Osteonecrosis of the jaw: What do bisphosphonates do?

Expert Opinion on Drug Safety

Volumn 5, Issue 6, 2006, Pages 743-745

  Aspenberg, Per ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Bisphosphonate; Osteoclast; Osteonecrosis

Indexed keywords

ANTINEOPLASTIC AGENT; BISPHOSPHONIC ACID DERIVATIVE; CORTISONE;

ACTINOMYCES; BACTERIAL COLONIZATION; BONE NECROSIS; BONE REMODELING; CANCER; CELL DEATH; DRUG INDUCED DISEASE; DRUG POTENTIATION; EDITORIAL; HUMAN; INFECTION RESISTANCE; INFECTION SENSITIVITY; JAW DISEASE; LONG TERM CARE; OSSIFICATION; OSTEOCYTE; OSTEOLYSIS; PAGET BONE DISEASE; PATHOGENESIS;

DIPHOSPHONATES; HUMANS; JAW; JAW DISEASES; OSTEONECROSIS;

EID: 33750558328     PISSN: 14740338     EISSN: None     Source Type: Journal    
DOI: 10.1517/14740338.5.6.743     Document Type: Editorial

References (4)

1. KOLATA G: Drugs for bones newly linked to jaw disease. New York Times (2006) 2 June.
2. RUGGIERO SL, MEHROTRA B, ROSENBERG TJ, ENGROFF SL: Osteonecrosis of the jaws associated with the use of bisphosphonates: a review of 63 cases. J. Oral Maxillofac. Surg. (2004) 62(5):527-534.
3. MARX R E, SAWATARI Y, FORTIN M, BROUMAND V: Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment. J. Oral Maxillofac. Surg. (2005) 63(11):1567-1575.
4. HANSEN T, KUNKEL M, WEBER A, JAMES KIRKPATRICK C: Osteonecrosis of the jaws in patients treated with bisphosphonates - histomorphologic analysis in comparison with infected osteoradionecrosis. J. Oral Pathol. Med. (2006) 35(3):155-160.