Recombinant activated factor seven in acute life-threatening bleeding in neonates: Report on three cases and review of literature

Journal of Perinatology

Volumn 26, Issue 11, 2006, Pages 706-713

  Hunseler C ^a   Kribs, A ^a   Eifinger, F ^a   Roth, B ^a  

^a UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; DOBUTAMINE; DOPAMINE; FRESH FROZEN PLASMA; INDOMETACIN; RANITIDINE; RECOMBINANT BLOOD CLOTTING FACTOR 7A; SODIUM CHLORIDE; VITAMIN K GROUP;

AIRWAY OBSTRUCTION; ARTICLE; ARTIFICIAL VENTILATION; BLEEDING; CASE REPORT; CESAREAN SECTION; CHILD DEVELOPMENT; CONVALESCENCE; DISEASE SEVERITY; DRUG EFFICACY; ERYTHROCYTE TRANSFUSION; FEMALE; GASTROINTESTINAL HEMORRHAGE; HEMOSTASIS; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HOSPITAL DISCHARGE; HUMAN; INTERNATIONAL NORMALIZED RATIO; MALE; MEDICAL LITERATURE; NEONATAL HEMORRHAGE; NEONATOLOGY; NEWBORN; NEWBORN HYPOXIA; PERINATAL PERIOD; PLASMA TRANSFUSION; POLYMERASE CHAIN REACTION; POSITIVE END EXPIRATORY PRESSURE; PREMATURITY; RESPIRATORY FAILURE; RESUSCITATION; STOMACH LAVAGE; THROMBOCYTE TRANSFUSION; THROMBOSIS; TREATMENT OUTCOME;

FACTOR VII; FEMALE; HEMORRHAGE; HEMOSTASIS; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; MALE; RECOMBINANT PROTEINS; TREATMENT OUTCOME;

EID: 33750486840     PISSN: 07438346     EISSN: 14765543     Source Type: Journal    
DOI: 10.1038/sj.jp.7211588     Document Type: Article

References (19)

1. Heuer L, Blumenberg D. Recombinant factor VIIa (NovoSevens®). A review of current and possible future indications. Anaesthesist 2002; 51: 388-399.
2. Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN et al. Recombinant activated factor VII for acute intracerebral hemorrhage. New Engl J Med 2005; 352: 777-785.
3. Chuansumrit A, Visanuyothin N, Puapunwattana S, Chaivisuth A, Rasmidat P, Charoenkwan P et al. Outcome of intracranial hemorrhage in infants with congenital factor VII deficiency. J Med Assoc Thai 2002; 85(S4): 1059-1064.
4. Wong WY, Huang WC, Miller R, McGinty K, Whisnat JK. Clinical efficacy and recovery levels of recombinant FVIIa (Novoseven) in the treatment of intracranial haemorrhage in severe neonatal FVII deficiency. Haemophilia 2000; 6: 50-54.
5. Tancabelic J, Haun SE. Management of coagulopathy with recombinant factor VIIa in a neonate with echovirus type 7. Pediatr Blood Cancer 2004; 43: 170-176.
6. Wittenstein B, Ng C, Ravn H, Goldmann A. Recombinant factor VII for severe bleeding during extracorporeal membrane oxygenation following open heart surgery. Pediatr Crit Care Med 2005; 6: 473-476.
7. Velik-Salchner C, Sergi C, Fries D, Moser P, Streif W, Kolbitsch C. Use of recombinant factor VIIa (Novoseven) in combination with other products led to a thrombotic occlusion of the truncus brachiocephalicus in a neonate supported by exracorporal membrane oxygenation. Anesth Analg 2005; 101: 924.
8. Razon Y, Erez E, Vidne B, Birk E, Katz J, Tamari H et al. Recombinant factor VIIa (NovoSevens®) as a hemostatic agent after surgery for congenital heart disease. Pediatric Anesth 2005; 15: 235-240.
9. Girisch M, Rauch R, Carbon R, Habash T, Hofbeck M. Refractory bleeding following major surgery of a giant teratoma in a premature infant: succesful use of recombinant factor VIIa. Eur J Pediatr 2004; 163: 118-119.
10. Millar CG, Stringer MD, Sugarman I, Richards M. The use of recombinant factor VIIa for bleeding in paediatric practice. Haemophilia 2005; 11: 171-174.
11. Veldman A, Fischer D, Voigt B, Beyer PA, Schloösser R, Allendorf A et al. Life-threatening hemorrhage in neonates management with recombinant activated factor VII. Intens Care Med 2002; 28: 1635-1637.
12. Filan PM, Mills JF, Clarnette TD, Ekert H, Ekert P. Spontaneous liver hemorrhage during laparotomy for necrotizing enterocolitis: A potential role for recombinant factor VIIa. J Pediatr 2005; 147: 857-859.
13. Chuansumrit A, Nuntnarumit P, Okascharoen C, Teerakatkul S, Suwansingh S, Supapannachart S. The use of recombinant activated factor VII to control bleeding in a preterm infant undergoing exploratory laparotomy. Pediatrics 2002; 107: 169-170.
14. Olomu N, Kulkarni N, Manco-Johnson M. Treatment of severe pulmonary hemorrhage with activated recombinant factor VII (rFVIIa) in very low birth weight infants. J Perinatol 2002; 22: 672-674.
15. Villar A, Aronis S, Morfini M, Santagostino E, Auerswald G, Thomsen HF et al. Pharmacokinetics of activated recombinant coagulation factor VII (NovoSeven) in children vs adults with haemophilia A. Haemophilia 2004; 10: 352-359.
16. Fontaine MJ, Lazarchick J, Taylor S, Annibale D. Use of recombinant factor VIIa in Infants with severe coagulopathy. J Perinatol 2004; 24: 310-311.
17. Greisen G, Andreasen RB. Recombinant factor VIIa in preterm neonates with prolonged prothrombin time. Blood Coagul Fibrinolysis 2003; 14: 117-120.
18. Maimon M, Bernstein T, Kenet G, Kapelushnik J. Recombinant factor VIIa for treatment of a child with severe factor VII deficiency and coarctation of the aorta. J Pediatr Hematol Oncol 2003; 25: 591.
19. Tokunaga C, Hiramatsu Y, Horigome H, Takahashi-Igari M, Noma M, Sakakibara Y. Palliative open heart surgery in an infant with factor VII deficiency. Ann Thorac Surg 2003; 76: 2093-2094.