Extracellular serotonin changes in VLM during muscle contraction: Effects of 5-HT(1A)-receptor activation

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 273, Issue 6 42-6, 1997, Pages

  Asmundsson, Gudbjorn ^c   Caringi, Daryl ^c   Mokler, David J ^c   Kobayashi, Toshio ^c   Ishide, Takeshi ^a   Ally, Ahmmed ^b  

^a CHIBA UNIVERSITY   (Japan)

^b UNIVERSITY OF NEW ENGLAND   (United States)

^c NONE

Author keywords

Arterial blood pressure; Caudal ventrolateral medulla; Exercise pressor reflex; Heart rate; Rat; Rostral ventrolateral medulla

Indexed keywords

1 (2 METHOXYPHENYL) 4 (4 PHTHALIMIDOBUTYL)PIPERAZINE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; SEROTONIN; SEROTONIN 1A AGONIST; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEART RATE; MALE; MEAN ARTERIAL PRESSURE; MEDULLA OBLONGATA; MICRODIALYSIS; MUSCLE CONTRACTION; NERVE STIMULATION; NONHUMAN; PARALYSIS; PRIORITY JOURNAL; RAT; TIBIAL NERVE;

EID: 33750720367     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1997.273.6.h2899     Document Type: Article

References (14)

1. Adell, A., A. Carcellar, and F. Artigas. In vivo brain dialysis study of the somatodendritic release of serotonin in the raphe nuclei of the rat: effects of 8-hydroxy-2-(di-n-propylamino)tetralin. J. Neurochem. 60: 1673-1681, 1993.
2. 1A modulation of cardiovascular responses to tibial nerve stimulation-evoked muscle contraction. Am. J. Physiol. 272 (Regulatory Integrative Comp. Physiol. 41): R1020-R1027, 1997.
3. Barman, S. M., and G. L. Gebber. Axonal projection pattern of ventrolateral medullospinal sympathoexcitatory neurons. J. Neurophysiol. 53: 1551-1566, 1985.
4. Bauer, R. M., G. A. Iwamoto, and T. G. Waldrop. Ventrolateral medullary neurons modulate presser reflex to muscle contrac-tion. Am. J. Physiol. 257 (Regulatory Integrative Comp. Physiol 26): R1154-R1161, 1989.
5. Bauer, R. M., T. G. Waldrop, G. A. Iwamoto, and M. A. Holzwarth. Properties of ventrolateral medullary neurons that respond to muscle contraction. Brain Res. Bull. 28: 167-168, 1992.
6. Bowker, R. M., K. N. Westlund, and J. D. Coulter. Origins of serotonergic projections to the spinal cord in the rat: an immuno-cytochemical-retrograde transport study. Brain Res. 226: 187-199, 1981.
7. Callera, J. C., L. G. Bonagamba, C. Sevoz., R. Laguzzi, and B. H. Machado. Cardiovascular effects of microinjection of low doses of serotonin into the NTS of unanesthetized rats. Am. J. Physiol. 272 (Regulatory Integrative Comp. Physiol. 41): R1135-R1142, 1997.
8. Ciriello, J., M. M. Caverson, and C. Polosa. Function of the ventrolateral medulla in the control of circulation. Brain Res. Bull. 11: 359-391, 1986.
9. 1A-mediated facilitation of in vivo acetylcholine release in rat frontal cortex. Brain Res. 707: 320-323, 1996.
10. Coote, J. H. Bulbospinal serotonergic pathways in the control of blood pressure. J. Cardiovasc. Pharmacol. 15: S35-S41, 1990.
11. Coote, J. H., S. M. Hilton, and J. F. Perez-Gonzales. The reflex nature of the pressor response to muscular exercise. J. Physiol. (Lond.) 215: 789-804, 1971.
12. Dampney, R. A. L., and E. A. Moon. Role of ventrolateral medulla in vasomotor response to cerebral ischemia. Am. J. Physiol. 239 (Heart Circ. Physiol. 8): H349-H358, 1980.
13. Dedeogly, A., and L. A. Fisher. CNS actions of serotonin on cardiovascular function: nonadrenergic, noncholinergic mechanisms. Am. J. Physiol. 271 (Regulatory Integrative Comp. Physiol. 40): R569-R578, 1996.
14. Fozard, J. R., A. K. Mir, and D. N. Middlemiss. Cardiovascular response to 8-hydroxy-2-(di-n-propyl-amino)tetralin (8-OHDPAT) in the rat: site of action and pharmacological analysis. J. Cardiovasc. Pharmacol. 9: 328-347, 1987.