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Volumn 123, Issue 11, 2006, Pages 819-830

Dlx5- and Dlx6-mediated chondrogenesis: Differential domain requirements for a conserved function

Author keywords

Chondrogenesis; Differentiation; Dlx5; Dlx6; Skeletal development; Transcription factor

Indexed keywords

HOMEODOMAIN PROTEIN; PROTEIN; TRANSCRIPTION FACTOR DLX5; TRANSCRIPTION FACTOR DLX6; UNCLASSIFIED DRUG;

EID: 33750696339     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mod.2006.08.005     Document Type: Article
Times cited : (27)

References (44)
  • 1
    • 0032872336 scopus 로고    scopus 로고
    • Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5
    • Acampora D., Merlo G.R., Paleari L., Zerega B., Postiglione M.P., Mantero S., et al. Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5. Development 126 (1999) 3795-3809
    • (1999) Development , vol.126 , pp. 3795-3809
    • Acampora, D.1    Merlo, G.R.2    Paleari, L.3    Zerega, B.4    Postiglione, M.P.5    Mantero, S.6
  • 2
    • 0036830491 scopus 로고    scopus 로고
    • The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6
    • Akiyama H., Chaboissier M.C., Martin J.F., Schedl A., and de Crombrugghe B. The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev. 16 (2002) 2813-2828
    • (2002) Genes Dev. , vol.16 , pp. 2813-2828
    • Akiyama, H.1    Chaboissier, M.C.2    Martin, J.F.3    Schedl, A.4    de Crombrugghe, B.5
  • 3
    • 23944472640 scopus 로고    scopus 로고
    • The molecular elements that underlie developmental evolution
    • Alonso C.R., and Wilkins A.S. The molecular elements that underlie developmental evolution. Nat. Rev. Genet. 6 (2005) 709-715
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 709-715
    • Alonso, C.R.1    Wilkins, A.S.2
  • 5
    • 0042526060 scopus 로고    scopus 로고
    • Dlx5 regulates chondrocyte differentiation at multiple stages
    • Bendall A.J., Hu G., Levi G., and Abate-Shen C. Dlx5 regulates chondrocyte differentiation at multiple stages. Int. J. Dev. Biol. 47 (2003) 335-344
    • (2003) Int. J. Dev. Biol. , vol.47 , pp. 335-344
    • Bendall, A.J.1    Hu, G.2    Levi, G.3    Abate-Shen, C.4
  • 6
    • 0034607664 scopus 로고    scopus 로고
    • Identification of a homeodomain binding element in the bone sialoprotein gene promoter that is required for its osteoblast-selective expression
    • Benson M.D., Bargeon J.L., Xiao G., Thomas P.E., Kim A., Cui Y., et al. Identification of a homeodomain binding element in the bone sialoprotein gene promoter that is required for its osteoblast-selective expression. J. Biol. Chem. 275 (2000) 13907-13917
    • (2000) J. Biol. Chem. , vol.275 , pp. 13907-13917
    • Benson, M.D.1    Bargeon, J.L.2    Xiao, G.3    Thomas, P.E.4    Kim, A.5    Cui, Y.6
  • 7
    • 6444245826 scopus 로고    scopus 로고
    • Jaw transformation with gain of symmetry after Dlx5/Dlx6 inactivation: mirror of the past?
