Determination of aristolochic acid in botanicals and dietary supplements by liquid chromatography with ultraviolet detection and by liquid chromatography/mass spectrometry: Single laboratory validation confirmation

Journal of AOAC International

Volumn 89, Issue 4, 2006, Pages 942-959

  Trujillo, William A ^a   Sorenson, Wendy R ^a   La Luzerne, Paul ^a   Austad, John W ^a   Sullivan, Darryl ^a  

^a 206 Carnegie Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODIVERSITY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUTRITION; ORGANIC SOLVENTS; ULTRAVIOLET DETECTORS;

ARISTOLOCHIC ACID; LINEAR REGRESSION; PARAMETER VARIATIONS; ULTRAVIOLET DETECTION;

CARBOXYLIC ACIDS;

ACETONITRILE; ACETONITRILE DERIVATIVE; ARISTOLOCHIC ACID; ARISTOLOCHIC ACID I; ION; METHANOL; WATER;

ARTICLE; CHEMISTRY; DIET SUPPLEMENTATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHODOLOGY; PLANT ROOT; REPRODUCIBILITY; TIME; ULTRAVIOLET RADIATION;

ACETONITRILES; ARISTOLOCHIC ACIDS; CHEMISTRY, ANALYTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; DIETARY SUPPLEMENTS; IONS; MASS SPECTROMETRY; METHANOL; PLANT ROOTS; REPRODUCIBILITY OF RESULTS; TIME FACTORS; ULTRAVIOLET RAYS; WATER;

EID: 33750710754     PISSN: 10603271     EISSN: None     Source Type: Journal    
DOI: 10.1093/jaoac/89.4.942     Document Type: Article

References (4)

1. U.S. Food and Drug Administration (2000) Letter to Health Care Professionals-FDA Concerned About Botanical Products, Including Dietary Supplements, Containing Aristolochic Acid, May 31, College Park, MD
2. The European Agency for the Evaluation of Medicinal Products, Evaluation of Medicines for Human Use (2000) Position Paper on the Risks Associated with the Use of Herbal Products Containing Aristolochia species, October 31, London, UK
3. Kite, G.C., Yule, M.A., Leon, C., & Simmonds, M.S.J. (2002) Rapid Commun. Mass Spectrom. 16, 585-590
4. Flurer, R.A., Jones, M.B., Vela, N., Ciolino, L.A., & Wolnick, K.A. Determination of Aristolochic Acid in Traditional Chinese Medicines and Dietary Supplements, marked DRAFT, No. 4212, U.S. Food and Drug Administration, Forensic Chemistry Center, Cincinnati, OH