Antisense knockdown of the rat α7 nicotinic acetylcholine receptor produces spatial memory impairment

Neuroscience Letters

Volumn 410, Issue 1, 2006, Pages 15-19

  Curzon, Peter ^a   Anderson, David J ^a   Nikkel, Arthur L ^a   Fox, Gerard B ^a   Gopalakrishnan, Murali ^a   Decker, Michael W ^a   Bitner, Robert S ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Cortex; Hippocampus; Nicotinic 7; Spatial memory; Water maze

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CYTISINE; METHYLLYCACONITINE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA7; RADIOLIGAND; RECEPTOR SUBUNIT; TRITIUM; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ANALYSIS OF VARIANCE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING ASSAY; BRAIN CORTEX; BRAIN VENTRICLE; CONTROLLED STUDY; HIPPOCAMPUS; LEARNING; MALE; MAZE TEST; MEMORY DISORDER; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; RECEPTOR BINDING; RECEPTOR DENSITY; SPATIAL MEMORY; TASK PERFORMANCE;

ACONITINE; ALKALOIDS; ANIMALS; AZOCINES; BEHAVIOR, ANIMAL; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; HIPPOCAMPUS; MALE; MAZE LEARNING; MEMORY DISORDERS; NICOTINIC ANTAGONISTS; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; PROTEIN BINDING; QUINOLIZINES; RATS; RATS, LONG-EVANS; RECEPTORS, NICOTINIC; SPACE PERCEPTION; TIME FACTORS; TRITIUM;

EID: 33750520359     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2006.09.061     Document Type: Article

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