Mechanical stimulation is not responsible for activation of gastrointestinal afferents during ischemia

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 272, Issue 1 41-1, 1997, Pages

  Pan, Hui Lin ^a,b   Zeisse, Zachary B ^a   Longhurst, John C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

atropine; cats; gastrointestinal motility; nociceptors; splanchnic circulation

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAT; CONTROLLED STUDY; FEMALE; GASTROINTESTINAL MOTILITY; INTESTINE ISCHEMIA; INTESTINE PRESSURE; MALE; MECHANICAL STIMULATION; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; SENSORY NERVE;

EID: 33750682037     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1997.272.1.h99     Document Type: Article

References (21)

1. 2 on intestinal blood flow, tonus, and motility. Am. J. Physiol. 189: 541-547, 1957.
2. Burks, T. F. Actions of drugs on gastrointestinal motility. In: Physiology of the Gastrointestinal Tract (2nd ed.), edited by L. R. Johnson. New York: Raven, 1987, p. 723-743.
3. Cabot, R. M., and S. Kohatsu. The effects of ischemia on the electrical and contractile activities of the canine small intestine. Am. J. Surg. 136: 242-246, 1978.
4. Chou, C. C. Relationship between intestinal blood flow, and motility. Annu. Rev. Physiol. 44: 29-42, 1982.
5. Chou, C. C., and R. H. Gallavan. Blood flow and intestinal motility. Federation Proc. 41: 2090-2095, 1982.
6. Dixon, J. A., C. G. Harman, R. L. Nichols, and E. Englert. Intestinal motility following luminal and vascular occlusion of the small intestine. Gastroenterology 58: 673-678, 1970.
7. Fasth, S., and L. Hulten. The efffect of bradykinin on intestinal motility and blood flow. Acta Chir. Scand. 139: 699-705, 1973.
8. Gasser, H. S. Unmedullated fibers originating in dorsal root ganglia. J. Gen. Physiol. 33: 651-690, 1951.
9. Guisan, Y. J., A. Hreno, and F. N. Gurd. Effect of acute ischemia on the motility of the small bowel in the awake dog. Eur. Surg. Res. 7: 23-33, 1975.
10. Haupt, P., W. Jänig, and W. Kohler. Response pattern of visceral afferent fibers, supplying the colon, upon chemical and mechanical stimuli. Pfluegers Arch. 398, 41-47, 1983.
11. Kock, N. G. An experimental analysis of mechanisms engaged in reflex inhibition of intestinal motility. Acta Physiol. Scan. Suppl. 164: 1-54, 1967.
12. Kuo, D. C., and W. C. De Groat. Primary afferent projections of the major splanchnic nerve to the spinal cord and gracile nucleus of the cat. J. Comp. Neurol. 231: 421-434, 1985.
13. Longhurst, J. C. Chemosensitive abdominal visceral afferents. In: Proceedings of Visceral Pain Symposium, edited by G. F. Gebhart. Seattle, WA:International Association for the Study of Pain Press, 1995, p. 99-132.
14. Longhurst, J. C., D. M. Rotto, M. P. Kaufman, and G. L. Stahl. Ischemically sensitive abdominal visceral afferents: response to cyclooxygenase blockade. Am. J. Physiol. 261 (Heart Circ. Physiol. 30): H2075-H2081, 1991.
15. Longhurst, J. C., H. L. Spilker, and G. A. Ordway. Cardiovascular reflexes elicited by passive gastric distension in anesthetized cats. Am. J. Physiol. 240 (Heart Circ. Physiol. 9): H539-H545, 1981.
16. McDougal, M. D., and G. B. West. The inhibition of the peristaltic reflex by sympathomimetic amines. Br. J. Pharmacol. 9: 131-137, 1954.
17. Meissner, A., K. L. Bowles, and S. K. Sarna. Effects of ambient and stagnant hypoxia on the mechanical and electrical activity of the canine upper jejunum. Can. J. Surg. 19: 316-321, 1976.
18. Ordway, G. A., K. R. Boheler, and J. C. Longhurst. Stimulating intestinal afferents reflexly activates cardiovascular system in cats. Am. J. Physiol. 254 (Heart Circ. Physiol. 23): H354-H360, 1988.
19. Pan, H.-L., and J. C. Longhurst. Ischemia-sensitive sympathetic afferents innervating the gastrointestinal tract function as nociceptors in cats. J. Physiol. Lond. 492.3: 841-850, 1996.
20. Pan, H.-L., G. L. Stahl, and J. C. Longhurst. Differential effect of 5- and 15-lipoxygenase products on ischemically sensitive abdominal visceral afferents. Am. J. Physiol. 269 (Heart Circ. Physiol. 38): H96-H105, 1995.
21. Pan, H.-L., G. L. Stahl, S. V. Rendig, O. A. Carretero, and J. C. Longhurst. Endogenous bradykinin stimulates ischemically sensitive abdominal visceral C fiber afferents through kinin B 2 receptors. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H2398-H2406, 1994.