An RpoH-like heat shock sigma factor is involved in stress response and virulence in Brucella melitensis 16M

Journal of Bacteriology

Volumn 188, Issue 21, 2006, Pages 7707-7710

  Delory, Marie ^a   Hallez, Régis ^a   Letesson, Jean Jacques ^a   De Bolle, Xavier ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN; HYDROGEN PEROXIDE; SIGMA FACTOR; SIGMA FACTOR RPOH; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; BACTERIUM CULTURE; BRUCELLA MELITENSIS; CULTURE MEDIUM; DISEASE MODEL; GENE EXPRESSION REGULATION; GENE MUTATION; GENOME ANALYSIS; NONHUMAN; NULL ALLELE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RPOD GENE; RPOE1 GENE; RPOE2 GENE; RPOH1 GENE; RPOH2 GENE; RPON GENE; STRESS;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; ANTI-BACTERIAL AGENTS; BLOTTING, WESTERN; BRUCELLA MELITENSIS; BRUCELLOSIS; CELL LINE; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; GENE DELETION; GENE EXPRESSION REGULATION, BACTERIAL; HEAT-SHOCK PROTEINS; HUMANS; HYDROGEN PEROXIDE; MACROPHAGES; MICE; MICE, INBRED BALB C; MUTAGENESIS, INSERTIONAL; SIGMA FACTOR; TEMPERATURE; VIRULENCE; VIRULENCE FACTORS;

BRUCELLA MELITENSIS; BRUCELLA MELITENSIS 16M;

EID: 33750480906     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.00644-06     Document Type: Article

References (15)

1. Delrue, R. M., C. Deschamps, S. Leonard, C. Nijskens, I. Danese, J. M. Schaus, S. Bonnet, J. Ferooz, A. Tiber, X. De Bolle, and J. J. Letesson. 2005. A quorum-sensing regulator controls expression of both the type IV secretion system and the flagellar apparatus of Brucella melitensis. Cell. Microbiol. 7:1151-1161.
2. Detilleux, P. G., B. L. Deyoe, and N. F. Cheville. 1990. Penetration and intracellular growth of Brucella abortus in nonphagocytic cells in vitro. Infect. Immun. 58:2320-2328.
3. Elzer, P. H., R. W. Phillips, M. E. Kovach, K. M. Peterson, and R. M. Roop. 1994. Characterization and genetic complementation of a Brucella abortus high-temperature-requirement A (htrA) deletion mutant. Infect. Immun. 62:4135-4139.
4. Fang, F. C., S. J. Libby, N. A. Buchmeier, P. C. Loewen, J. Switala, J. Harwood, and D. G. Guiney. 1992. The alternative sigma factor katF (rpoS) regulates Salmonella virulence. Proc. Natl. Acad. Sci. USA 89:11978-11982.
5. Fretin, D., A. Fauconnier, S. Kohler, S. Halling, S. Leonard, C. Nijskens, J. Ferooz, P. Lestrate, R. M. Delrue, I. Danese, J. Vandenhaute, A. Tiber, X. De Bolle, and J. J. Letesson. 2005. The sheathed flagellum of Brucella melitensis is involved in persistence in a murine model of infection. Cell. Microbiol. 7:687-698.
6. Gorham, H. C., S. J. McGowan, P. R. Robson, and D. A. Hodgson. 1996. Light-induced carotenogenesis in Myxococcus xanthus: light-dependent membrane sequestration of ECF sigma factor CarQ by anti-sigma factor CarR. Mol. Microbiol. 19:171-186.
7. Guzman-Verri, C., L. Manterola, A. Sola-Landa, A. Parra, A. Cloeckaert, J. Garin, J. P. Gorvel, I. Moriyon, E. Moreno, and I. Lopez-Goni. 2002. The two-component system BvrR/BvrS essential for Brucella abortus virulence regulates the expression of outer membrane proteins with counterparts in members of the Rhizobiaceae. Proc. Natl. Acad. Sci. USA 99:12375-12380.
8. Haine, V., A. Sinon, F. Van Steen, S. Rousseau, M. Dozot, P. Lestrate, C. Lambert, J. J. Letesson, and X. De Bolle. 2005. Systematic targeted mutagenesis of Brucella melitensis 16M reveals a major role for GntR regulators in the control of virulence. Infect. Immun. 73:5578-5586.
9. Lestrate, P., A. Dricot, R. M. Delrue, C. Lambert, V. Martinelli, X. De Bolle, J. J. Letesson, and A. Tibor. 2003. Attenuated signature-tagged mutagenesis mutants of Brucella melitensis identified during the acute phase of infection in mice. Infect. Immun. 71:7053-7060.
10. Loewen, P. C., and R. Hengge-Aronis. 1994. The role of the sigma factor sigma S (KatF) in bacterial global regulation. Annu. Rev. Microbiol. 48:53-80.
11. Nadon, C. A., B. M. Bowen, M. Wiedmann, and K. J. Boor. 2002. Sigma B contributes to PrfA-mediated virulence in Listeria monocytogenes. Infect. Immun. 70:3948-3952.
12. O'Callaghan, D., C. Cazevieille, A. Allardet-Servent, M. L. Boschiroli, G. Bourg, V. Foulongne, P. Frutos, Y. Kulakov, and M. Ramuz. 1999. A homologue of the Agrobacterium tumefaciens VirB and Bordetella pertussis PtI type IV secretion systems is essential for intracellular survival of Brucella suis. Mol. Microbiol. 33:1210-1220.
13. Parsot, C., and J. J. Mekalanos. 1990. Expression of ToxR, the transcriptional activator of the virulence factors in Vibrio cholerae, is modulated by the heat shock response. Proc. Natl. Acad. Sci. USA 87:9898-9902.
14. Roop, R. M., J. M. Gee, G. T. Robertson, J. M. Richardson, W. L. Ng, and M. E. Winkler. 2003. Brucella stationary-phase gene expression and virulence. Annu. Rev. Microbiol. 57:57-76.
15. Rouot, B., M. T. Alvarez-Martinez, C. Marius, P. Menanteau, L. Guilloteau, R. A. Boigegrain, R. Zumbihl, D. O'Callaghan, N. Domke, and C. Baron. 2003. Production of the type IV secretion system differs among Brucella species as revealed with VirB5- and VirB8-specific antisera. Infect. Immun. 71:1075-1082.