    • Beverdam A., Merlo G.R., Paleari L., Mantero S., Genova F., Barbieri O., et al. Jaw transformation with gain of symmetry after Dlx5/Dlx6 inactivation: mirror of the past?. Genesis 34 (2002) 221-227
    • (2002) Genesis , vol.34 , pp. 221-227
    • Beverdam, A.1    Merlo, G.R.2    Paleari, L.3    Mantero, S.4    Genova, F.5    Barbieri, O.6
  • 8
    • 0033747645 scopus 로고    scopus 로고
    • Identification and developmental expression of three Distal-less hmeobox containing genes in the ascidian Ciona intestinalis
    • Caracciolo A., Di Gregorio A., Aniello F., Di Lauro R., and Branno M. Identification and developmental expression of three Distal-less hmeobox containing genes in the ascidian Ciona intestinalis. Mech. Dev. 99 (2000) 173-176
    • (2000) Mech. Dev. , vol.99 , pp. 173-176
    • Caracciolo, A.1    Di Gregorio, A.2    Aniello, F.3    Di Lauro, R.4    Branno, M.5
  • 9
    • 0034625265 scopus 로고    scopus 로고
    • Endless forms: the evolution of gene regulation and morphological diversity
    • Carroll S.B. Endless forms: the evolution of gene regulation and morphological diversity. Cell 101 (2000) 577-580
    • (2000) Cell , vol.101 , pp. 577-580
    • Carroll, S.B.1
  • 10
    • 0029743136 scopus 로고    scopus 로고
    • Dlx5 and Dlx6: an evolutionary conserved pair of murine homeobox genes expressed in the embryonic skeleton
    • Chen X., Li X., Wang W., and Lufkin T. Dlx5 and Dlx6: an evolutionary conserved pair of murine homeobox genes expressed in the embryonic skeleton. Ann. N. Y. Acad. Sci. 785 (1996) 38-47
    • (1996) Ann. N. Y. Acad. Sci. , vol.785 , pp. 38-47
    • Chen, X.1    Li, X.2    Wang, W.3    Lufkin, T.4
  • 11
    • 0032824045 scopus 로고    scopus 로고
    • Dlx5 regulates regional development of the branchial arches and sensory capsules
    • Depew M.J., Liu J.K., Long J.E., Presley R., Meneses J.J., Pedersen R.A., et al. Dlx5 regulates regional development of the branchial arches and sensory capsules. Development 126 (1999) 3831-3846
    • (1999) Development , vol.126 , pp. 3831-3846
    • Depew, M.J.1    Liu, J.K.2    Long, J.E.3    Presley, R.4    Meneses, J.J.5    Pedersen, R.A.6
  • 12
    • 0037064154 scopus 로고    scopus 로고
    • Specification of jaw subdivisions by Dlx genes
    • Depew M.J., Lufkin T., and Rubenstein J.L. Specification of jaw subdivisions by Dlx genes. Science 298 (2002) 381-385
    • (2002) Science , vol.298 , pp. 381-385
    • Depew, M.J.1    Lufkin, T.2    Rubenstein, J.L.3
  • 13
    • 0030057818 scopus 로고    scopus 로고
    • Identification of a TAAT-containing motif required for high level expression of the COL1A1 promoter in differentiated osteoblasts of transgenic mice
    • Dodig M., Kronenberg M.S., Bedalov A., Kream B.E., Gronowicz G., Clark S.H., et al. Identification of a TAAT-containing motif required for high level expression of the COL1A1 promoter in differentiated osteoblasts of transgenic mice. J. Biol. Chem. 271 (1996) 16422-16429
    • (1996) J. Biol. Chem. , vol.271 , pp. 16422-16429
    • Dodig, M.1    Kronenberg, M.S.2    Bedalov, A.3    Kream, B.E.4    Gronowicz, G.5    Clark, S.H.6
  • 14
    • 0345192350 scopus 로고    scopus 로고
    • DLX-1, DLX-2, and DLX-5 expression define distinct stages of basal forebrain differentiation
    • Eisenstat D.D., Liu J.K., Mione M., Zhong W., Yu G., Anderson S.A., et al. DLX-1, DLX-2, and DLX-5 expression define distinct stages of basal forebrain differentiation. J. Comp. Neurol. 414 (1999) 217-237
    • (1999) J. Comp. Neurol. , vol.414 , pp. 217-237
    • Eisenstat, D.D.1    Liu, J.K.2    Mione, M.3    Zhong, W.4    Yu, G.5    Anderson, S.A.6
  • 15
    • 0036941784 scopus 로고    scopus 로고
