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Volumn 54, Issue 20, 2006, Pages 7924-7928

Iron uptake by Caco-2 cells from NaFeEDTA and FeSO4: Effects of ascorbic acid, pH, and a Fe(II) chelating agent

Author keywords

Caco 2 cells; Ferritin; Iron bioavailability; Iron uptake; NaFeEDTA

Indexed keywords

ASCORBIC ACID; EDETIC ACID; FE(III) EDTA; FE(III)-EDTA; FERRIC ION; FERRITIN; FERROUS ION; FERROUS SULFATE; IRON; IRON CHELATING AGENT;

EID: 33750474466     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf061036z     Document Type: Article
Times cited : (48)

References (42)
  • 1
    • 0042421989 scopus 로고    scopus 로고
    • Iron intake and regulation: Implications for iron deficiency and iron overload
    • Swanson, C. A. Iron intake and regulation: Implications for iron deficiency and iron overload. Alcohol 2003, 30, 99-102.
    • (2003) Alcohol , vol.30 , pp. 99-102
    • Swanson, C.A.1
  • 2
    • 0008498062 scopus 로고    scopus 로고
    • Iron
    • Bowman, B. A., Russel, R. M., Eds.; ILSI Press: Washington, DC
    • Yip, R. Iron. In Present Knowledge in Nutrition; Bowman, B. A., Russel, R. M., Eds.; ILSI Press: Washington, DC, 2001; pp 311-328.
    • (2001) Present Knowledge in Nutrition , pp. 311-328
    • Yip, R.1
  • 3
    • 0024500271 scopus 로고
    • Comparison of in vitro, animal, and clinical determinations of iron bioavailability: International Nutritional Anemia Consultative Group Task Force report on iron bioavailability
    • Forbes, A. L.; Arnaud, M. J.; Chichester, C. O.; Cook, J. D.; Harrison, B. N.; Hurrell, R. F.; Kahn, S. G.; Morris, E. R.; Tanner, J. T.; Whittaker, P. Comparison of in vitro, animal, and clinical determinations of iron bioavailability: International Nutritional Anemia Consultative Group Task Force report on iron bioavailability. Am. J. Clin. Nutr. 1989, 49, 225-238.
    • (1989) Am. J. Clin. Nutr. , vol.49 , pp. 225-238
    • Forbes, A.L.1    Arnaud, M.J.2    Chichester, C.O.3    Cook, J.D.4    Harrison, B.N.5    Hurrell, R.F.6    Kahn, S.G.7    Morris, E.R.8    Tanner, J.T.9    Whittaker, P.10
  • 4
    • 0030920395 scopus 로고    scopus 로고
    • Preventing iron deficiency through food fortification
    • Hurrell, R. F. Preventing iron deficiency through food fortification. Nutr. Rev. 1997, 55, 210-222.
    • (1997) Nutr. Rev. , vol.55 , pp. 210-222
    • Hurrell, R.F.1
  • 5
    • 12244299903 scopus 로고    scopus 로고
    • Acute toxicity of carbonyl iron and sodium iron EDTA compared with ferrous sulfate in young rats
    • Whittaker, P.; Ali, S. F.; Imam, S. Z.; Dunkel, V. C. Acute toxicity of carbonyl iron and sodium iron EDTA compared with ferrous sulfate in young rats. Regul. Toxicol. Pharmacol. 2002, 36, 280-286.
    • (2002) Regul. Toxicol. Pharmacol. , vol.36 , pp. 280-286
    • Whittaker, P.1    Ali, S.F.2    Imam, S.Z.3    Dunkel, V.C.4
  • 6
    • 0034024608 scopus 로고    scopus 로고
    • Estimation of nonheme-iron bioavailability from meal composition
    • Reddy, M. B.; Hurrell, R. F.; Cook, J. D. Estimation of nonheme-iron bioavailability from meal composition. Am. J. Clin. Nutr. 2000, 71, 937-943.
