New bioorganic reagents: Evolved cyclohexanone monooxygenase - Why is it more selective?

Journal of Organic Chemistry

Volumn 71, Issue 22, 2006, Pages 8424-8430

  Kayser, Margaret M ^a   Clouthier, Christopher M ^a  

^a UNIVERSITY OF NEW BRUNSWICK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSTS; COMPOSITION; ENZYMES; MUTAGENS; ORGANIC COMPOUNDS; OXIDATION;

4-HYDROXYCYCLOHEXANONES; BIOORGANIC REAGENTS; BIOTRANSFORMATIONS; CYCLOHEXANONE MONOOXYGENASES;

BIOCHEMISTRY;

CYCLOHEXANONE DERIVATIVE; CYCLOHEXANONE MONOOXYGENASE; MUTANT PROTEIN; PHENYLALANINE; REAGENT; SERINE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ARTICLE; BAEYER VILLIGER REACTION; BIOTRANSFORMATION; CATALYST; ENANTIOSELECTIVITY; ENZYME MECHANISM; ENZYME SUBSTRATE; REACTION ANALYSIS; WILD TYPE;

AMINO ACID SUBSTITUTION; BINDING SITES; CATALYSIS; CYCLOHEXANONES; DIRECTED MOLECULAR EVOLUTION; MODELS, CHEMICAL; MOLECULAR STRUCTURE; MUTATION; OXIDATION-REDUCTION; OXYGENASES; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 33750594766     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo061349t     Document Type: Article

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