    • Dlx5 is a positive regulator of chondrocyte differentiation during endochondral ossification
    • Ferrari D., and Kosher R.A. Dlx5 is a positive regulator of chondrocyte differentiation during endochondral ossification. Dev. Biol. 252 (2002) 257-270
    • (2002) Dev. Biol. , vol.252 , pp. 257-270
    • Ferrari, D.1    Kosher, R.A.2
  • 16
    • 0029095013 scopus 로고
    • The expression pattern of the Distal-less homeobox-containing gene Dlx-5 in the developing chick limb bud suggests its involvement in apical ectodermal ridge activity, pattern formation, and cartilage differentiation
    • Ferrari D., Sumoy L., Gannon J., Sun H., Brown A.M., Upholt W.B., et al. The expression pattern of the Distal-less homeobox-containing gene Dlx-5 in the developing chick limb bud suggests its involvement in apical ectodermal ridge activity, pattern formation, and cartilage differentiation. Mech. Dev. 52 (1995) 257-264
    • (1995) Mech. Dev. , vol.52 , pp. 257-264
    • Ferrari, D.1    Sumoy, L.2    Gannon, J.3    Sun, H.4    Brown, A.M.5    Upholt, W.B.6
  • 17
    • 0037397910 scopus 로고    scopus 로고
    • Regulatory roles of conserved intergenic domains in vertebrate Dlx bigene clusters
    • Ghanem N., Jarinova O., Amores A., Long Q., Hatch G., Park B.K., et al. Regulatory roles of conserved intergenic domains in vertebrate Dlx bigene clusters. Genome Res. 13 (2003) 533-543
    • (2003) Genome Res. , vol.13 , pp. 533-543
    • Ghanem, N.1    Jarinova, O.2    Amores, A.3    Long, Q.4    Hatch, G.5    Park, B.K.6
  • 18
    • 4744340414 scopus 로고    scopus 로고
    • Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene
    • Hassan M.Q., Javed A., Morasso M.I., Karlin J., Montecino M., van Wijnen A.J., et al. Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene. Mol. Cell. Biol. 24 (2004) 9248-9261
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 9248-9261
    • Hassan, M.Q.1    Javed, A.2    Morasso, M.I.3    Karlin, J.4    Montecino, M.5    van Wijnen, A.J.6
  • 19
    • 0032938895 scopus 로고    scopus 로고
    • Regulation and role of Sox9 in cartilage formation
    • Healy C., Uwanogho D., and Sharpe P.T. Regulation and role of Sox9 in cartilage formation. Dev. Dyn. 215 (1999) 69-78
    • (1999) Dev. Dyn. , vol.215 , pp. 69-78
    • Healy, C.1    Uwanogho, D.2    Sharpe, P.T.3
  • 20
    • 19944431653 scopus 로고    scopus 로고
    • Transcriptome analysis for the chicken based on 19,626 finished cDNA sequences and 485,337 expressed sequence tags
    • Hubbard S.J., Grafham D.V., Beattie K.J., Overton I.M., McLaren S.R., Croning M.D., et al. Transcriptome analysis for the chicken based on 19,626 finished cDNA sequences and 485,337 expressed sequence tags. Genome Res. 15 (2005) 174-183
    • (2005) Genome Res. , vol.15 , pp. 174-183
    • Hubbard, S.J.1    Grafham, D.V.2    Beattie, K.J.3    Overton, I.M.4    McLaren, S.R.5    Croning, M.D.6
  • 21
    • 0023265819 scopus 로고
    • Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors
    • Hughes S.H., Greenhouse J.J., Petropoulos C.J., and Sutrave P. Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors. J. Virol. 61 (1987) 3004-3012
    • (1987) J. Virol. , vol.61 , pp. 3004-3012
    • Hughes, S.H.1    Greenhouse, J.J.2    Petropoulos, C.J.3    Sutrave, P.4
  • 22
    • 0034740591 scopus 로고    scopus 로고
    • TGFβ and BMP-2 activation of the OPN promoter: roles of smad- and hox-binding elements
    • Hullinger T.G., Pan Q., Viswanathan H.L., and Somerman M.J. TGFβ and BMP-2 activation of the OPN promoter: roles of smad- and hox-binding elements. Exp. Cell Res. 262 (2001) 69-74
    • (2001) Exp. Cell Res. , vol.262 , pp. 69-74
    • Hullinger, T.G.1    Pan, Q.2    Viswanathan, H.L.3    Somerman, M.J.4
