Differential transcription profiles in Trypanosoma cruzi associated with clinical forms of Chagas disease: Maxicircle NADH dehydrogenase subunit 7 gene truncation in asymptomatic patient isolates

Molecular and Biochemical Parasitology

Volumn 150, Issue 2, 2006, Pages 236-248

  Baptista, Cassio S ^a   Vêncio, Ricardo Z N ^a   Abdala, Sarah ^a   Carranza, Julio César ^a,b   Westenberger, Scott J ^c   Silva, Marcelo N ^a   Pereira, Carlos A de B ^a   Galvão, Lúcia M C ^d   Gontijo, Eliane D ^d   Chiari, Egler ^d   Sturm, Nancy R ^c   Zingales, Bianca ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSIDAD DEL TOLIMA   (Colombia)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

Diagnosis; DNA microarrays; Human strains; Mitochondrial complex I; NADH dehydrogenase subunit 7; Tryparedoxin

Indexed keywords

CYCLOPHILIN; PROTEINASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

ADOLESCENT; ADULT; ARTICLE; CHAGAS DISEASE; CLINICAL ARTICLE; ELECTRON TRANSPORT; FEMALE; GENE DELETION; GENE STRUCTURE; GENETICS; HUMAN; MALE; MICROARRAY ANALYSIS; MITOCHONDRION; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRYPANOSOMA CRUZI;

ADOLESCENT; ADULT; ANIMALS; CHAGAS CARDIOMYOPATHY; CHAGAS DISEASE; DNA, KINETOPLAST; FEMALE; GENE DELETION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NADH DEHYDROGENASE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTOZOAN PROTEINS; TRYPANOSOMA CRUZI;

TRYPANOSOMA CRUZI;

EID: 33750622762     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2006.08.008     Document Type: Article

References (43)

