Identification and localization of adrenomedullin-storing cardiac mast cells

International Journal of Molecular Medicine

Volumn 17, Issue 5, 2006, Pages 709-713

  Belloni, Anna S ^a   Petrelli, Lucia ^a   Guidolin, Diego ^a   De Toni, Renzo ^a   Bova, Sergio ^a   Spinazzi, Raffaella ^a   Gerosa, Gino ^a   Rossi, Gian Paolo ^a   Nussdorfer, Gastone G ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Adrenomedullin; Heart; Human; Mast cells; Rat

Indexed keywords

4 METHOXY N METHYLPHENETHYLAMINE; ADRENOMEDULLIN; PEPTIDE;

ANIMAL; ARTICLE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; ELECTRON MICROSCOPY; HEART MUSCLE; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; MAST CELL; RAT; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

ADRENOMEDULLIN; ANIMALS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MAST CELLS; MICROSCOPY, ELECTRON; MYOCARDIUM; P-METHOXY-N-METHYLPHENETHYLAMINE; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33750604183     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.17.5.709     Document Type: Article

References (29)

1. Lopez J and Martinez A: Cell and molecular biology of the multifunctional peptide adrenomedullin. Int Rev Cytol 221: 1-92, 2002. (Pubitemid 35429860)
2. Eto T, Kato J and Kitamura K: Regulation of production and secretion of adrenomedullin in the cardiovascular system. Regul Pept 112: 61-70, 2003.
3. Belloni AS, Guidolin D, Ceretta S, Bova S and Nussdorfer GG: Acute effects of endothelins on endogenous adrenomedullin system in the rat heart: immunocytochemical and autoradiographic studies. Int J Mol Med 13: 669-674, 2004.
4. Belloni AS, Guidolin D, Ceretta S, Bova S and Nussdorfer GG: Acute effects of ischemia on adrenomedullin immunoreactivity in the rat heart: an immunocytochemical study. Int J Mol Med 14: 71-73, 2004.
5. Welsch U, Unterberger P, Höfter E, Cuttitta F and Martinez A: Adrenomedullin in mammalian and human skin glands including the mammary gland. Acta Histochem 104: 65-72, 2002.
6. Martinez A, Saldise L, Ramirez MJ, Belzunegui S, Zudaire E, Luquin MR and Cuttitta F: Adrenomedullin expression and function in the rat carotic body. J Endocrinol 176: 95-102, 2003.
7. Belloni AS, Guidolin D, Salmaso R, Bova S, Rossi GP and Nussdorfer GG: Adrenomedullin, ANP and BNP are colocalized in a subset of endocrine cells in the rat heart. Int J Mol Med 15: 567-571, 2005.
8. Brower GL, Chancey AL, Thanigaraj S, Matsubara BB and Janicki JS: Cause and effect relationship between myocardial mast cell number and matrix metalloproteinase activity. Am J Physiol 283: H518-H525, 2002.
9. De Angeli S, Di Liddo R, Buoro S, Toniolo L, Conconi MT, Belloni AS, Parnigotto PP and Nussdorfer GG: New immortalized human stromal cell lines enhancing in vitro expansion of cord blood hematopoietic stem cells. Int J Mol Med 13: 363-371, 2004.
10. Koibuchi Y, Ichikawa A, Nakagawa M and Kenkichi T: Histamine release induced from mast cells by active components of compound 48/80. Eur J Pharmacol 115: 163-170, 1985. (Pubitemid 16222890)
11. Crivellato E, Beltrami CA, Mallardi F and Ribatti D: The mast cell: an active participant or an innocent bystander? Histol Histopathol 19: 259-270, 2004.
12. Hultner L and Ehrenreich H: Mast cells and endothelin-1: a life-saving biological liason? Trends Immunol 26: 235-238, 2005.
