The kinetic model of the shikimate pathway as a tool to optimize enzyme assays for high-throughput screening

Biotechnology and Bioengineering

Volumn 95, Issue 4, 2006, Pages 560-571

  Noble, Michael ^a,e   Sinha, Yugesh ^a   Kolupaev, Aleksey ^b,c   Demin, Oleg ^b,c   Earnshaw, David ^a   Tobin, Frank ^d   West, Joshua ^d   Martin, John D ^d   Qiu, Chunyan ^d   Liu, Wu Schyong ^d   DeWolf, Walter E ^d   Tew, David ^a   Goryanin, Igor I ^a,f  

^a GLAXOSMITHKLINE   (United Kingdom)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

^c Institute for Systems Biology SPb   (Russian Federation)

^d GLAXOSMITHKLINE   (United States)

^e F HOFFMANN LA ROCHE LTD   (Switzerland)

^f UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; GROWTH KINETICS; MATHEMATICAL MODELS; SCREENING; SPECTROPHOTOMETERS;

FOUR-ENZYME SECTION; SCREENING EFFORT; SHIKIMATE PATHWAY;

BIOASSAY;

SHIKIMIC ACID;

ARTICLE; CHEMICAL MODEL; CHEMICAL REACTION; CONTROLLED STUDY; ENZYME ASSAY; ENZYME KINETICS; HIGH THROUGHPUT SCREENING; NONHUMAN; STREPTOCOCCUS PNEUMONIAE;

STREPTOCOCCUS PNEUMONIAE;

EID: 33750544499     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.20772     Document Type: Article

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