β-adrenergic dilation of conductance coronary arteries involves flow- dependent NO formation in conscious dogs

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 271, Issue 5 40-5, 1996, Pages

  Hamdad, Nadia ^a   Ming, Zhi ^a   Parent, Robert ^a   Lavallée, Michel ^a  

^a MONTREAL HEART INSTITUTE   (Canada)

Author keywords

conductance coronary vessels; endothelium derived relaxing factor; adrenergic receptors

Indexed keywords

GLYCERYL TRINITRATE; ISOPRENALINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PIRBUTEROL; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; ENZYME INHIBITOR;

ADRENERGIC TRANSMISSION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY DIAMETER; ARTERY DILATATION; ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY BLOOD FLOW; DOG; MEMBRANE CONDUCTANCE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; ARTERY; BIOSYNTHESIS; CORONARY ARTERY DISEASE; CORONARY BLOOD VESSEL; DRUG EFFECT; HOMEOSTASIS; PATHOPHYSIOLOGY; PHYSIOLOGY; VASODILATATION;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; ARTERIES; CORONARY CIRCULATION; CORONARY DISEASE; CORONARY VESSELS; DOGS; ENZYME INHIBITORS; HOMEOSTASIS; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; RECEPTORS, ADRENERGIC, BETA; VASODILATION;

EID: 33750715782     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1996.271.5.h1926     Document Type: Article

References (34)

