Antitumor and antimetastatic effects of betulonic acid amides in mice with transplantable Lewis carcinoma

Bulletin of Experimental Biology and Medicine

Volumn 142, Issue 1, 2006, Pages 69-72

  Sorokina, I V ^a   Tolstikova, T G ^a   Zhukova, N A ^a   Petrenko, N I ^a   Uzenkova, N V ^a   Shul'ts, E E ^a   Popova, N A ^b  

^a N N VOROZHTSOV NOVOSIBIRSK INSTITUTE OF ORGANIC CHEMISTRY   (Russian Federation)

^b INSTITUTE OF CYTOLOGY AND GENETICS   (Russian Federation)

Author keywords

2 and 3 3 oxo 20(29) lupen 28 oilamino propionic acid; Antimetastatic effect; Antitumor effect; Betulonic acid; Transplantable tumor

Indexed keywords

2 [3 OXO 20(29)LUPEN 28 OILAMINO]PROPIONIC ACID; 2 [3 OXO 20(29)LUPEN 28 OILAMINO]PROPIONIC ACID METHYL ESTER; 3 [3 OXO 20(29)LUPEN 28 OILAMINO]PROPIONIC ACID; 3 [3 OXO 20(29)LUPEN 28 OILAMINO]PROPIONIC ACID METHYL ESTER; ANTIMETASTATIC AGENT; ANTINEOPLASTIC AGENT; BETULONIC ACID AMIDE DERIVATIVE; TRITERPENOID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG SYNTHESIS; LEWIS CARCINOMA; LUNG METASTASIS; METASTASIS POTENTIAL; METHYLATION; MOUSE; NONHUMAN; SINGLE DRUG DOSE; TREATMENT RESPONSE;

ALANINE; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, LEWIS LUNG; MALE; MICE; MICE, INBRED C57BL; NEOPLASM METASTASIS; OLEANOLIC ACID;

EID: 33750470388     PISSN: 00074888     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10517-006-0294-x     Document Type: Article

References (11)

1. G. G. Avtandilov, Medical Morphometry [in Russian], Moscow (1990).
2. E. D. Gol'dberg and E. P. Zueva, Plant Preparations in Combination Therapy of Malignant Neoplasms [in Russian], Tomsk (2000), p. 42.
3. N. I. Petrenko, N. V. Elantseva, V. Z. Petukhova, et al., Khim. Prirodn. Soed., No. 4, 276-283 (2002).
4. A. G. Pokrovskii, O. A. Plyasunova, T. N. I'icheva, et al., Khimiya Interesakh Ustoichivogo Razvitiya, 9, 485-491 (2001).
5. E. A. Semenova, O. A. Plyasunova, N. I. Petrenko, et al., Dokl. Akad. Nauk, 391, No. 4, 556-558 (2003).
6. I. V. Sorokina, T. G. Tolstikova, E. B. Bubnova, et al., Nauch. Vestn. Tyumensk. Med. Akad. Bioantioksidanty, No. 1, 60-61 (2003).
7. I. V. Sorokina, T. G. Tolstikova, N. A. Zhukova, et al., Dokl. Akad. Nauk, 399, No. 2, 274-277 (2004).
8. R. H. Cichewicz and S. A. Kouzi, Med. Res. Rev., 24, 90-114 (2004).
9. H. J. Jeong, H. B. Chai, S. Y. Park, et al., Bioorgan. Med. Chem. Lett., 9, 1201-1204 (1999).
10. D. S. Kim, J. M. Pezzuto, and E. Pisha, Ibid., 8, 1707-1712 (1998).
11. A. M. Nadureira, J. R. Ascenso, L. Valdeira, et al., Nat. Prod. Res., 17, 375-380 (2003).