메뉴 건너뛰기




Volumn 18, Issue 5-6, 2006, Pages 505-509

Levosimendan: A new option in acute cardiac failure

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; DRUG METABOLITE; LEVOSIMENDAN; N [4 (1,4,5,6 TETRAHYDRO 4 METHYL 6 OXO 3 PYRIDAZINYL)PHENYL]ACETAMIDE; OR 1855; OXYGEN; PHOSPHODIESTERASE III INHIBITOR; PLACEBO; TROPONIN C; UNCLASSIFIED DRUG;

EID: 33750475576     PISSN: 17426731     EISSN: 17426723     Source Type: Journal    
DOI: 10.1111/j.1742-6723.2006.00871.x     Document Type: Review
Times cited : (4)

References (25)
  • 1
    • 2442649996 scopus 로고    scopus 로고
    • A rational approach for the treatment of acute heart failure: Current strategies and future options
    • Sharma M, Teerlink JR. A rational approach for the treatment of acute heart failure: current strategies and future options. Curr. Opin. Cardiol. 2004; 19: 254-63.
    • (2004) Curr. Opin. Cardiol. , vol.19 , pp. 254-263
    • Sharma, M.1    Teerlink, J.R.2
  • 2
    • 0034669441 scopus 로고    scopus 로고
    • Hemodynamic and neurohumoral effects of continuous infusion of levosimendan in patients with congestive heart failure
    • Nieminen MS, Akkila J, Hasenfuss G et al. Hemodynamic and neurohumoral effects of continuous infusion of levosimendan in patients with congestive heart failure. J. Am. Coll. Cardiol. 2000; 36: 1903-12.
    • (2000) J. Am. Coll. Cardiol. , vol.36 , pp. 1903-1912
    • Nieminen, M.S.1    Akkila, J.2    Hasenfuss, G.3
  • 3
    • 0036116421 scopus 로고    scopus 로고
    • Levosimendan: A new era for inodilator therapy for heart failure?
    • Cleland JG, McGowan J. Levosimendan: a new era for inodilator therapy for heart failure? Curr. Opin. Cardiol. 2002; 17: 257-65.
    • (2002) Curr. Opin. Cardiol. , vol.17 , pp. 257-265
    • Cleland, J.G.1    McGowan, J.2
  • 4
    • 0035088001 scopus 로고    scopus 로고
    • Levosimendan increases diastolic coronary flow in isolated guinea-pig heart by opening ATP-sensitive potassium channels
    • Kaheinen P, Pollesello P, Levijoki J et al. Levosimendan increases diastolic coronary flow in isolated guinea-pig heart by opening ATP-sensitive potassium channels. J. Cardiovasc. Pharmacol. 2001; 37: 367-74. Important basic research elucidating the mechanism of the vasodilator effects of levosimendan.
    • (2001) J. Cardiovasc. Pharmacol. , vol.37 , pp. 367-374
    • Kaheinen, P.1    Pollesello, P.2    Levijoki, J.3
  • 5
    • 0343049171 scopus 로고    scopus 로고
    • Comparison of the vasorelaxing effect of cromakalim and the new inodilator, levosimendan, in human isolated portal vein
    • Pataricza J, Hohn J, Petri A et al. Comparison of the vasorelaxing effect of cromakalim and the new inodilator, levosimendan, in human isolated portal vein. J. Pharm. Pharmacol. 2000; 52: 213-17.
    • (2000) J. Pharm. Pharmacol. , vol.52 , pp. 213-217
    • Pataricza, J.1    Hohn, J.2    Petri, A.3
  • 6
    • 0031976338 scopus 로고    scopus 로고
    • Effects of a new calcium sensitizer, levosimendan, on haemodynamics, coronary blood flow and myocardial substrate utilization early after coronary artery bypass grafting
    • Lilleberg J, Nieminen MS, Akkila J et al. Effects of a new calcium sensitizer, levosimendan, on haemodynamics, coronary blood flow and myocardial substrate utilization early after coronary artery bypass grafting. Eur. Heart J. 1998; 19: 660-8.
    • (1998) Eur. Heart J. , vol.19 , pp. 660-668
    • Lilleberg, J.1    Nieminen, M.S.2    Akkila, J.3
  • 7
    • 0030955524 scopus 로고    scopus 로고
    • The role of cAMP-and cGMP-dependent protein kinases in the cardiac actions of the new calcium sensitizer, levosimendan
    • Haikala H, Kaheinen P, Levijoki J et al. The role of cAMP-and cGMP-dependent protein kinases in the cardiac actions of the new calcium sensitizer, levosimendan. Cardiovasc. Res. 1997; 34: 536-46.
    • (1997) Cardiovasc. Res. , vol.34 , pp. 536-546
    • Haikala, H.1    Kaheinen, P.2    Levijoki, J.3
  • 8
    • 0034739460 scopus 로고    scopus 로고
