Myoseverin is a potential angiogenesis inhibitor by inhibiting endothelial cell function and endothelial progenitor cell differentiation

DNA and Cell Biology

Volumn 25, Issue 9, 2006, Pages 514-522

  Park, Hyo Eun ^a   Baek, Sang Hong ^a   Min, Jaeki ^b   Chang, Young Tae ^b   Kang, Dong Ku ^c   Chang, Soo Ik ^c   Joe, Young Ae ^a  

^a The Catholic University of Korea   (South Korea)

^b NEW YORK UNIVERSITY   (United States)

^c Chungbuk National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; CD31 ANTIGEN; CELL PROTEIN; COLCHICINE; LOW DENSITY LIPOPROTEIN; MATRIGEL; MYOSEVERIN; NOCODAZOLE; PACLITAXEL; PURINE; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; VINBLASTINE; VON WILLEBRAND FACTOR; ACETYL LOW DENSITY LIPOPROTEIN; ACETYL-LDL; PURINE DERIVATIVE;

ADHERENT CELL; ANGIOGENESIS; ARTICLE; CELL COUNT; CELL CULTURE; CELL DIFFERENTIATION; CELL FUNCTION; CELL GROWTH; CELL LINE; CELL MIGRATION; CELL PROLIFERATION; CHORIOALLANTOIS; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; DOSE RESPONSE; ENDOTHELIUM CELL; EX VIVO STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROTUBULE; MONONUCLEAR CELL; MYOBLAST; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; STEM CELL; UMBILICAL CORD BLOOD; UMBILICAL VEIN; ANIMAL; CELL ADHESION; CELL MOTION; CHICK EMBRYO; CYTOLOGY; DRUG EFFECT; FETUS BLOOD; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); NEWBORN;

ANGIOGENESIS INHIBITORS; ANIMALS; CELL ADHESION; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CHICK EMBRYO; ENDOTHELIAL CELLS; FETAL BLOOD; HUMANS; INFANT, NEWBORN; LIPOPROTEINS, LDL; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; PURINES; STEM CELLS;

EID: 33750605754     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.2006.25.514     Document Type: Article

References (36)

