Synthesis and anti-tumor activity of a fluorinated analog of medroxyprogesterone acetate (MPA), 9α-fluoromedroxyprogesterone acetate (FMPA)

Chemical and Pharmaceutical Bulletin

Volumn 54, Issue 11, 2006, Pages 1567-1570

  Murata, Natsuko ^a   Fujimori, Shiho ^a   Ichihara, Yoshitatsu ^a   Sato, Yoshio ^a   Yamaji, Taketo ^a   Tsuboi, Hiroshi ^a   Uchida, Masayuki ^a   Suzuki, Hiroto ^a   Yamada, Masashi ^a   Oikawa, Tsutomu ^b   Nemoto, Hideo ^c   Nobuhiro, Junko ^d   Choshi, Tominari ^d   Hibino, Satoshi ^d  

^a MEIJI DAIRIES CORPORATION   (Japan)

^b KANAGAWA UNIVERSITY OF HUMAN SERVICES   (Japan)

^c UNIVERSITY OF TOYAMA   (Japan)

^d FUKUYAMA UNIVERSITY   (Japan)

Author keywords

9 fluoromedroxyprogesterone acetate; Anti angiogenic agent; Dimethylbenz a anthracene; Mammary carcinoma; Medroxyprogesterone acetate; Synthesis

Indexed keywords

9ALPHA FLUOROMEDROXYPROGESTERONE ACETATE; ANGIOGENESIS INHIBITOR; DEXTRIN; DIMETHYL BETA CYCLODEXTRIN; DIMETHYLBENZ[A]ANTHRACENE; MEDROXYPROGESTERONE ACETATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CARCINOMA; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; FLUORINATION; NONHUMAN;

ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; FLUORINE; MAMMARY NEOPLASMS, EXPERIMENTAL; MEDROXYPROGESTERONE 17-ACETATE; MOLECULAR CONFORMATION; RATS; RATS, SPRAGUE-DAWLEY; STEREOISOMERISM;

EID: 33750721303     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.54.1567     Document Type: Article

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