    • Acute hemodynamic and clinical effects of levosimendan in patients with severe heart failure
    • Slawsky MT, Colucci WS, Gottlieb SS et al. Acute hemodynamic and clinical effects of levosimendan in patients with severe heart failure. Circulation 2000; 102: 2222-7.
    • (2000) Circulation , vol.102 , pp. 2222-2227
    • Slawsky, M.T.1    Colucci, W.S.2    Gottlieb, S.S.3
  • 9
    • 16344362711 scopus 로고    scopus 로고
    • Effects of intravenous levosimendan on human coronary vasomotor regulation, left ventricular wall stress, and myocardial oxygen uptake
    • Michaels AD, McKeown B, Kostal M et al. Effects of intravenous levosimendan on human coronary vasomotor regulation, left ventricular wall stress, and myocardial oxygen uptake. Circulation 2005; 111: 1504-9.
    • (2005) Circulation , vol.111 , pp. 1504-1509
    • Michaels, A.D.1    McKeown, B.2    Kostal, M.3
  • 10
    • 0029585067 scopus 로고
    • Pharmacokinetics of levosimendan in healthy volunteers and patients with congestive heart failure
    • Sandell E-P, Hayha M, Antila S et al. Pharmacokinetics of levosimendan in healthy volunteers and patients with congestive heart failure. J. Cardiovasc. Pharmacol. 1995; 26 (Suppl. 1): 557-62.
    • (1995) J. Cardiovasc. Pharmacol. , vol.26 , Issue.SUPPL. 1 , pp. 557-562
    • Sandell, E.-P.1    Hayha, M.2    Antila, S.3
  • 12
    • 0031775152 scopus 로고    scopus 로고
    • Integrated pharmacokinetics and pharmacodynamics of the novel calcium sensitizer levosimendan as assessed by systolic time intervals
    • Sundberg S, Antila S, Scheinin H, Hayha M, Virtanen M, Lehtonen L. Integrated pharmacokinetics and pharmacodynamics of the novel calcium sensitizer levosimendan as assessed by systolic time intervals. Int. J. Clin. Pharmacol. Ther. 1998; 36: 629-35.
    • (1998) Int. J. Clin. Pharmacol. Ther. , vol.36 , pp. 629-635
    • Sundberg, S.1    Antila, S.2    Scheinin, H.3    Hayha, M.4    Virtanen, M.5    Lehtonen, L.6
  • 13
    • 1942455382 scopus 로고    scopus 로고
    • Pharmacokinetics of levosimendan and its circulating metabolites in patients with heart failure after an extended continuous infusion of levosimendan
    • Antila S, Kivikko M, Lehtonen L et al. Pharmacokinetics of levosimendan and its circulating metabolites in patients with heart failure after an extended continuous infusion of levosimendan. Br. J. Clin. Pharmacol. 2004; 57: 412-15.
    • (2004) Br. J. Clin. Pharmacol. , vol.57 , pp. 412-415
    • Antila, S.1    Kivikko, M.2    Lehtonen, L.3
  • 14
    • 5644302941 scopus 로고    scopus 로고
    • Pharmacokinetics of levosimendan and its active metabolite OR-1896 in rapid and slow acetylators
    • Antila S, Pesonen U, Lehtonen L et al. Pharmacokinetics of levosimendan and its active metabolite OR-1896 in rapid and slow acetylators. Eur. J. Pharm. Sci. 2004; 23: 213-22.
    • (2004) Eur. J. Pharm. Sci. , vol.23 , pp. 213-222
    • Antila, S.1    Pesonen, U.2    Lehtonen, L.3
  • 15
    • 0037422531 scopus 로고    scopus 로고
    • Sustained hemodynamic effects of intravenous levosimendan
    • Kivikko M, Lehtonen L, Colucci WS. Sustained hemodynamic effects of intravenous levosimendan. Circulation 2003; 107: 81-6.
    • (2003) Circulation , vol.107 , pp. 81-86
    • Kivikko, M.1    Lehtonen, L.2    Colucci, W.S.3
  • 16
    • 4444363048 scopus 로고    scopus 로고
    • Pharmacodynamics and pharmacokinetics of oral levosimendan and its metabolites in patients with severe congestive heart failure: A dosing interval study
    • Poder P, Eha J, Sundberg S et al. Pharmacodynamics and pharmacokinetics of oral levosimendan and its metabolites in patients with severe congestive heart failure: a dosing interval study. J. Clin. Pharmacol. 2004; 44: 1143-50.
    • (2004) J. Clin. Pharmacol. , vol.44 , pp. 1143-1150
    • Poder, P.1    Eha, J.2    Sundberg, S.3
  • 17
    • 0036764821 scopus 로고    scopus 로고
    • Safety and efficacy of a novel calcium sensitizer, levosimendan, in patients with left ventricular failure due to an acute myocardial infarction. A randomized, placebo-controlled, double-blind study (RUSSLAN)
