Etanercept reduces late endotoxin-induced pulmonary hypertension in the pig

Journal of Interferon and Cytokine Research

Volumn 26, Issue 9, 2006, Pages 661-667

  Mutschler, D ^a   Wikstrom G ^a   Lind, L ^a   Larsson, A ^a   Lagrange, A ^a   Eriksson, Mats ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN; ETANERCEPT; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLOR ULTRASOUND FLOWMETRY; CONTINUOUS INFUSION; CONTROLLED STUDY; ENDOTOXEMIA; FEMALE; HEMODYNAMIC MONITORING; HEMODYNAMICS; IMMUNOTHERAPY; LUNG ARTERY PRESSURE; LUNG VASCULAR RESISTANCE; MALE; MITRAL VALVE; NONHUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; PULMONARY HYPERTENSION; SHOCK; TOXIN ANALYSIS;

ANIMALS; BLOOD PRESSURE; ECHOCARDIOGRAPHY, DOPPLER; ENDOTOXINS; HUMANS; HYPERTENSION, PULMONARY; IMMUNOGLOBULIN G; IMMUNOSUPPRESSIVE AGENTS; PLACEBOS; PROSPECTIVE STUDIES; RANDOM ALLOCATION; RECEPTORS, TUMOR NECROSIS FACTOR; SWINE; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR RESISTANCE;

SUS SCROFA;

EID: 33750610016     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.2006.26.661     Document Type: Article

References (27)

