Stability of nevirapine suspension in prefilled oral syringes used for reduction of mother-to-child HIV transmission

Journal of Acquired Immune Deficiency Syndromes

Volumn 43, Issue 3, 2006, Pages 373-375

  Rexroad, Vivian E ^a   Parsons, Teresa L ^b   Hamzeh, Fayez M ^b,c   Li, Xianbin ^d   Dreyfuss, Michele L ^d   Stamper, Paul D ^d   Gray, Ronald H ^d  

^a JOHNS HOPKINS HOSPITAL   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HOFFMANN LA ROCHE INC   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Africa; Mother to child HIV transmission (MTCT); Nevirapine; Nevirapine stability in oral syringes; Vertical HIV transmission

Indexed keywords

NEVIRAPINE;

ARTICLE; CONCENTRATION RESPONSE; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM; DRUG PACKAGING; DRUG STABILITY; DRUG STORAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INCUBATION TIME; INFECTION PREVENTION; INFECTION RISK; PREGNANT WOMAN; PRIORITY JOURNAL; RISK REDUCTION; SUSPENSION; SYRINGE; TABLET; VERTICAL TRANSMISSION;

ADMINISTRATION, ORAL; ANTI-HIV AGENTS; DISEASE TRANSMISSION, VERTICAL; DRUG PACKAGING; DRUG STABILITY; DRUG STORAGE; FEMALE; HIV INFECTIONS; HUMANS; INFANT; NEVIRAPINE; PERINATAL CARE; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; SELF ADMINISTRATION; SUSPENSIONS; SYRINGES; TEMPERATURE;

EID: 33750574566     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.qai.0000242458.51015.25     Document Type: Article

References (5)

1. Guay LA, Musoke P, Fleming T, et al. Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial. Lancet. 1999;354:795-802.
2. Uganda Bureau of Statistics and ORC Macro. Uganda Demographic and Health Survey 2000-2001. Calverton, MD: UBOS, ORC Macro; 2001.
3. Kagaayi J, Dreyfuss ML, Kigozi G, et al. Maternal self-medication and provision of nevirapine to infants by women in Rakai, Uganda. J Acquir Immune Defic Syndr. 2005;39:121-124.
4. Viramune® [prescribing information]. Boehringer Ingelheim Pharmaceuticals, Inc.; January 11, 2005.
5. Pav JW, Rowland LS, Korpalski DJ. HPLC-UV method for the quantitation of nevirapine in biological matrices following solid phase extraction. J Pharm Biomed Anal. 1999;20:91-98.