1. 1-adrenergic action. Comp. Biochem. Physiol. 97C: 311-315, 1990.
2. Angus, J. A., T. M. Cocks, and K. Satoh. α2-adrenoceptors and endothelium-dependent relaxation in canine large arteries. Br. J. Pharmacol. 88: 767-777, 1986.
3. Béa, M.-L., B. Ghaleh, J.-F. Giudicelli, and A. Berdeaux. Lack of importance of NO in β-adrenoceptor-mediated relaxation of large epicardial canine coronary arteries. Br. J. Pharmacol. 111: 981-982, 1994.
4. Bernard, F., S. Jouquey, and G. Hamon. Study of the vasodilating activity of salbutamol on dog coronary arteries. Pharmacology 42: 246-251, 1991.
5. 2-selective adrenoceptor antagonist (ICI 118,551). J. Cardiovasc. Pharmacol. 5: 430-437, 1983.
6. Canty, J. M., Jr., and J. S. Schwartz. Nitric oxide mediates flow-dependent epicardial coronary vasodilation to changes in pulse frequency but not mean flow in conscious dogs. Circulation 89: 375-384, 1994.
7. Chu, A., D. E. Chambers, C.-C. Lin, W. D. Kuehl, and F. R. Cobb. Nitric oxide modulates epicardial coronary basal vasomotor tone in awake dogs. Am. J. Physiol. 258 (Heart Circ. Physiol. 27): H1250-H1254, 1990.
8. Cocks, T. M., and J. A. Angus. Endothelium-dependent relaxation of coronary arteries by noradrenaline and serotonin. Nature Lond. 305: 627-630, 1983.
9. Eckly, A. E., J.-C. Stoclet, and C. Lugnier. Isoprenaline induces endothelium-independent relaxation and accumulation of cyclic nucleotides in the rat aorta. Eur. J. Pharmacol. 271: 237-240, 1994.
10. Feigl, E. O. Coronary physiology. Physiol. Rev. 63: 1-205, 1983.
11. G-nitro-L-arginine methyl ester on vasodilator responses to acetylcholine, 5′-N-ethylcarboxamidoadenosine or salbutamol in conscious rats. Br. J. Pharmacol. 103: 1725-1732, 1991.
12. Ghaleh, B., M.-L. Béa, J.-L. Dubois-Randé, J.-F. Giudicelli, L. Hittinger, and A. Berdeaux. Endothelial modulation of β-adrenergic dilation of large coronary arteries in conscious dogs. Circulation 92: 2627-2635, 1995.
13. Glantz, S. A. Primer of Biostatistics (2nd. ed.). New York: McGraw-Hill, 1987, p. 245-277.
14. Graves, J., and L. Poston. β-Adrenoceptor agonist mediated relaxation of rat isolated resistance arteries: a role for the endothelium and nitric oxide. Br. J. Pharmacol. 108: 631-637, 1993.
15. Gray, D. W., and I. Marshall. Novel signal transduction pathway mediating endothelium-dependent β-adrenoceptor vasorelaxation in rat thoracic aorta. Br. J. Pharmacol. 107: 684-690, 1992.
16. Gwirtz, P. A. Construction and evaluation of a coronary catheter for chronic implantation in dogs. J. Appl. Physiol. 60: 720-726, 1986.
17. Hartley, C. J., and J. S. Cole. An ultrasonic pulsed Doppler system for measuring blood flow in small vessels. J. Appl. Physiol. 37: 626-629, 1974.
18. Holtz, J., U. Förstermann, U. Pohl, M. Giesler, and E. Baseenge. Flow-dependent, endothelium-mediated dilation of epicardial coronary arteries in conscious dogs: effects of cyclooxygenase inhibition. J. Cardiovasc. Pharmacol. 6: 1161-1169, 1984.
19. Jackson, W. F., and R. Busse. Elevated guanosine 3′: 5′-cyclic monophosphate mediates the depression of nitrovasodilator reactivity in endothelium-intact blood vessels. Naunyn-Schmiedeberg's Arch. Pharmacol. 344: 345-350, 1991.
20. Macdonald, P. S., P. N. Dubbin, and G. J. Dusting. β-adrenoceptors on endothelial cells do not influence release of relaxing factor in dog coronary arteries. Clin. Exp. Pharmacol. Physiol. 14: 525-534, 1987.
21. 2 adrenergic bronchodilator. J. Pharmacol. Exp. Ther. 207: 410-418, 1978.
22. Nakane, T., G. Tsujimoto, K. Hashimoto, and S. Chiba. Beta adrenoceptors in the canine large coronary arteries: beta-1 adrenoceptors predominate in vasodilation. J. Pharmacol. Exp. Ther. 245: 936-943, 1988.
23. Parent, R., M. Al-Obaidi, and M. Lavallée. Nitric oxide formation contributes to β-adrenergic dilation of resistance coronary vessels in conscious dogs. Circ. Res. 73: 241-251, 1993.
24. Parent, R., R. Paré, and M. Lavallée. Contribution of nitric oxide to dilation of resistance coronary vessels in conscious dogs. Am. J. Physiol. 262 (Heart Circ. Physiol. 31): H10-H16, 1992.
25. Rubanyi, G., and P. M. Vanhoutte. Endothelium-removal decreases relaxations of canine coronary arteries caused by β-adrenergic agonists and adenosine. J. Cardiovasc. Pharmacol. 7: 139-144, 1985.
26. Stephenson, J. A., and R. J. Summers. Autoradiographic analysis of receptors on vascular endothelium. Eur. J. Pharmacol. 134: 35-43, 1987.
27. Stewart, J. M., J. Wang, and T. H. Hintze. Role of EDRF in the regulation of shear rate in large coronary arteries in conscious dogs. J. Mol. Cell. Cardiol. 26: 1625-1633, 1994.
28. Toda, N., and T. Okamura. Beta adrenoceptor subtype in isolated human, monkey and dog epicardial coronary arteries. J. Pharmacol. Exp. Ther. 253: 518-524, 1990.
29. Van Bibber, R., O. Traub, K. Kroll, and E. O. Feigl. EDRF and norepinephrine-induced vasodilation in the canine coronary circulation. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H1973-H1981, 1995.
30. Vatner, D. E., D. R. Knight, C. J. Homcy, S. F. Vatner, and M. A. Young. Subtypes of β-adrenergic receptors in bovine coronary arteries. Circ. Res. 59: 463-473, 1986.
31. Vatner, S. F., T. H. Hintze, and P. Macho. Regulation of large coronary arteries by β-adrenergic mechanisms in the conscious dog. Circ. Res. 51: 56-66, 1982.
32. Wang, Y.-X., K. S. Poon, D. J. Randall, and C. C. Y. Pang. Endothelium-derived nitric oxide partially mediates salbutamol-induced vasodilatations. Eur. J. Pharmacol. 250: 335-340, 1993.
33. Winer, B. J. Statistical Principles in Experimental Design (2nd ed.). New York: McGraw-Hill, 1971, p. 514-603.
34. Yamabe, H., K. Okumura, H. Ishizaka, T. Tsuchiya, and H. Yasue. Role of endothelium-derived nitric oxide in myocardial reactive hyperemia. Am. J. Physiol. 263 (Heart Circ. Physiol. 32): H8-H14, 1992.