Shelf-life prediction of intravenous busulfan by isothermal calorimetry

Hospital Pharmacist

Volumn 13, Issue 8, 2006, Pages 295-298

  Gaisford, Simon ^a   O'Neill, Michael ^a   Thompson, Lucy ^b,c   Chan, Kai Loke ^c  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b Aseptic Services

^c KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BUSULFAN;

ARTICLE; CALORIMETRY; DRUG DEGRADATION; DRUG STABILITY; DRUG STORAGE; INTRAVENOUS ADMINISTRATION; ISOTHERMAL CALORIMETRY; SHELF LIFE; TEMPERATURE DEPENDENCE;

EID: 33750524027     PISSN: 13527967     EISSN: 13527967     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Peters WP, Henner WD, Grochow LD, Olsen G, Edwards S, Stanbuck H et al. Clinical and pharmacologic effects of high dose single agent busulfan with autologous bone marrow support in the treatment of solid tumors. Cancer Research 1987;47:6402-6.
2. Hassan M, Ehrsson H. Metabolism of 14C-busulfan in isolated perfused rat liver. European Journal of Drug Metabolism and Pharmacokinetics 1987;12:71-6.
3. Andersson BS, Bhagwatwar HP, Chow DS-L. Parenteral busulfan for treatment of malignant disease. US Patent 5,430,057 (1995).
4. Andersson BS, Bhagwatwar HP, Chow DS-L. Parenteral busulfan for treatment of malignant disease. US Patent 5,559,148 (1996).
5. Bhagwatwar HP, Phadungpojna S, Chow DS-L, Andersson BS. Formulation and stability of busulfan for intravenous administration in high dose chemotherapy. Cancer Chemotherapy and Pharmacology 1996;37:401-8.
6. Pierre Fabre Ltd. Busilvex data sheet. In: Association of the British Pharmaceutical Industry. Medicines Compendium 2005. Epsom: Datapharm Communications; 2005.
7. Chow DS-L, Bhagwatwar HP, Phadungpojna S, Andersson BS. Stability-indicating high-performance liquid chromatographic assay of busulfan in aqueous and plasma samples. Journal of Chromatography B;704: 277-88.
8. Gaisford S. Stability assessment of pharmaceuticals and biopharmaceuticals by isothermal calorimetry. Current Pharmaceutical Biotechnology 2005;6: 181-91.
9. O'Neill MAA. Recent developments for the analysis of data obtained from isothermal calorimetry. Current Pharmaceutical Biotechnology 2005;6:05-14.