    • (2000) Am. J. Clin. Nutr. , vol.71 , pp. 937-943
    • Reddy, M.B.1    Hurrell, R.F.2    Cook, J.D.3
  • 7
    • 0035192683 scopus 로고    scopus 로고
    • Effect of ascorbic acid intake on nonheme-iron absorption from a complete diet
    • Cook, J. D.; Reddy, M. B. Effect of ascorbic acid intake on nonheme-iron absorption from a complete diet. Am. J. Clin. Nutr. 2001, 73, 93-98.
    • (2001) Am. J. Clin. Nutr. , vol.73 , pp. 93-98
    • Cook, J.D.1    Reddy, M.B.2
  • 8
    • 0024366196 scopus 로고
    • Iron absorption and phenolic compounds: Importance of different phenolic structures
    • Brune, M.; Rossander, L.; Hallberg, L. Iron absorption and phenolic compounds: Importance of different phenolic structures. Eur. J. Clin. Nutr. 1989, 43, 547-557.
    • (1989) Eur. J. Clin. Nutr. , vol.43 , pp. 547-557
    • Brune, M.1    Rossander, L.2    Hallberg, L.3
  • 9
    • 0024582557 scopus 로고
    • Iron absorption: No intestinal adaptation to a high-phytate diet
    • Brune, M.; Rossander, L.; Hallberg, L. Iron absorption: No intestinal adaptation to a high-phytate diet. Am. J. Clin. Nutr. 1989, 49, 542-545.
    • (1989) Am. J. Clin. Nutr. , vol.49 , pp. 542-545
    • Brune, M.1    Rossander, L.2    Hallberg, L.3
  • 10
    • 0028046307 scopus 로고
    • Iron bioavailability studied in infants: The influence of phytic acid and ascorbic acid in infant formulas based on soy isolate
    • Davidsson, L.; Galan, P.; Kastenmayer, P.; Cherouvrier, F.; Juillerat, M. A.; Hercberg, S.; Hurrell, R. F. Iron bioavailability studied in infants: The influence of phytic acid and ascorbic acid in infant formulas based on soy isolate. Pediatr. Res. 1994, 36, 816-822.
    • (1994) Pediatr. Res. , vol.36 , pp. 816-822
    • Davidsson, L.1    Galan, P.2    Kastenmayer, P.3    Cherouvrier, F.4    Juillerat, M.A.5    Hercberg, S.6    Hurrell, R.F.7
  • 11
    • 0017682853 scopus 로고
    • Fe(III)-EDTA complex as iron fortification
    • Layrisse, M.; Martinez-Torres, C. Fe(III)-EDTA complex as iron fortification. Am. J. Clin. Nutr. 1977, 30, 1166-1174.
    • (1977) Am. J. Clin. Nutr. , vol.30 , pp. 1166-1174
    • Layrisse, M.1    Martinez-Torres, C.2
  • 13
    • 0025353551 scopus 로고
    • Effect of EDTA on the bioavailability to rats of fortification iron used in Egyptian balady bread
    • Whittaker, P.; Vanderveen, J. E. Effect of EDTA on the bioavailability to rats of fortification iron used in Egyptian balady bread. Br. J. Nutr. 1990, 63, 587-595.
    • (1990) Br. J. Nutr. , vol.63 , pp. 587-595
    • Whittaker, P.1    Vanderveen, J.E.2
  • 15
    • 33750470525 scopus 로고    scopus 로고
    • GRAS No. GRN 000178, WEB access
    • GRAS No. GRN 000178, 2006; WEB access: http://www.cfsan.fda.gov/~rdb/opa- gras.html.
    • (2006)
  • 16
    • 21344452773 scopus 로고    scopus 로고
    • Studies on the effectiveness of NaFeEDTA-fortified soy sauce in controlling iron deficiency: A population-based intervention trial
    • discussion 18-19
    • Chen, J.; Zhao, X.; Zhang, X.; Yin, S.; Piao, J.; Huo, J.; Yu, B.; Qu, N.; Lu, Q.; Wang, S.; Chen, C. Studies on the effectiveness of NaFeEDTA-fortified soy sauce in controlling iron deficiency: A population-based intervention trial. Food Nutr. Bull. 2005, 26, 177-186; discussion 18-19.