1. WHO Expert Committee on the Control of Chagas Disease. Second report. Geneva: World Health Organization;2002.
2. Campbell D.A., Westenberger S.J., and Sturm N.R. The determinants of Chagas disease: connecting parasite and host genetics. Curr Mol Med 4 (2004) 549-562
3. Anonymous recommendations from a satellite meeting. Mem Inst Oswaldo Cruz 94 (1999) 429-432
4. Brisse S., Barnabé C., and Tibayrenc M. Identification of six Trypanosoma cruzi phylogenetic lineages by random amplified polymorphic DNA and multilocus enzyme electrophoresis. Int J Parasitol 30 (2000) 35-44
5. Westenberger S.J., Barnabé C., Campbell D.A., and Sturm N.R. Two hybridization events define the population structure of Trypanosoma cruzi. Genetics 171 (2005) 527-543
6. Zingales B., Souto R.P., Mangia R.H., et al. American Trypanosomiasis in Brazil based on dimorphism of rRNA and mini-exon sequences. Int J Parasitol 28 (1998) 105-112
7. Vago A.R., Andrade L.O., Leite A.A., et al. Genetic characterization of Trypanosoma cruzi directly from tissues of patients with chronic Chagas disease. Am J Pathol 156 (2000) 1805-1809
8. Simpson L., Sbicego S., and Aphasizhev R. Uridine insertion/deletion RNA editing in trypanosome mitochondria: a complex business. RNA 9 (2003) 265-276
9. Westenberger S.J., Cerqueira G.C., El-Sayed N.M., Zingales B., Campbell D.A., and Sturm N.R. Trypanosoma cruzi mitochondrial maxicircles display species- and strain-specific variation and possess a conserved element in the non-coding region. BMC Genomics 7 (2006) 60
10. Machado C.A., and Ayala F.J. Nucleotide sequences provide evidence of genetic exchange among distantly related lineages of Trypanosoma cruzi. Proc Natl Acad Sci USA 98 (2001) 7396-7401
11. Brisse S., Henriksson J., Barnabé C., et al. Evidence for genetic exchange and hybridization in Trypanosoma cruzi based on nucleotide sequences and molecular karyotype. Infect Genet Evol 2 (2003) 173-183
12. Dost C.K., Saiva J., Monesi N., Zentgraf U., Engels W., and Albuquerque S. SIX Trypanosoma cruzi strains characterized by specific gene expression patterns. Parasitol Res 94 (2004) 134-140
13. Baptista C.S., Vêncio R.Z.N., Abdala S., et al. DNA microarrays for comparative genomics and analysis of gene expression in Trypanosoma cruzi. Mol Biochem Parasitol 138 (2004) 183-194
14. Souto R.P., Fernandes O., Macedo A.M., Campbell D.A., and Zingales B. DNA markers define two major phylogenetic lineages of Trypanosoma cruzi. Mol Biochem Parasitol 83 (1996) 141-152
15. Zingales B., Abuin G., Romanha A.J., Chiari E., and Colli W. Surface antigens of stocks and clones of Trypanosoma cruzi isolated from humans. Acta Trop 41 (1984) 5-16
16. Ürmenyi T.P., Bonaldo M.F., Soares M.B., and Rondinelli E. Construction of a normalized cDNA library for the Trypanosoma cruzi Genome Project. J Eukaryot Microbiol 46 (1999) 542-544
17. Darocha W.D., Bartholomeu D.C., Macêdo C.D.S., et al. Characterization of cDNA clones encoding ribonucleoprotein antigens expressed in Trypanosoma cruzi amastigotes. Parasitol Res 88 (2002) 292-300
18. Huang X., and Madan A. CAP3: a DNA sequence assembly program. Genome Res 9 (1999) 868-877
19. Edgar R., Domrachev M., and Lash A.E. Gene expression omnibus: NCBI gene expression and hybridisation array data repository. Nucleic Acids Res 30 (2002) 207-210
20. Brazma A., Hingamp P., Quackenbush J., et al. Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. Nat Genet 29 (2001) 365-371
21. Duda R.O., Hart P.E., and Stork D.G. Pattern classification. 2nd ed. (2000), Wiley/Interscience
22. Vêncio R.Z.N., Brentani H., Patrão D.F.C., and Pereira C.A.B. Bayesian model accounting for within-class biological variability in SAGE analysis. BMC Bioinform 5 (2004) 119
23. Vêncio R.Z.N., Patrão D., Baptista C.S., Pereira C.d.B., and Zingales B. BayBoots: a model-free Bayesian tool to identify class markers from gene expression data. Genet Mol Res 5 (2006) 138-142
24. Medina-Acosta G., and Cross G.A.M. Rapid isolation of DNA from trypanosomatid protozoa using a simple 'mini-prep' procedure. Mol Biochem Parasitol 59 (1993) 327-330
25. Gonçalves A.M., Nehme N.S., and Morel C.M. An improved silver staining procedure for schizodeme analysis in polyacrylamide gradient gels. Mem Inst Oswaldo Cruz 85 (1990) 101-106
26. Duncan R. DNA microarray analysis of protozoan parasite gene expression: outcomes correlate with mechanisms of regulation. TRENDS Parasitol 5 (2004) 211-215
27. Westenberger S.J., Sturm N.R., and Campbell D.A. Trypanosoma cruzi 5S rRNA arrays define five groups and indicate the geographic origins of an ancestor of the heterozygous hybrids. Int J Parasitol 36 (2006) 337-346
28. Koslowsky D.J., Bhat G.J., Perrollaz A.L., Feagin J.E., and Stuart K. The MURF3 gene of T. brucei contains multiple domains of extensive editing and is homologous to a subunit of NADH dehydrogenase. Cell 62 (1990) 901-911
29. Heazlewood J.L., Howell K.A., and Millar A.H. Mitochondrial complex I from Arabidopsis and rice: orthologs of mammalian and fungal components coupled with plant-specific subunits. Biochim Biophys Acta 1604 (2003) 159-169
30. Gabler L., Herz U., Liddell A., et al. The 42.5 kDa subunit of the NADH: ubiquinone oxidoreductase (complex I) in higher plants is encoded by the mitochondrial nad7 gene. Mol Gen Genet 244 (1994) 33-40
31. Cazzulo J.J. Intermediate metabolism in Trypanosoma cruzi. J Bioenerg Biomembr 26 (1994) 157-164
32. Tielens A.G., and Van Hellemond. Reply. Parasitol Today 15 (1999) 347-348
33. Votyakova T.V., and Reynolds I.J. DeltaPsi(m)-dependent and -independent production of reactive oxygen species by rat brain mitochondria. J Neurochem 79 (2001) 266-277
34. Muller F.L., Liu Y., and Remmen V.L. Complex III releases superoxide to both sides of the inner mitochondrial membrane. J Biol Chem 47 (2004) 49064-49073
35. Boveris A., and Stoppani A.O. Hydrogen peroxide generation in Trypanosoma cruzi. Experientia 33 (1977) 1306-1308
36. Docampo R., and Moreno S.N. Free radical metabolism of antiparasitic agents. Fed Proc 45 (1986) 2471-2476
37. Alphey M.S., Gabrielsen M., Micossi E., et al. Tryparedoxins from Crithidia fasciculata and Trypanosoma brucei. J Biol Chem 278 (2003) 25919-25925
38. Thompson L., Denicola A., and Radi R. The trypanothione-thiol system in Trypanosoma cruzi as a key antioxidant mechanism against peroxynitrite-mediated cytotoxicity. Arch Biochem Biophys 412 (2003) 55-64
39. Chandrasekar B., Melby P.C., Troyer D.A., and Freeman G.L. Differential regulation of nitric oxide synthase isoforms in experimental acute chagasic cardiomyopathy. Clin Exp Immunol 121 (2000) 112-119
40. Machado F.S., Martins G.A., Aliberti J.C., Mestriner F.L., Cunha F.Q., and Silva J.S. Trypanosoma cruzi-infected cardiomyocytes produce chemochines and cytokines that trigger potent nitric oxide-dependent trypanocydal activity. Circulation 102 (2000) 3003-3008
41. Garg N., Popov V.L., and Papaconstantinou J. Profiling gene transcription reveals a deficiency in mitochondrial oxidative phosphorylation in Trypanosoma cruzi-infected murine hearts: implications in chagasic myocarditis development. Biochim Biophys Acta 1638 (2003) 106-120
42. Ramasawmy R., Cunha-Neto E., Fae K.C., et al. BAT1, a putative anti-inflammatory gene, is associated with chronic Chagas cardiomyopathy. J Infect Dis 193 (2006) 1394-1399
43. Fae K.C., Drigo S.A., Cunha-Neto E., et al. HLA and beta-myosin heavy chain do not influence susceptibility to Chagas disease cardiomyopathy. Microbes Infect 2 (2000) 745-751