1. Marks JD, Marks CB, Luce JM, Montgomery AB, Turner J, Metz CA, Murray JF. Plasma tumor necrosis factor in patients with septic shock. Mortality rate, incidence of adult respiratory distress syndrome, and effects of methylprednisolone administration. Am. Rev. Respir. Dis. 1990;141:94-97.
2. Waage A, Brandtzaeg P, Halstensen A, Kierulf P, Espevik T. The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome. J. Exp. Med. 1989;169:333-338.
3. Eriksson M, Lundkvist K, Larsson A, Nelson D, Saldeen T, Drott P, Eriksson Ö. Vitamin A exerts potential therapeutic effects in the endotoxaemic pigs. Acta Anaesthesiol. Scand. 1997;41:824-829.
4. Eriksson M, Larsson A, Lundkvist K, Lööf L. Endotoxaemic liver injury in a porcine model-Relation to tumor necrosis factor alfa release and survival. Scand. J. Infect. Dis. 1998;30:169-172.
5. Modig J. Adult respiratory distress syndrome. Comp. Pathol Bull 1989;21:2-4.
6. Kettelhut IC, Fiers W, Goldberg AL. The toxic effects of tumor necrosis factor in vivo and their prevention by cyclooxygenase inhibitors. Proc. Natl. Acad. Sci. USA 1987;84:4273-4277.
7. Stevens T, Morris K, McMurtry IF, Zamora M, Tucker A. Pulmonary and systemic vascular responsiveness to TNF-alpha in conscious rats. J. Appl. Physiol 1993;74:1905-1910.
8. Beutler B, Milsark IW, Cerami AC. Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science 1985;229:869-871.
9. Tracey KJ, Fong Y, Hesse DG, Manogue KR, Lee AT, Kuo GC, Lowry SF, Cerami A. Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature 1987;330:662-664.
10. Parker SJ, Brown D, Kenward CE, Watkins PE. Pentoxifylline fails to improve organ dysfunction and survival when used in the resuscitation of a porcine model of haemorrhage and abdominal sepsis. Resuscitation 2000;44:61-69.
11. Cohen J, Carlet J. INTERSEPT: an international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor-alpha in patients with sepsis. International Sepsis Trial Study Group. Crit. Care Med. 1996;24:1431-1440.
12. Abraham E, Anzueto A, Gutierrez G, Tessler S, San Pedro G, Wunderink R, Dal Nogare A, Nasraway S, Berman S, Cooney R, Levy H, Baughman R, Rumbak M, Light RB, Poole L, Allred R, Constant J, Pennington J, Porter S. Double-blind randomised controlled trial of monoclonal antibody to human tumour necrosis factor in treatment of septic shock. NORASEPT II Study Group. Lancet 1998;351:929-933.
13. Panacek EA, Marshall JC, Albertson TE, Johnson DH, Johnson S, MacArthur RD, Miller M, Barchuk WT, Fischkoff S, Kaul M, Teoh L, Van Meter L, Daum L, Lemeshow S, Hicklin G, Doig C. Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab′)2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels. Crit. Care Med. 2004;32:2173-2182.
14. Murray KM, Dahl SL. Recombinant human tumor necrosis factor receptor (p75) Fc fusion protein (TNFR:Fc) in rheumatoid arthritis. Ann. Pharmacother. 1997;31:1335-1338.
15. van der Poll T, Coyle SM, Levi M, Jansen PM, Dentener M, Barbosa K, Buurman WA, Hack CE, ten Gate JW, Agosti JM, Lowry SF. Effect of a recombinant dimeric tumor necrosis factor receptor on inflammatory responses to intravenous endotoxin in normal humans. Blood 1997;89:3727-3734.
16. Suffredini AF, Reda D, Banks SM, Tropea M, Agosti JM, Miller R. Effects of recombinant dimeric TNF receptor on human inflammatory responses following intravenous endotoxin administration. J. Immunol. 1995;155:5038-5045.
17. Darien BJ, Fareed J, Centgraf KS, Hart AP, MacWilliams PS, Clayton MK, Wolf H, Kruse Elliott KT. Low molecular weight heparin prevents the pulmonary hemodynamic and pathomorphologic effects of endotoxin in a porcine acute lung injury model. Shock 1998;9:274-281.
18. Reimold AM. TNFalpha as therapeutic target: new drugs, more applications. Curr. Drug Targets Inflamm. Allergy 2002;1:377-392.
19. Tobin AM, Kirby B. TNFalpha inhibitors in the treatment of psoriasis and psoriatic arthritis. BioDrugs 2005;19:47-57.
20. Eriksson M, Lundkvist K, Drott P, Saldeen T, Eriksson Ö. Beneficial effects of pre-treatment with vitamin A on cardiac and respiratory functions in endotoxaemic pigs. Acta Anaesthesiol Scand. 1996;40:538-548.
21. Eriksson M, Modig J, Larsson A, Rollman O, Eriksson O. Retinyl palmitate injections reduce serum levels and effects of endotoxin on systemic haemodynamics and oxygen transport in the pig. Acta Anaesthesiol. Scand. 1998;42:406-413.
22. Santak B, Radermacher P, Iber T, Adler J, Wachter U, Vassilev D, Georgieff M, Vogt J. In vivo quantification of endotoxin-induced nitric oxide production in pigs from Na15NO3-infusion. Br. J. Pharmacol. 1997;122:1605-1610.
23. Clark CA, Harman EM. Hemodynamic monitoring: Pulmonary artery catheters. In: Civetta JM, Taylor RW, Kirby RR, eds. Critical Care. Philadelphia: J B Lippincott Co; 1988;293-302.
24. Wheeler AP, Hardie WD, Bernard GR. The role of cyclooxygenase products in lung injury induced by tumor necrosis factor in sheep. Am. Rev. Respir. Dis. 1992;145:632-639.
25. Kuriyama T, Wagner jr WW. Collateral ventilation may protect against high-altitude pulmonary hypertension. J. Appl. Physiol. 1981;51:1251-1256.
26. Walley KR, Hebert PC, Wakai Y, Wilcox PG, Road JD, Cooper DJ. Decrease in left ventricular contractility after tumor necrosis factor-alpha infusion in dogs. J. Appl. Physiol. 1994;76:1060-1067.
27. Tsang J, Simon M, Stewart K, Qayumi K, Battistini B. Proinflammatory cytokines are not released in the circulation following acute pulmonary thromboembolism in pigs. J. Invest. Surg. 2002; 15:29-35.