Dietary accumulation of hexabromocyclododecane diastereoisomers in juvenile rainbow trout (Oncorhynchus mykiss) I: Bioaccumulation parameters and evidence of bioisomerization

Environmental Toxicology and Chemistry

Volumn 25, Issue 7, 2006, Pages 1757-1761

  Law, Kerri ^a,b   Palace, Vince P ^a,b   Halldorson, Thor ^a   Danell, Robert ^a   Wautier, Kerry ^a   Evans, Bob ^a   Alaee, Mehran ^c   Marvin, Chris ^c   Tomy, Gregg T ^a,b  

^a FRESHWATER INSTITUTE   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

^c ENVIRONMENT CANADA   (Canada)

Author keywords

Bioaccumulation parameters; Bioisomerization; Dietary accumulation; Hexabromocyclododecane

Indexed keywords

BIODIVERSITY; CONCENTRATION (PROCESS); ISOMERIZATION; PARAFFINS; REACTION KINETICS;

BIOACCUMULATION; BIOACCUMULATION PARAMETERS; BIOISOMERIZATION; DEPURATION KINETICS; DIASTEREOISOMERS; HEXABROMOCYCLODODECANE;

ISOMERS;

HEXABROMOCYCLODODECANE;

BIOACCUMULATION; DIET; FISH; FOOD INTAKE; JUVENILE; ORGANIC COMPOUND;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIASTEREOISOMER; DIET; FISH; FOOD; IN VIVO STUDY; ISOMERIZATION; KINETICS; NONHUMAN; PRIORITY JOURNAL; RAINBOW TROUT;

AGING; ANIMALS; DIET; HYDROCARBONS, BROMINATED; STEREOISOMERISM; TROUT;

ONCORHYNCHUS MYKISS;

EID: 33750548266     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/05-445R.1     Document Type: Article

References (16)

1. Arias PA. 2001. Brominated flame retardants-An overview. Proceedings, 2nd International Workshop on Brominated Flame Retardants, Stockholm, Sweden, May 14-16, pp 17-19.
2. Heeb NV, Schweizer WB, Kohler M, Gerecke AC. 2004. 1,2,5,6,9,10- hexabromocyclododecane-A class of compounds with a complex stereochemistry. Proceedings, 3rd International Workshop on Brominated Flame Retardants, ON, Canada, June 6-9, pp 337-339.
3. De Wit C. 2002. An overview of brominated flame retardants in the environment. Chemosphere 46:583-624.
4. Ronisz D, Finne EF, Karlsson H, Förlin L. 2004. Effects of the brominated flame retardants hexabromocyclododecane (HBCDD), and tetrabromobisphenol A (TBBPA), on hepatic enzymes and other biomarkers in juvenile rainbow trout and feral eelpout. Aquat Toxicol 69:229-245.
5. Helleday T, Tuominen K-L, Bergman Å, Jenssen D. 1999. Brominated flame retardants induce intragenic recombination in mammalian cells. Mutat Res 439:137-147.
6. Sellström U, Kierkegaard A, De Wit C, Jansson B. 1998. Polybrominated diphenyl ethers and hexabromocyclododecane in sediment and fish from a Swedish river. Environ Toxicol Chem 17:1065-1072.
7. Barontini F, Cozzani V, Cuzzola A, Petarca L. 2001. Investigation of hexabromocyclododecane thermal degradation pathways by gas chromatography/mass spectrometry. Rapid Commun Mass Spectrom 15:690-698.
8. Tomy GT, Budakowski WR, Halldorson THJ, Whittle DM, Keir MJ, MacInnis G, Alaee M. 2004. Biomagnification of α- and α-hexabromocyclododecane (HBCD) isomers in a Lake Ontario food web. Environ Sci Technol 38:2298-2303.
9. Morris S, Allchin CR, Zegers BN, Haftka JJH, Boon JP, Belpaire C, Leonards PEG, van Leeuwen SPJ, De Boer J. 2004. Distribution and fate of HBCD and TBBPA brominated flame retardants in North Sea estuaries and aquatic food webs. Environ Sci Technol 38:5497-5504.
10. Zegers BN, Mets A, van Bommel R, Minkenberg C, Hamers T, Kamstra JH, Pierce GJ, Boon JP. 2005. Levels of hexabromocyclododecane in harbor porpoises and common dolphins from western European seas, with evidence for stereoisomer-specific biotransformation by cytochrome P450. Environ Sci Technol 39:2095-2100.
11. Benezet HJ, Matsumuar F. 1973. Isomerization of γ-BHC to α-BHC in the environment. Nature 243:480-481.
12. Tomy GT, Palace VP, Halldorson THJ, Braekevelt E, Danell RW, Wautier K, Evans B, Brinkworth L, Fisk AT. 2004. Bioaccumulation, biotransformation, and biochemical effects of brominated diphenyl ethers (BDEs) in juvenile lake trout (Salvelinus namaycush). Environ Sci Technol 38:1496-1504.
13. Budakowski WR, Tomy GT. 2003. Congener-specific analysis of hexabromocyclododecane by high-performance liquid chromatography/electrospray tandem mass spectrometry. Rapid Commun Mass Spectrom 17:1399-1404.
14. Tomy G, Halldorson T, Danell R, Law K, Arsenault G, Alaee M, MacInnis G, Marvin C. 2005. Refinements to the diastereoisomer specific method for the analysis of hexabromocyclododecane. Rapid Commun Mass Spectrom 19:2818-2826.
15. Stapleton HM, Alaee M, Letcher R, Baker J. 2004. Debromination of the flame retardant decabromodiphenyl ether by juvenile carp (Cyprinus carpio) following dietary exposure. Environ Sci Technol 38:112-119.
16. Dean RB, Dixon WJ. 1951. Simplified statistics for small numbers of observations. Anal Chem 23:636-638.