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Volumn 47, Issue 50, 2006, Pages 8973-8976

A convenient microwave-assisted arylstannane generation-Stille coupling protocol

Author keywords

[No Author keywords available]

Indexed keywords

PALLADIUM; PYRIDINE; TIN DERIVATIVE;

EID: 33750623865     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2006.10.015     Document Type: Article
Times cited : (7)

References (32)
  • 3
    • 0012397313 scopus 로고
    • For reviews see:
    • For reviews see:. Snieckus V. Chem. Rev. 90 (1990) 879-933
    • (1990) Chem. Rev. , vol.90 , pp. 879-933
    • Snieckus, V.1
  • 9
    • 84985570392 scopus 로고
    • For reviews of the Stille reaction see:
    • For reviews of the Stille reaction see:. Stille J.K. Angew. Chem., Int. Ed. Engl. 25 (1986) 508-524
    • (1986) Angew. Chem., Int. Ed. Engl. , vol.25 , pp. 508-524
    • Stille, J.K.1
  • 13
    • 33750630394 scopus 로고    scopus 로고
    • Astles, P. C.; Baker, S. R.; Keenan, M.; Vernier, J. M.; Sanderson, A. J.; Cube, R. V.; Martinez-Perez, J. A.; Maeto Herranz, A. I.; Dell, C. P.; Gutierrez, S.; Prietro, L.; Smith, C. W. WO 2003062235, Modulators of Acetylcholine Receptors; Chem. Abstr. 2003, 139, 149805. This work has been in part presented at YCI XIII, London, UK and at ASCMC Moscow 04.
  • 25
    • 33750612519 scopus 로고    scopus 로고
    • note
    • CEM Discovery. Multimode cavity system which continuously adjusts the applied wattage to maintain the desired temperature.
  • 26
    • 33750628413 scopus 로고    scopus 로고
    • note
    • 3) yielding 2 as a light brown solid (587 mg, 79% yield).
  • 27
    • 33750622456 scopus 로고    scopus 로고
    • note
    • 4 in toluene.
  • 28
    • 33750628729 scopus 로고    scopus 로고
    • note
    • 17 under nitrogen. The tube was closed, positioned in the microwave cavity and irradiated at 200 W for the given times. After allowing the tube to cool to room temperature within the microwave cavity for a couple of minutes, the crude mixture was concentrated and purified by flash column chromatography.
  • 29
    • 33750627289 scopus 로고    scopus 로고
    • note
    • The reactions were performed in a heavy-walled Pyrex tube equipped with a sealable metal cap and silicon septum. The reaction volume filled no more than two thirds of the total volume, thereby allowing space for pressure build-up during the microwave treatment.
  • 31
    • 33750634115 scopus 로고    scopus 로고
    • note
    • Under the conditions described, LCMS showed no sign of 10 after 2 h of conventional reflux; an aliquot was then heated in the microwave (110 °C/200 W, 5 min) after which LCMS showed full consumption of 4 and formation of 10.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.