Efficacy and safety of Itraconazole injections and capsules in deep mycosis uncontrolled multicenter open-label trial

Japanese Journal of Chemotherapy

Volumn 54, Issue , 2006, Pages 32-47

  Kohno, Shigeru ^a   Yamaguchi, Hideyo ^b   Mori, Takeshi ^c   Hirai, Hisamaru ^d   Oritsu, Masaru ^e   Niki, Yoshihito ^f   Yoshida, Minoru ^g   Maesaki, Shigefumi ^h   Hiraoka, Akira ⁱ   Kurashima, Atsuyuki ^j  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b TEIKYO UNIVERSITY   (Japan)

^c JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF TOKYO HOSPITAL   (Japan)

^e JAPANESE RED CROSS MEDICAL CENTER   (Japan)

^f Department of Respiratory Medicine   (Japan)

^g TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^h SAITAMA MEDICAL UNIVERSITY HOSPITAL   (Japan)

ⁱ OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

^j NATIONAL HOSPITAL ORGANIZATION   (Japan)

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Author keywords

aspergillosis; candidiasis; cryptococcosis; injection; itraconazole

Indexed keywords

ITRACONAZOLE;

ABDOMINAL DISCOMFORT; ABDOMINAL DISTENSION; ADOLESCENT; ADULT; AGED; ANEMIA; ANOREXIA; ANXIETY DISORDER; AREA UNDER THE CURVE; ARTICLE; ASPERGILLOSIS; ASPERGILLUS; ASTHENIA; AUTOMUTILATION; BACKACHE; BLOOD TOXICITY; BODY WEIGHT DISORDER; BRADYCARDIA; CANDIDA; CANDIDIASIS; CHILL; CONGESTIVE HEART FAILURE; CONSTIPATION; CONTROLLED STUDY; COUGHING; CRYPTOCOCCOSIS; CRYPTOCOCCUS; DEPRESSION; DIARRHEA; DISEASE SEVERITY; DIZZINESS; DOSE RESPONSE; DROWSINESS; DRUG BLOOD LEVEL; DRUG CAPSULE; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG ERUPTION; DRUG INDUCED HEADACHE; DRUG SAFETY; DRY SKIN; DYSESTHESIA; DYSKINESIA; DYSPHONIA; DYSPNEA; ECZEMA; EPIGASTRIC PAIN; ERYTHEMA; FEMALE; FEVER; FLATULENCE; FUNGAL STRAIN; GASTRITIS; GASTRODUODENAL ULCER; GASTROINTESTINAL SYMPTOM; GASTROINTESTINAL TOXICITY; GIARDIASIS; GLUCOSURIA; HEART FAILURE; HEART PALPITATION; HEART RIGHT BUNDLE BRANCH BLOCK; HEMATURIA; HUMAN; HYPERKALEMIA; HYPERTENSION; HYPERTRIGLYCERIDEMIA; HYPOCHOLESTEROLEMIA; HYPOKALEMIA; HYPONATREMIA; INDIGESTION; INJECTION SITE PAIN; INJECTION SITE REACTION; INJECTION SITE SWELLING; LEUKOPENIA; LIVER INJURY; LIVER TOXICITY; LOOSE FECES; LUNG HEMORRHAGE; MAINTENANCE DRUG DOSE; MAJOR CLINICAL STUDY; MALAISE; MALE; MAXIMUM PERMISSIBLE DOSE; MUSCLE RIGIDITY; MYCOSIS; NAUSEA; NEPHROTOXICITY; NONHUMAN; PERIPHERAL SWELLING; PNEUMONIA; POLLAKISURIA; PROTEINURIA; PRURITUS; RETINA HEMORRHAGE; SENSORY DYSFUNCTION; SIDE EFFECT; SKIN SWELLING; SYSTEMIC DISEASE; TACHYCARDIA; TASTE DISORDER; THROMBOCYTOPENIA; TREATMENT DURATION; TREMOR; URINE VOLUME; VALVULAR HEART DISEASE; VASCULAR DISEASE; VOMITING; WEIGHT GAIN; XEROSTOMIA;

EID: 33750581303     PISSN: 13407007     EISSN: None     Source Type: Journal    
DOI: 10.11250/chemotherapy1995.54.Supplement1_32     Document Type: Article

References (4)

1. Caillot D, Bassaris H, McGear A, Arthut C, Prentice H G, Seifert W, et. al. : Intravenous itraconazole followed by oral itraconazole in the treatment of invasive pulmonary aspergillosis in patients with hematologic malignancies, chronic granulomatous disease, or AlDs. CID 2001; 33 : 83-90
2. Boogaerts M, Winston D J, Bow E J, Garber G, Reboli A C, Schwarer A P, et. al. : Intravenous and oral itraconazole versus intravenous amphotericin B deoxy-cholate as empirical antifungal therapy for persistent fever in neutropenic patients with cancer who are receiving broad-specturm antibacterial therapy. Ann Intem Med 2001; 135 : 412-22
3. Stevens D A, Kan V L, Judson M A, Morrison V A, Dummer S, Denning D W, et. al. : Practice Guidelines for Disease Caused by Aspergillus. CID 2000; 38 : 696-709
4. Pappas P G, Rex J H, Sobel J D, Fillet S G, Dismukes W E, Walsh T J, et. al. : Guidelines for treatment of candidiasis. CID 2004; 38 : 161-89