1. ASAHARA, T., MUROHARA, T., SULLIVAN, A., SILVER, M., VAN DER ZEE, R., LI, T., WITZENBICHLER, B., SCHATTEMAN, G., and ISNER, J.M. (1997). Isolation of putative progenitor endothelial cells for angiogenesis. Science 275, 964-967.
2. ASAHARA, T., MASUDA, H., TAKAHASHI, T., KALKA, C., PASTORE, C., SILVER, M., KEARNE, M., MAGNER, M., and ISNER, J.M. (1999a). Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ. Res. 85, 221-228.
3. ASAHARA, T., TAKAHASHI, T., MASUDA, H., KALKA, C., CHEN, D., IWAGURO, H., INAI, Y., SILVER, M., and ISNER, J.M. (1999b). VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO. J. 18, 3964-3972.
4. ASHTON, A.W., YOKOTA, R., JOHN, G., ZHAO, S., SUADICANI, S.O., SPRAY, D.C., and WARE, J.A. (1999). Inhibition of endothelial cell migration, intercellular communication, and vascular tube formation by thromboxane A(2). J. Biol. Chem. 274, 35562-35570.
5. ASSMUS, B., SCHACHINGER, V., TEUPE, C., BRITTEN, M., LEHMANN, R., DOBERT, N., GRUNWALD, F., AICHER, A., URBICH, C., MARTIN, H., et al. (2002). Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction. Circulation 106, 3009-3017.
6. BELOTTI, D., VERGANI, V., DRUDIS, T., BORSOTTI, P., PITELLI, M.R., VIALE, G., GIAVAZZI, R., and TARABOLETTI, G. (1996). The microtubule-affecting drug paclitaxel has antiangiogenic activity. Clin. Cancer Res. 2, 1843-1849.
7. BUSSOLINO, F., MANTOVANI, A., and PERSICO, G. (1997). Molecular mechanisms of blood vessel formation. Trends. Biochem. Sci. 22, 251-256.
8. CRONSTEIN, B.N., MOLAD, Y., REIBMAN, J., BALAKHANE, E., LEVIN, R.I., and WEISSMANN, G. (1995). Colchicine alters the quantitative and qualitative display, of selectins on endothelial cells and neutrophils. J. Clin. Invest. 96, 994-1002.
9. DARK, G.G., HILL, S.A., PRISE, V.E., TOZER, G.M., PETTIT, G.R., and CHAPLIN, D.J. (1997). Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature. Cancer Res. 57, 1829-1834.
10. ESCUIN, D., KLINE, E.R., and GIANNAKAKOU, P. (2005). Both microtubule-stabilizing and microtubule-destabilizing drugs inhibit hypoxia-inducible factor-lalpha accumulation and activity by disrupting microtubule function. Cancer Res. 65, 9021-9028.
11. FOLKMAN, J. (1995a). Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1, 27-31.
12. FOLKMAN, J. (1995b). Seminars in medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis. N. Engl. J. Med. 333, 1757-1763.
13. HAMM-ALVAREZ, S.F., ALAYOF, B.E., HIMMEL, H.M., KIM, P.Y., CREWS, A.L., STRAUSS, H.C., and SHEETZ, M.P. (1994). Coordinate depression of bradykinin receptor recycling and microtubule-dependent transport by taxol. Proc. Natl. Acad. Sci. USA 91, 7812-7816.
14. HOTCHKISS, K.A., ASHTON, A.W., MAHMOOD, R., RUSSELL, R.G., SPARANO, J.A., and SCHWARTZ, E.L. (2002). Inhibition of endothelial cell function in vitro and angiogenesis in vivo by docetaxel (Taxotere): Association with impaired repositioning of the microtubule organizing center. Mol. Cancer. Ther. 1, 1191-1200.
15. HRISTOV, M., ERL, W., LINDER, S., and WEBER, P.C. (2003). Endothelial progenitor cells: Isolation and characterization. Trends. Cardiovasc. Med. 13, 201-206.
16. HUR, J., YOON, C.H., KIM, H.S., CHOI, J.H., KANG, H.J., HWANG, K.K., OH, B.H., LEE, M.M., and PARK, Y.B. (2004). Characterization of two types of endothelial progenitor cells and their different contributions to neovasculogenesis. Arterioscler. Thromb. Vasc. Biol. 24, 288-293.
17. JAFFE, E.A., NACHMAN, R.L., BECKER, C.G., and MINICK, C.R. (1973). Culture of human endothelial cells derived from umbilical veins. Identification by morphological and immunologic criteria. J. Clin. Invest. 52, 2745-2756.
18. JOE, Y.A., BACK, S.H., PARK, H.E., LEE, Y.H., KWON, H.K., KIM, Y.J., LEE, S.Y., SEONG, K.B., CHAE, J.S., KIM, J.H., et al. (2002). In vitro differentiation of endothelial precursor cells derived from umbilical cord blood. Kor. Circ. J. 32, 646-654.
19. KALKA, C., MASUDA, H., TAKAHASHI, T., KALKA-MOLL, W.M., SILVER, M., KEARNEY, M., LI, T., ISNER, J.M., and ASAHARA, T. (2000). Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. Proc. Natl. Acad. Sci. USA 97, 3422-3427.
20. KANTHOU, C., and TOZER, G.M. (2002). The tumor vascular targeting agent combretastatin A-4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells. Blood 99, 2060-2069.
21. KERBEL, R., and FOLKMAN, J. (2002). Clinical translation of angiogenesis inhibitors. Nat. Rev. Cancer 2, 727-739.
22. KLAUBER, N., PARANGI, S., FLYNN, E., HAMEL, E., and D'AMATO, R.J. (1997). Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol. Cancer Res. 57, 81-86.
23. LIAO, G., NAGASAKI, T., and GUNDERSEN, G.G. (1995). Low concentrations of nocodazole interfere with fibroblast locomotion without significantly affecting microtubule level: Implications for the role of dynamic microtubules in cell locomotion. J. Cell Sci. 108(Pt. 11), 3473-3483.
24. MABJEESH, N.J., ESCUIN, D., LAVALLEE, T.M., PRIBLUDA, V.S., SWARTZ, G.M., JOHNSON, M.S., WILLARD, M.T., ZHONG, H., SIMONS, J.W., and GIANNAKAKOU, P. (2003). 2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF. Cancer Cell 3, 363-375.
25. MUROHARA, T., IKEDA, H., DUAN, J., SHINTANI, S., SASAKI, K., EGUCHI, H., ONITSUKA, I., MATSUI, K., and IMAISUMI, T. (2000). Transplanted cord blood-derived endothelial progenitor cells augment postnatal neovascularization. J. Clin. Invest. 105, 1527-1536.
26. NGUYEN, M., and FOLKMAN, J. (1994). Quantitation of angiogenesis and antiangiogenesis in the chick embryo chorioallantoic membrane. Microvasc. Res. 47, 31-40.
27. PEREZ, O.D., CHANG, Y.T., ROSANIA, G., SUTHERLIN, D., and SCHULTZ, P.G. (2002). Inhibition and reversal of myogenic differentiation by purine-based microtubule assembly inhibitors. Chem. Biol. 9, 475-483.
28. PETTIT, G.R., SINGH, S.B., HAMEL, E., LIN, C.M., ALBERTS, D.S., and GARCIA-KENDALL, D. (1989). Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4. Expertentia 45, 209-211.
29. RAFII, S. (2000). Circulating endothelial precursors: Mystery, reality, and promise. J. Clin. Invest. 105, 17-19.
30. REHMAN, J., LI, J., ORSCHELL, C.M., and MARCH, K.L. (2003). Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors. Circulation 107, 1164-1169.
31. ROSANIA, G.R., CHANG, Y.T., PEREZ, O., SUTHERLIN, D., DONG, H., LOCKHART, D.J., and SCHULTZ, P.G. (2000). Myoseverin, a microtubule-binding molecule with novel cellular effects. Nat. Biotechnol. 18, 304-308.
32. SELDON, S.C., RABINOVITCH, P.S., and SCHWARTZ, S.M. (1981). Effects of cytoskeletal disrupting agents on replication of bovine endothelium. J. Cell. Physiol. 108, 195-211.
33. TAKAHASHI, T., KALKA, C., MASUDA, H., CHEN, D., SILVER, M., KEARNEY, M., MAGNER, M., ISNER, J.M., and ASAHARA, T. (1999). Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization. Nat. Med. 5, 434-438.
34. TOZER, G.M., PRISE, V.E., WILSON, J., LOCKE, R.J., VOJNOVIC, B., STRATFORD, M.R., DENNIS, M.F., and CHAPLIN, D.J. (1999). Combretastatin A-4 phosphate as a tumor vascular-targeting agent: Early effects in tumors and normal tissues. Cancer Res. 59, 1626-1634.
35. UEDA, M., GRAF, R., MACWILLIAMS, H.K., SCHLIWA, M., and EUTENEUER, U. (1997). Centrosome positioning and directionality of cell movements. Proc. Natl. Acad. Sci. USA 94, 9674-9678.
36. VOYTA, J.C., VIA, D.P., BUTTERFIELD, C.E., and ZETTER, B.R. (1984). Identification and isolation of endothelial cells based on their increased uptake of acetylated-low density lipoprotein. J. Cell. Biol. 99, 2034-2040.