Identification of an isomer impurity in piperaquine drug substance

Journal of Chromatography A

Volumn 1135, Issue 2, 2006, Pages 166-169

  Lindegardh N ^a,b   Giorgi, F ^c   Galletti, B ^c   Di Mattia, M ^c   Quaglia, M ^c   Carnevale, D ^c   White, N J ^a,b   Mazzanti, A ^d   Day, N P J ^a,b  

^a MAHIDOL UNIVERSITY   (Thailand)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c Sigma Tau SpA   (Italy)

^d UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Antimalarial; Impurity; Liquid chromatography; MS; NMR; Piperaquine; Positional isomer

Indexed keywords

IMPURITIES; ISOMERS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS (CHEMICAL);

ANTIMALARIAL DRUG; ISOMER IMPURITY; PIPERAQUINE; POSITIONAL ISOMERS;

DRUG PRODUCTS;

ARTEKIN; DIHYDROARTEMISININ DERIVATIVE; PIPERAQUINE; UNCLASSIFIED DRUG;

ARTICLE; DRUG IDENTIFICATION; DRUG IMPURITY; ISOMER; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; ULTRAVIOLET RADIATION;

ANTIMALARIALS; CHROMATOGRAPHY, LIQUID; ISOMERISM; MAGNETIC RESONANCE SPECTROSCOPY; QUINOLINES; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 33750611489     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2006.09.066     Document Type: Article

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