13. Kempuraj D, Papadopoulou NG, Lytinas M, Huang M, Kandere-Grzybowska K, Madhappan B, Boucher WS, Christodoulou S, Athanassiou A and Theoharides TC: Corticotropin- releasing hormone and its structurally related urocortin are synthesized and secreted by human mast cells. Endocrinology 145: 43-48, 2004.
14. Silver RB, Reid AC, Mackins CJ, Askwith T, Schaefer U, Herzlinger D and Levi R: Mast cells: a unique source of renin. Proc Natl Acad Sci USA 101: 13607-13612, 2004.
15. Yoshida M, Yoshida H, Kitaichi K, Hiramatsu K, Kitamura T, Ito Y, Kume H, Yamaki K, Suzuki R, Shibata E, Hasegawa T and Takagi K: Adrenomedullin and proadrenomedullin N-terminal 20 peptide induce histamine release from rat peritoneal mast cells. Regul Pept 101: 163-168, 2001.
16. Hamid SA and Baxter GF: Adrenomedullin: regulator of systemic and cardiac homeostasis in acute myocardial infarction. Pharmacol Ther 105: 95-112, 2005.
17. Terata K, Miura H, Liu Y, Loberiza F and Gutterman DD: Human coronary arteriolar dilation to adrenomedullin: role of nitric oxide and K+ channels. Am J Physiol 279: H2620-H2626, 2000.
18. De Matteo R and May CN: Direct coronary vasodilator action of adrenomedullin is mediated by nitric oxide. Br J Pharmacol 140: 1414-1420, 2003.
19. Niu P, Shindo T, Iwata H, Iimuro S, Takeda N, Zhang Y, Ebihara A, Suematsu Y, Kangawa K, Hirata Y and Nagai R: Protective effects of endogenous adrenomedullin on cardiac hypertrophy, fibrosis, and renal damage. Circulation 109: 1789-1794, 2004.
20. Nishikimi T, Tadokoro K, Akimoto K, Mori Y, Ishikawa Y, Ishimura K, Horio T, Kangawa K and Matsuoka M: Response of adrenomedullin system to cytokine in cardiac fibroblasts. Role of adrenomedullin as an antifibrotic factor. Cardiovasc Res 66: 104-113, 2005.
21. Tsuruda T, Kato J, Hatakeyama K, Masuyama H, Cao YN, Inamura T, Kitamura K, Asada Y and Eto T: Antifibrotic effect of adrenomedullin on coronary adventitia in angiotensin II-induced hypertensive rats. Cardiovasc Res 65: 921-929, 2005.
22. Nagaya N, Mori M, Murakami S, Kangawa K and Kitamura S: Adrenomedullin: angiogenesis and gene therapy. Am J Physiol 288: R1432-R1437, 2005.
23. Ribatti D, Nico B, Spinazzi R, Vacca A and Nussdorfer GG: The role of adrenomedullin in angiogenesis. Peptides 26: 1670-1675, 2005.
24. Ginsburg R, Bristow MR and Davis K: Receptor mechanisms in the human epicardial coronary artery. Heterogeneous pharmacological response to histamine and carbacol. Circ Res 55: 416-421, 1984.
25. Murray DB, Gardner JD, Brower GL and Janicki JS: Endothelin-1 mediates cardiac mast cell degranulation, matrix metalloproteinase activation, and myocardial remodeling in rats. Am J Physiol 287: H2295-H2299, 2004.
26. Upadhya B, Kontos JL, Ardeshirpour F, Pye J, Boucher WS, Theoharides TC, Dehmer GJ and Deliargyris EN: Relation of serum levels of mast cell tryptase to left ventricular systolic function, left ventricular volume or congestive heart failure. J Card Fail 10: 31-35, 2004.
27. Norby K: Mast cells and angiotensins. APMIS 110: 355-371, 2002.
28. Lappalainen H, Laine P, Pentikainen MO, Sajantila A and Kovanen PT: Mast cells in neovascularized human coronary plaques store and secrete basic fibroblast growth factor, a potent angiogenic mediator. Arterioscler Thromb Vasc Biol 24: 1880-1885, 2004.
29. Matsumori A: Role of hepatocyte growth factor and mast cells in thrombosis and angiogenesis. Cardiovasc Drugs Ther 18: 321-326, 2004.