    • (2005) Food Nutr. Bull. , vol.26 , pp. 177-186
    • Chen, J.1    Zhao, X.2    Zhang, X.3    Yin, S.4    Piao, J.5    Huo, J.6    Yu, B.7    Qu, N.8    Lu, Q.9    Wang, S.10    Chen, C.11
  • 17
    • 0016284330 scopus 로고
    • Iron supplementation in Thai fish-sauce
    • Garby, L.; Areekul, S. Iron supplementation in Thai fish-sauce. Ann. Trop. Med. Parasitol. 1974, 68, 467-476.
    • (1974) Ann. Trop. Med. Parasitol. , vol.68 , pp. 467-476
    • Garby, L.1    Areekul, S.2
  • 18
    • 0029066316 scopus 로고
    • Fortification of sugar with iron sodium ethylenediaminotetraacetate (FeNaEDTA) improves iron status in semirural Guatemalan populations
    • Viteri, F. E.; Alvarez, E.; Batres, R.; Torun, B.; Pineda, O.; Mejia, L. A.; Sylvi, J. Fortification of sugar with iron sodium ethylenediaminotetraacetate (FeNaEDTA) improves iron status in semirural Guatemalan populations. Am. J. Clin. Nutr. 1995, 61, 1153-1163.
    • (1995) Am. J. Clin. Nutr. , vol.61 , pp. 1153-1163
    • Viteri, F.E.1    Alvarez, E.2    Batres, R.3    Torun, B.4    Pineda, O.5    Mejia, L.A.6    Sylvi, J.7
  • 19
    • 28244458880 scopus 로고    scopus 로고
    • Recent advances in intestinal iron transport
    • Anderson, G. J.; Frazer, D. M. Recent advances in intestinal iron transport. Curr. Gastroenterol. Rep. 2005, 7, 365-372.
    • (2005) Curr. Gastroenterol. Rep. , vol.7 , pp. 365-372
    • Anderson, G.J.1    Frazer, D.M.2
  • 20
    • 0024848726 scopus 로고
    • Mechanisms and regulation of intestinal uptake and transfer of iron
    • Flanagan, P. R. Mechanisms and regulation of intestinal uptake and transfer of iron. Acta Paediatr. Scand. Suppl. 1989, 361, 21-30.
    • (1989) Acta Paediatr. Scand. Suppl. , vol.361 , pp. 21-30
    • Flanagan, P.R.1
  • 25
    • 0032189574 scopus 로고    scopus 로고
    • Iron binding by tannic acid: Effects of selected ligands
    • South, P. K.; Miller, D. D. Iron binding by tannic acid: effects of selected ligands. Food Chem. 1998, 63, 167-172.
    • (1998) Food Chem. , vol.63 , pp. 167-172
    • South, P.K.1    Miller, D.D.2
  • 27
    • 0031658047 scopus 로고    scopus 로고
    • Caco-2 cell ferritin formation predicts nonradiolabeled food iron availability in an in vitro digestion/Caco-2 cell culture model
    • Glahn, R. P.; Lee, O. A.; Yeung, A.; Goldman, M. I.; Miller, D. D. Caco-2 cell ferritin formation predicts nonradiolabeled food iron availability in an in vitro digestion/Caco-2 cell culture model. J. Nutr. 1998, 128, 1555-1561.
    • (1998) J. Nutr. , vol.128 , pp. 1555-1561
    • Glahn, R.P.1    Lee, O.A.2    Yeung, A.3    Goldman, M.I.4    Miller, D.D.5
  • 28
    • 4744367457 scopus 로고    scopus 로고
    • An in vitro digestion/Caco-2 cell culture system accurately predicts the effects of ascorbic acid and polyphenolic compounds on iron bioavailability in humans
    • Yun, S.; Habicht, J. P.; Miller, D. D.; Glahn, R. P. An in vitro digestion/Caco-2 cell culture system accurately predicts the effects of ascorbic acid and polyphenolic compounds on iron bioavailability in humans. J. Nutr. 2004, 134, 2717-2721.
