Optimal decision indices for R&D project evaluation in the pharmaceutical industry: Pearson index versus Gittins index

European Journal of Operational Research

Volumn 177, Issue 2, 2006, Pages 1105-1112

  Talias, Michael A ^a  

^a JACOBS UNIVERSITY BREMEN   (Germany)

Author keywords

Gittins index; Pearson index; Project prioritization; Research and development in pharmaceutical industry; Statistical decision theory

Indexed keywords

DECISION THEORY; DRUG PRODUCTS PLANTS; MANAGERS; PROJECT MANAGEMENT; RESEARCH AND DEVELOPMENT MANAGEMENT; STATISTICAL METHODS;

GITTINS INDEX; PEARSON INDEX; PROJECT PRIORITIZATION; STATISTICAL DECISION THEORY;

DECISION MAKING;

EID: 33750473344     PISSN: 03772217     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejor.2006.01.011     Document Type: Article

References (14)

1. Bergman S.W., and Gittins J.C. Statistical Methods for Pharmaceutical Research Planning (1985), Marcel Dekker
2. Gittins J.C. Bandit processes and dynamic allocation indices. Journal of the Royal Statistical Society Series B 14 (1979) 148-177
3. Gittins J.C. Quantitative methods in the planning of pharmaceutical research. Drug Information Journal 30 (1996) 479-487
4. Gittins J.C. Why crash pharmaceutical research?. R&D Management 27 1 (1997) 79-85
5. Gittins, J.C., Jones, D.M., 1974. A dynamic allocation index for sequential design of experiments. In: Gani, J.M., Sarkadi, K., Vincze, I. (Eds.), Progress in Statistics, pp. 241-266.
6. Neyman J., and Pearson E.S. On the probability of the most efficient tests of statistical hypotheses. Philosophical Transactions of the Royal Society of London Series A 231 (1933) 289-337
7. Pearson A. The use of ranking formulae in R&D projects. R&D Management 2 (1972) 69-73
8. Regan P.J., and Senn S. Project evaluation in drug development: A case study in collaboration. In: French S., and Smith J.Q. (Eds). The Practice of Bayesian Analysis (1997), Arnold 259-277
9. Senn S.J. Some statistical issues in project prioritization in the pharmaceutical industry. Statistics in Medicine 15 1 (1996) 2689-2702
10. Senn S.J. Statistical issues in drug development. Statistics in Practice (1997), John Wiley & Sons
11. Senn S.J. Further statistical issues in project prioritization in the pharmaceutical industry. Drug Information Journal 32 (1998) 253-259
12. Wald A. Sequential tests of statistical hypothesis. Annals of Mathematical Statistics 16 (1945) 117-186
13. Wald A., and Wolfowitz J. Optimum character of the sequential probability ratio test. Annals of Mathematical Statistics 19 (1948) 326-339
14. Zipfel A. Modeling the probability-cost-profitability architecture of portfolio management in the pharmaceutical industry. Drug Information Journal 37 (2003) 185-205