    • Moiseyev VS, Poder P, Andrejevs N et al. Safety and efficacy of a novel calcium sensitizer, levosimendan, in patients with left ventricular failure due to an acute myocardial infarction. A randomized, placebo-controlled, double-blind study (RUSSLAN). Eur. Heart J. 2002; 23: 1422-32 18.
    • (2002) Eur. Heart J. , vol.23 , pp. 1422-3218
    • Moiseyev, V.S.1    Poder, P.2    Andrejevs, N.3
  • 18
    • 0037142946 scopus 로고    scopus 로고
    • Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study): A randomized doubleblind trial
    • Steering Committee and Investigators of the Levosimendan Infusion versus Dobutamine (LIDO) Study
    • Steering Committee and Investigators of the Levosimendan Infusion versus Dobutamine (LIDO) Study. Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study): a randomized doubleblind trial. Lancet 2002; 360: 196-202.
    • (2002) Lancet , vol.360 , pp. 196-202
  • 19
    • 33750436820 scopus 로고    scopus 로고
    • REVIVE II trial investigators REVIVE II: Multicenter placebo-controlled trial of levosimendan on clinical status in acutely decompensated heart failure
    • Packer M. REVIVE II trial investigators REVIVE II: multicenter placebo-controlled trial of levosimendan on clinical status in acutely decompensated heart failure. Circulation 2005; 112: 3363.
    • (2005) Circulation , vol.112 , pp. 3363
    • Packer, M.1
  • 20
    • 33750489992 scopus 로고    scopus 로고
    • The SURVIVE-W trial: Comparison of dobutamine and levosimendan on survival in acute decompensated heart failure
    • Mebazaa A, Packer M. The SURVIVE-W trial: comparison of dobutamine and levosimendan on survival in acute decompensated heart failure. Circulation 2005; 112: 3364.
    • (2005) Circulation , vol.112 , pp. 3364
    • Mebazaa, A.1    Packer, M.2
  • 21
    • 4444226530 scopus 로고    scopus 로고
    • Levosimendan in patients with cardiogenic shock undergoing surgical revascularization: A case series
    • Lehmann A, Lang J, Boldt J, Isgro F, Kiessling AH. Levosimendan in patients with cardiogenic shock undergoing surgical revascularization: a case series. Med. Sci. Monitor. 2004; 10: MT89-93.
    • (2004) Med. Sci. Monitor. , vol.10
    • Lehmann, A.1    Lang, J.2    Boldt, J.3    Isgro, F.4    Kiessling, A.H.5
  • 22
    • 14944348020 scopus 로고    scopus 로고
    • Comparison between dobutamine and levosimendan for management of post resuscitation myocardial dysfunction
    • Huang L, Weil MH, Tang, WC, Sun SJ, Wang JL. Comparison between dobutamine and levosimendan for management of post resuscitation myocardial dysfunction. Crit. Care Med. 2005; 33: 487-91.
    • (2005) Crit. Care Med. , vol.33 , pp. 487-491
    • Huang, L.1    Weil, M.H.2    Tang, W.C.3    Sun, S.J.4    Wang, J.L.5
  • 24
    • 0036137181 scopus 로고    scopus 로고
    • Pharmacodynamics and safety of a new calcium sensitizer, levosimendan, and its metabolites during an extended infusion in patients with severe heart failure
    • Kivikko M, Antila S, Eha J et al. Pharmacodynamics and safety of a new calcium sensitizer, levosimendan, and its metabolites during an extended infusion in patients with severe heart failure. J. Clin. Pharmacol. 2002; 42: 43-51.
    • (2002) J. Clin. Pharmacol. , vol.42 , pp. 43-51
    • Kivikko, M.1    Antila, S.2    Eha, J.3
  • 25
    • 0037276509 scopus 로고    scopus 로고
    • Intravenous levosimendan treatment is cost-effective compared with dobutamine in severe low-output heart failure: An analysis based on the international LIDO trial
    • Cleland JG, Takala A, Apajasalo M, Zethraeus N, Kobelt G. Intravenous levosimendan treatment is cost-effective compared with dobutamine in severe low-output heart failure: an analysis based on the international LIDO trial. Eur. J. Heart Fail. 2003; 5: 101-8.
    • (2003) Eur. J. Heart Fail. , vol.5 , pp. 101-108
    • Cleland, J.G.1    Takala, A.2    Apajasalo, M.3    Zethraeus, N.4    Kobelt, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.