenic rice grains for the application in infant formula. Plant Sci 163, 713-722.
23. Nikawa, H., Fukushima, H., Makihira, S., Hamada, T. and Samaranayake, L.P. (2004) Fungicidal effect of three new synthetic cationic peptides against Candida albicans. Oral Dis 10, 221-228.
24. Oard, S., Rush, M.C. and Oard, J.H. (2004) Characterization of antimicrobial peptides against a US strain of the rice pathogen Rhizoctonia solani. J Appl Microbiol 97, 169-180.
25. Orsi, N. (2004) The antimicrobial activity of lactoferrin: current status and perspectives. BioMetals 17, 189-196.
26. Osusky, M., Zhou, G., Osuska, L., Hancock, R.E., Kay, W.W. and Misra, S. (2000) Transgenic plants expressing cationic peptide chimeras exhibit broad-spectrum resistance to phytopathogens. Nat Biotechnol 18, 1162-1166.
27. Rao, A.G. (1995) Antimicrobial peptides. Mol Plant-Microbe Interact 8, 6-13.
28. Reed, J.D., Edwards, D.L. and Gonzalez, C.F. (1997) Synthetic peptide combinatorial libraries: a method for the identifi-cation of bioactive peptides against phytopathogenic fungi. Mol Plant-Microbe Interact 10, 537-549.
29. Rioux, D., Jacobi, V., Simard, M. and Hamelin, R.C. (2000) Structural changes of spores of tree fungal pathogens after treatment with the designed antimicrobial peptide D2A21. Can J Botany 78, 462-471.
30. Schibli, D.J., Hwang, P.M. and Vogel, H.J. (1999) The structure of the antimicrobial active center of lactoferricin B bound to sodium dodecyl sulfate micelles. FEBS Lett 446, 213-217.
31. Strom, M.B., Haug, B.E., Rekdal, O., Skar, M.L., Stensen, W. and Svendsen, J.S. (2002) Important structural features of 15-residue lactoferricin derivatives and methods for improvement of antimicrobial activity. Biochem Cell Biol 80, 65-74.
32. Tomita, M., Takase, M., Bellamy, W. and Shimamura, S. (1994) A review: the active peptide of lactoferrin. Acta Paediatr Jpn 36, 585-591.
33. Ueta, E., Tanida, T. and Osaki, T. (2001) A novel bovine lactoferrin peptide, FKCRRWQWRM, suppresses Candida cell growth and activates neutrophils. J Pept Res 57, 240-249.
34. Ulvatne, H., Haukland, H.H., Olsvik, O. and Vorland, L.H. (2001) Lactoferricin B causes depolarization of the cytoplasmic membrane of Escherichia coli ATCC 25922 and fusion of negatively charged liposomes. FEBS Lett 492, 62-65.
35. Ulvatne, H., Samuelsen, O., Haukland, H.H., Kramer, M. and Vorland, L.H. (2004) Lactoferricin B inhibits bacterial macromolecular synthesis in Escherichia coli and Bacillus subtilis. FEMS Microbiol Lett 237, 377-384.
36. Vogel, H.J., Schibli, D.J., Jing, W., Lohmeier-Vogel, E.M., Epand, R.F. and Epand, R.M. (2002) Towards a structurefunction analysis of bovine lactoferricin and related tryptophan- and arginine-containing peptides. Biochem Cell Biol 80, 49-63.
37. Wakabayashi, H., Abe, S., Teraguchi, S., Hayasawa, H. and Yamaguchi, H. (1998) Inhibition of hyphal growth of azole-resistant strains of Candida albicans by triazole antifungal agents in the presence of lactoferrin-related compounds. Antimicrob Agents Chemother 42, 1587-1591.
38. Wakabayashi, H., Matsumoto, H., Hashimoto, K., Teraguchi, S., Takase, M. and Hayasawa, H. (1999) N-Acylated and D enantiomer derivatives of a nonamer core peptide of Lactoferricin B showing improved antimicrobial activity. Antimicrob Agents Chemother 43, 1267-1269.
39. Zasloff, M. (2002) Antimicrobial peptides of multicellular organisms. Nature 415, 389-395.
40. Zhang, Z.Y., Coyne, D.P., Vidaver, A.K. and Mitra, A. (1998) Expression of human lactoferrin cDNA confers resistance to Ralstonia solanacearum in transgenic tobacco plants. Phytopathology 88, 730-734.