    • (2004) J. Nutr. , vol.134 , pp. 2717-2721
    • Yun, S.1    Habicht, J.P.2    Miller, D.D.3    Glahn, R.P.4
  • 29
    • 8344285839 scopus 로고    scopus 로고
    • Calcium, zinc, and iron bioavailabilities from a commercial human milk fortifier: A comparison study
    • Etcheverry, P.; Wallingford, J. C.; Miller, D. D.; Glahn, R. P. Calcium, zinc, and iron bioavailabilities from a commercial human milk fortifier: A comparison study. J. Dairy Sci. 2004, 87, 3629-3637.
    • (2004) J. Dairy Sci. , vol.87 , pp. 3629-3637
    • Etcheverry, P.1    Wallingford, J.C.2    Miller, D.D.3    Glahn, R.P.4
  • 30
    • 0030034230 scopus 로고    scopus 로고
    • Caco-2 cell iron uptake from meat and casein digests parallels in vivo studies: Use of a novel in vitro method for rapid estimation of iron bioavailability
    • Glahn, R. P.; Wien, E. M.; Van Campen, D. R.; Miller, D. D. Caco-2 cell iron uptake from meat and casein digests parallels in vivo studies: Use of a novel in vitro method for rapid estimation of iron bioavailability. J. Nutr. 1996, 126, 332-339.
    • (1996) J. Nutr. , vol.126 , pp. 332-339
    • Glahn, R.P.1    Wien, E.M.2    Van Campen, D.R.3    Miller, D.D.4
  • 31
    • 0347986910 scopus 로고    scopus 로고
    • A low-molecular-weight factor in human milk whey promotes iron uptake by Caco-2 cells
    • Etcheverry, P.; Miller, D. D.; Glahn, R. P. A low-molecular-weight factor in human milk whey promotes iron uptake by Caco-2 cells. J. Nutr. 2004, 134, 93-98.
    • (2004) J. Nutr. , vol.134 , pp. 93-98
    • Etcheverry, P.1    Miller, D.D.2    Glahn, R.P.3
  • 32
    • 0029027292 scopus 로고
    • Bathophenanthrolene disulfonic acid and sodium dithionite effectively remove surface-bound iron from Caco-2 cell monolayers
    • Glahn, R. P.; Gangloff, M. B.; Van Campen, D. R.; Miller, D. D.; Wien, E. M.; Norvell, W. A. Bathophenanthrolene disulfonic acid and sodium dithionite effectively remove surface-bound iron from Caco-2 cell monolayers. J. Nutr. 1995, 125, 1833-1840.
    • (1995) J. Nutr. , vol.125 , pp. 1833-1840
    • Glahn, R.P.1    Gangloff, M.B.2    Van Campen, D.R.3    Miller, D.D.4    Wien, E.M.5    Norvell, W.A.6
  • 33
    • 0027174668 scopus 로고
    • A comparison of bathophenanthrolinedisulfonic acid and ferrozine as chelators of iron(II) in reduction reactions
    • Cowart, R. E.; Singleton, F. L.; Hind, J. S. A comparison of bathophenanthrolinedisulfonic acid and ferrozine as chelators of iron(II) in reduction reactions. Anal. Biochem. 1993, 277, 151-155.
    • (1993) Anal. Biochem. , vol.277 , pp. 151-155
    • Cowart, R.E.1    Singleton, F.L.2    Hind, J.S.3
  • 35
    • 0025988250 scopus 로고
    • Assessment of dietary determinants of nonheme-iron absorption in humans and rats
    • Reddy, M. B.; Cook, J. D. Assessment of dietary determinants of nonheme-iron absorption in humans and rats. Am. J. Clin. Nutr. 1991, 54, 723-728.
    • (1991) Am. J. Clin. Nutr. , vol.54 , pp. 723-728
    • Reddy, M.B.1    Cook, J.D.2
  • 36
    • 0642287958 scopus 로고    scopus 로고
    • Mechanisms and regulation of intestinal iron absorption
    • Morgan, E. H.; Oates, P. S. Mechanisms and regulation of intestinal iron absorption. Blood Cells Mol. Dis. 2002, 29, 384-399.