  • 24
    • 0003080791 scopus 로고    scopus 로고
    • Dlx genes encode DNA-binding proteins that are expressed in an overlapping and sequential pattern during basal ganglia differentiation
    • Liu J.K., Ghattas I., Liu S., Chen S., and Rubenstein J.L. Dlx genes encode DNA-binding proteins that are expressed in an overlapping and sequential pattern during basal ganglia differentiation. Dev. Dyn. 210 (1997) 498-512
    • (1997) Dev. Dyn. , vol.210 , pp. 498-512
    • Liu, J.K.1    Ghattas, I.2    Liu, S.3    Chen, S.4    Rubenstein, J.L.5
  • 25
    • 0030700485 scopus 로고    scopus 로고
    • Radical alterations in the roles of homeobox genes during echinoderm evolution
    • Lowe C.J., and Wray G.A. Radical alterations in the roles of homeobox genes during echinoderm evolution. Nature 389 (1997) 718-721
    • (1997) Nature , vol.389 , pp. 718-721
    • Lowe, C.J.1    Wray, G.A.2
  • 26
    • 17644423924 scopus 로고    scopus 로고
    • Dlx2 over-expression regulates cell adhesion and mesenchymal condensation in ectomesenchyme
    • McKeown S.J., Newgreen D.F., and Farlie P.G. Dlx2 over-expression regulates cell adhesion and mesenchymal condensation in ectomesenchyme. Dev. Biol. 281 (2005) 22-37
    • (2005) Dev. Biol. , vol.281 , pp. 22-37
    • McKeown, S.J.1    Newgreen, D.F.2    Farlie, P.G.3
  • 27
    • 19744378342 scopus 로고    scopus 로고
    • The homeobox transcription factor Barx2 regulates chondrogenesis during limb development
    • Meech R., Edelman D.B., Jones F.S., and Makarenkova H.P. The homeobox transcription factor Barx2 regulates chondrogenesis during limb development. Development 132 (2005) 2135-2146
    • (2005) Development , vol.132 , pp. 2135-2146
    • Meech, R.1    Edelman, D.B.2    Jones, F.S.3    Makarenkova, H.P.4
  • 30
    • 0031104994 scopus 로고    scopus 로고
    • SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse
    • Ng L.-J., Wheatley S., Muscat G.E.O., Conway-Campbell J., Bowles J., Wright E., et al. SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse. Dev. Biol. 183 (1997) 108-121
    • (1997) Dev. Biol. , vol.183 , pp. 108-121
    • Ng, L.-J.1    Wheatley, S.2    Muscat, G.E.O.3    Conway-Campbell, J.4    Bowles, J.5    Wright, E.6
  • 31
    • 1942518259 scopus 로고    scopus 로고
    • Intergenic enhancers with distinct activities regulate Dlx gene expression in the mesenchyme of the branchial arches
    • Park B.K., Sperber S.M., Choudhury A., Ghanem N., Hatch G.T., Sharpe P.T., et al. Intergenic enhancers with distinct activities regulate Dlx gene expression in the mesenchyme of the branchial arches. Dev. Biol. 268 (2004) 532-545
    • (2004) Dev. Biol. , vol.268 , pp. 532-545
    • Park, B.K.1    Sperber, S.M.2    Choudhury, A.3    Ghanem, N.4    Hatch, G.T.5    Sharpe, P.T.6
  • 32
    • 0035380110 scopus 로고    scopus 로고
    • The coding region of the human DLX6 gene contains a polymorphic CAG/CCG repeat
    • Pfeffer U., Ferro P., Pavia V., Trombino S., Delleva R., Merlo G., et al. The coding region of the human DLX6 gene contains a polymorphic CAG/CCG repeat. Int. J. Oncol. 18 (2001) 1293-1297
    • (2001) Int. J. Oncol. , vol.18 , pp. 1293-1297
    • Pfeffer, U.1    Ferro, P.2    Pavia, V.3    Trombino, S.4    Delleva, R.5    Merlo, G.6
  • 33
    • 0030955889 scopus 로고    scopus 로고
    • Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches
    • Qiu M., Bulfone A., Ghattas I., Meneses J.J., Christensen L., Sharpe P.T., et al. Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Dev. Biol. 185 (1997) 165-184
    • (1997) Dev. Biol. , vol.185 , pp. 165-184
    • Qiu, M.1    Bulfone, A.2    Ghattas, I.3    Meneses, J.J.4    Christensen, L.5    Sharpe, P.T.6
