Primer: Histopathology of polyomavirus-associated nephropathy in renal allografts

Nature Clinical Practice Nephrology

Volumn 2, Issue 11, 2006, Pages 631-636

  Liptak, Peter ^a   Kemeny, Eva ^b   Ivanyi, Bela ^b  

^a Glasgow School of Pathology   (United Kingdom)

^b UNIVERSITY OF SZEGED   (Hungary)

Author keywords

BK virus; Polyomavirus associated nephropathy; Renal allograft; Renal biopsy; Ultrastructure

Indexed keywords

PARAFFIN; VIRUS T ANTIGEN;

BASEMENT MEMBRANE; CELL NUCLEUS INCLUSION BODY; CLINICAL FEATURE; CYTOPATHOGENIC EFFECT; DIFFERENTIAL DIAGNOSIS; DISEASE SEVERITY; FIBROSING ALVEOLITIS; GLOMERULUS; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATION; KIDNEY ALLOGRAFT; KIDNEY BIOPSY; KIDNEY DISEASE; KIDNEY FUNCTION; KIDNEY INFECTION; KIDNEY TUBULE EPITHELIUM; LEYDIG CELL; MICROSCOPY; NEPHRON; POLYOMA VIRUS; PRIORITY JOURNAL; REVIEW; SIMIAN VIRUS 40; TREATMENT FAILURE; VIREMIA; VIRUS REPLICATION;

BK VIRUS; DIAGNOSIS, DIFFERENTIAL; HUMANS; KIDNEY; KIDNEY DISEASES; KIDNEY TRANSPLANTATION; POLYOMAVIRUS INFECTIONS; TRANSPLANTATION, HOMOLOGOUS;

EID: 33750482222     PISSN: 17458323     EISSN: 17458331     Source Type: Journal    
DOI: 10.1038/ncpneph0319     Document Type: Review

References (31)

1. Zuckerman AJ et al. (Eds; 2004) Principles and Practice of Clinical Virology, edn 5. Chichester: John Wiley and Sons Ltd
2. Pappo O et al. (1996) Human polyoma virus infection of renal allografts: histopathologic diagnosis, clinical significance, and literature review. Mod Pathol 9: 105-109
3. Boldorini R et al. (2005) Kidney and urinary tract polyomavirus infection and distribution: molecular biology investigation of 10 consecutive autopsies. Arch Pathol Lab Med 129: 69-73
4. Randhawa P et al. (2005) A comparative study of BK and JC virus infections in organ transplant recipients. J Med Virol 77: 238-243
5. Kazory A et al. (2003) The first case of JC virus allograft nephropathy. Transplantation 76: 1653-1655
6. Howell DN et al. (1999) Diagnosis and management of BK polyomavirus interstitial nephritis in renal transplant recipients. Transplantation 68: 1279-1288
7. Coleman DV et al. (1978) Human polyomavirus (BK) infection and ureteric stenosis in renal allograft recipients. J Clin Pathol 31: 338-347
8. Ramos E et al. (2002) BK virus nephropathy diagnosis and treatment: experience at the University of Maryland Renal Transplant Program. Clin Transplant 13: 143-153
9. Binet I et al. (1999) Polyomavirus disease under new immunosuppressive drugs: a cause of renal graft dysfunction and graft loss. Transplantation 67: 918-922
10. Humar A (2006) Reactivation of viruses in solid organ transplant patients receiving cytomegalovirus prophylaxis. Transplantation 27 (Suppl): S9-S14
11. Drachenberg CB et al. (2003) BK polyoma virus allograft nephropathy: ultrastructural features from viral cell entry to lysis. Am J Transplant 3: 1383-1392
12. Drachenberg CB et al. (2005) Polyomavirus disease in renal transplantation: review of pathological findings and diagnostic methods. Hum Pathol 36: 1245-1255
13. Namba Y et al. (2005) Prevalence, characteristics, and outcome of BK virus nephropathy in Japanese renal transplant patients: analysis in protocol and episode biopsies. Clin Transplant 19: 97-101
14. Mengel M et al. (2003) Incidence of polyomavirus-nephropathy in renal allografts: influence of modern immunosuppressive drugs. Nephrol Dial Transplant 18: 1190-1196
15. Bressollette-Bodin C et al. (2005) A prospective longitudinal study of BK virus infection in 104 renal transplant recipients. Am J Transplant 5: 1926-1933
16. Nickeleit V et al. (2003) Polyomavirus nephropathy: morphology, pathophysiology, and clinical management. Curr Opin Nephrol Hypertens 12: 599-605
17. Hirsch HH et al. (2005) Polyomavirus-associated nephropathy in renal transplantation: interdisciplinary analyses and recommendations. Transplantation 79: 1277-1286
18. Trofe J et al. (2006) Polyomavirus-associated nephropathy: update of clinical management in kidney transplant patients. Transplant Infect Dis 8: 76-85
19. Josephson MA et al. (2006) Polyomavirus-associated nephropathy: update on antiviral strategies. Transplant Infect Dis 8: 95-101
20. Boldorini R et al. (2005) Periodic assessment of urine and serum by cytology and molecular biology as a diagnostic tool for BK virus nephropathy in renal transplant patients. Acta Cytol 49: 235-243
21. Vera-Sempere FJ et al. (2005) Polymerase chain reaction detection of BK virus and monitoring of BK nephropathy in renal transplant recipients at the University Hospital La Fe. Transplant Proc 37: 3770-3773
22. Ramos E et al. (2004) Retransplantation in patients with graft loss caused by polyoma virus nephropathy. Transplantation 77: 131-133
23. Womer KL et al. (2006) Preemptive retransplantation for BK virus nephropathy: successful outcome despite active viremia. Am J Transplant 6: 7-9
24. Nickeleit V et al. (2000) BK-virus nephropathy in renal transplants-tubular necrosis, MHC-class II expression and rejection in a puzzling game. Nephrol Dial Transplant 15: 324-332
25. Nickeleit V et al. (1999) Polyomavirus infection of renal allograft recipients: from latent infection to manifest disease. J Am Soc Nephrol 10: 1080-1089
26. Ahuja M et al. (2001) Polyoma virus infection after renal transplantation: use of immunostaining as a guide to diagnosis. Transplantation 71: 896-899
27. Celik B et al. (2004) Glomerular changes in BK virus nephropathy. Hum Pathol 35: 367-370
28. Nickeleit V and Mihatsch MJ (2005) Histologic changes in polyomavirus allograft nephropathy. In Updates in Nephropathology and Transplantation; Proceedings of the Nephropathology Pre-congress Meeting of the 20th European Congress of Pathology; Paris, 36-40 (Eds Vizjak A et al.) Ljubljana: Institute of Pathology, University of Ljubljana
29. Gaber LW et al. (2006) Clinical utility of histological features of polyomavirus allograft nephropathy. Transplantation 82: 196-204
30. Racusen LC et al. (2003) Antibody mediated rejection criteria-an addition to the Banff '97 classification of renal allograft rejection. Am J Transplant 3: 1-7
31. Solez K et al. (1993) International standardization of criteria for the histologic diagnosis of renal allograft rejection: the Banff working classification of kidney transplant pathology. Kidney Int 44: 411-422