    • (2002) Blood Cells Mol. Dis. , vol.29 , pp. 384-399
    • Morgan, E.H.1    Oates, P.S.2
  • 37
    • 0022641146 scopus 로고
    • Effect of ascorbic acid on iron absorption from different types of meals. Studies with ascorbic-acid-rich foods and synthetic ascorbic acid given in different amounts with different meals
    • Hallberg, L.; Brune, M.; Rossander, L. Effect of ascorbic acid on iron absorption from different types of meals. Studies with ascorbic-acid-rich foods and synthetic ascorbic acid given in different amounts with different meals. Hum. Nutr. Appl. Nutr. 1986, 40, 97-113.
    • (1986) Hum. Nutr. Appl. Nutr. , vol.40 , pp. 97-113
    • Hallberg, L.1    Brune, M.2    Rossander, L.3
  • 38
    • 0013768548 scopus 로고
    • Effect of chelating agents on radioiron absorption and distribution in rats in vivo
    • Hopping, J. M.; Ruliffson, W. S. Effect of chelating agents on radioiron absorption and distribution in rats in vivo. Am. J. Physiol. 1963, 205, 885-889.
    • (1963) Am. J. Physiol. , vol.205 , pp. 885-889
    • Hopping, J.M.1    Ruliffson, W.S.2
  • 39
    • 0033967027 scopus 로고    scopus 로고
    • Safety assessment of iron EDTA [sodium iron (Fe(3+)) ethylenediaminetetraacetic acid]: Summary of lexicological, fortification and exposure data
    • Heimbach, J.; Rieth, S.; Mohamedshah, F.; Slesinski, R.; Samuel-Fernando, P.; Sheehan, T.; Dickmann, R.; Borzelleca, J. Safety assessment of iron EDTA [sodium iron (Fe(3+)) ethylenediaminetetraacetic acid]: Summary of lexicological, fortification and exposure data. Food Chem. Toxicol. 2000, 38, 99-111.
    • (2000) Food Chem. Toxicol. , vol.38 , pp. 99-111
    • Heimbach, J.1    Rieth, S.2    Mohamedshah, F.3    Slesinski, R.4    Samuel-Fernando, P.5    Sheehan, T.6    Dickmann, R.7    Borzelleca, J.8
  • 40
    • 4444279028 scopus 로고    scopus 로고
    • Iron absorption from NaFeEDTA is downregulated in iron-loaded rats
    • Yeung, C. K.; Zhu, L.; Glahn, R. P.; Miller, D. D. Iron absorption from NaFeEDTA is downregulated in iron-loaded rats. J. Nutr. 2004, 134, 2270-2274.
    • (2004) J. Nutr. , vol.134 , pp. 2270-2274
    • Yeung, C.K.1    Zhu, L.2    Glahn, R.P.3    Miller, D.D.4
  • 41
    • 11244256504 scopus 로고    scopus 로고
    • Inhibition of iron uptake from iron salts and chelates by divalent metal cations in intestinal epithelial cells
    • Yeung, C. K.; Glahn, R. P.; Miller, D. D. Inhibition of iron uptake from iron salts and chelates by divalent metal cations in intestinal epithelial cells. J. Agric. Food Chem. 2005, 53, 132-136.
    • (2005) J. Agric. Food Chem. , vol.53 , pp. 132-136
    • Yeung, C.K.1    Glahn, R.P.2    Miller, D.D.3
  • 42
    • 0000320006 scopus 로고    scopus 로고
    • Valence state of iron in the presence of ascorbic acid and ethylenediaminetetraacetic acid
    • Hsieh, Y.-H. P.; Hsieh, Y. P. Valence state of iron in the presence of ascorbic acid and ethylenediaminetetraacetic acid. J. Agric. Food Chem. 1997, 45, 1126-1129.
    • (1997) J. Agric. Food Chem. , vol.45 , pp. 1126-1129
    • Hsieh, Y.-H.P.1    Hsieh, Y.P.2


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