  • 34
    • 0028808204 scopus 로고
    • Null mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation in the forebrain
    • Qiu M., Bulfone A., Martinez S., Meneses J.J., Shimamura K., Pedersen R.A., et al. Null mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation in the forebrain. Genes Dev. 9 (1995) 2523-2538
    • (1995) Genes Dev. , vol.9 , pp. 2523-2538
    • Qiu, M.1    Bulfone, A.2    Martinez, S.3    Meneses, J.J.4    Shimamura, K.5    Pedersen, R.A.6
  • 35
    • 0036558218 scopus 로고    scopus 로고
    • The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development
    • Robledo R.F., Rajan L., Li X., and Lufkin T. The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. Genes Dev. 16 (2002) 1089-1101
    • (2002) Genes Dev. , vol.16 , pp. 1089-1101
    • Robledo, R.F.1    Rajan, L.2    Li, X.3    Lufkin, T.4
  • 38
    • 0022239577 scopus 로고
    • Regulation of cytomegalovirus gene expression: alpha and beta promoters are trans activated by viral functions in permissive human fibroblasts
    • Spaete R.R., and Mocarski E.S. Regulation of cytomegalovirus gene expression: alpha and beta promoters are trans activated by viral functions in permissive human fibroblasts. J. Virol. 56 (1985) 135-143
    • (1985) J. Virol. , vol.56 , pp. 135-143
    • Spaete, R.R.1    Mocarski, E.S.2
  • 40
    • 0037266674 scopus 로고    scopus 로고
    • The role of gene duplication in the evolution and function of the vertebrate Dlx/distal-less bigene clusters
    • Sumiyama K., Irvine S.Q., and Ruddle F.H. The role of gene duplication in the evolution and function of the vertebrate Dlx/distal-less bigene clusters. J. Struct. Funct. Genomics 3 (2003) 151-159
    • (2003) J. Struct. Funct. Genomics , vol.3 , pp. 151-159
    • Sumiyama, K.1    Irvine, S.Q.2    Ruddle, F.H.3
  • 41
    • 0037388173 scopus 로고    scopus 로고
    • Regulation of Dlx3 gene expression in visceral arches by evolutionarily conserved enhancer elements
    • Sumiyama K., and Ruddle F.H. Regulation of Dlx3 gene expression in visceral arches by evolutionarily conserved enhancer elements. Proc. Natl. Acad. Sci. (USA) 100 (2003) 4030-4034
    • (2003) Proc. Natl. Acad. Sci. (USA) , vol.100 , pp. 4030-4034
    • Sumiyama, K.1    Ruddle, F.H.2
  • 42
    • 0028129062 scopus 로고
    • rDlx, a novel distal-less-like homeoprotein is expressed in developing cartilages and discrete neuronal tissues
    • Zhao G.Q., Zhao S., Zhou X., Eberspaecher H., Solursh M., and deCrombrugghe B. rDlx, a novel distal-less-like homeoprotein is expressed in developing cartilages and discrete neuronal tissues. Dev. Biol. 164 (1994) 37-51
    • (1994) Dev. Biol. , vol.164 , pp. 37-51
    • Zhao, G.Q.1    Zhao, S.2    Zhou, X.3    Eberspaecher, H.4    Solursh, M.5    deCrombrugghe, B.6
  • 43
    • 0034054756 scopus 로고    scopus 로고
    • Expression of Dlx genes during the development of the murine dentition
    • Zhao Z., Stock D.W., Buchanan A.V., and Weiss K.M. Expression of Dlx genes during the development of the murine dentition. Dev. Genes Evol. 210 (2000) 270-275
    • (2000) Dev. Genes Evol. , vol.210 , pp. 270-275
    • Zhao, Z.1    Stock, D.W.2    Buchanan, A.V.3    Weiss, K.M.4
  • 44
    • 31344456710 scopus 로고    scopus 로고
    • Dlx3 is expressed in the ventral forebrain of chicken embryos: implications for the evolution of the Dlx gene family
    • Zhu H., and Bendall A.J. Dlx3 is expressed in the ventral forebrain of chicken embryos: implications for the evolution of the Dlx gene family. Int. J. Dev. Biol. 50 (2006) 71-75
    • (2006) Int. J. Dev. Biol. , vol.50 , pp. 71-75
    • Zhu, H.1    Bendall, A.J.2


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