Capillary microscopy and hemorheology in children during antiepileptic monotherapy with carbamazepine and valproate

Seizure

Volumn 15, Issue 8, 2006, Pages 606-609

  Gerstner, Thorsten ^a   Woelfing, Christina ^a   Witsch, Michael ^a   Longin, Elke ^a   Bell, Nellie ^a   König, Stephan ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Antiepileptic drugs; Capillary density; Capillary microscopy; Plasma viscosity

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; CHOLESTEROL; HOMOCYSTEINE; LIPID; VALPROIC ACID;

ADOLESCENT; ARTICLE; BLOOD FLOW VELOCITY; BLOOD RHEOLOGY; BLOOD VESSEL COMPLIANCE; BLOOD VESSEL DIAMETER; CAPILLARY DENSITY; CAPILLARY FLOW; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; DYSLIPIDEMIA; ENDOTHELIUM INJURY; EPILEPSY; ERYTHROCYTE AGGREGATION; ERYTHROCYTE KINETICS; FEMALE; HEART INFARCTION; HEART LEFT VENTRICLE HYPERTROPHY; HOSPITAL DEPARTMENT; HUMAN; HYPERCHOLESTEROLEMIA; INCIDENCE; LIPID COMPOSITION; MAJOR CLINICAL STUDY; MALE; MICROCIRCULATION; MICROSCOPY; MONOTHERAPY; NON INVASIVE MEASUREMENT; NORMAL VALUE; PERIPHERAL VASCULAR DISEASE; PLASMA VISCOSITY; PRESCRIPTION; PRIORITY JOURNAL; SCHOOL CHILD; SKIN CAPILLARY; STROKE; VASCULAR DISEASE; VASCULAR ENDOTHELIUM;

ADOLESCENT; ANTICONVULSANTS; BLOOD FLOW VELOCITY; CAPILLARIES; CARBAMAZEPINE; CEREBELLAR CORTEX; CHILD; EPILEPSY; FEMALE; HEMORHEOLOGY; HUMANS; MALE; MICROCIRCULATION; MICROSCOPY; VALPROIC ACID;

EID: 33750464837     PISSN: 10591311     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.seizure.2006.08.006     Document Type: Article

References (22)

1. Koenig S.A., Knolle J., Friedewald S., Koelfen W., Longin E., Lenz T., et al. Effects of valproic acid, carbamazepine, and phenobarbitone on the fatty acid composition of erythrocyte membranes in children. Epilepsia 44 (2003) 708-711
2. Karabiber H., Sonmezgoz E., Ozerol E., Yakinci C., Otlu B., and Yologlu S. Effects of valproate and carbamazepine on serum levels of homocysteine, vitamin B12, and folic acid. Brain Dev 25 (2003) 113-115
3. de Chadarevian J.P., Legido A., Miles D.K., and Katsetos C.D. Epilepsy, atherosclerosis, myocardial infarction, and carbamazepine. J Child Neurol 18 (2003) 150-151
4. Li X., Breteler M.M., de Bruyne M.C., Meinardi H., Hauser W.A., and Hofman A. Vascular determinants of epilepsy: the Rotterdam Study. Epilepsia 38 November (11) (1997) 1216-1220
5. Renkin E.M. Cellular aspects of transvascular exchange: a 40-year perspective. Microcirculation 1 (1994) 157-167
6. Lombard W.P. The blood pressure in the arterioles. Capillaries and small veins of the human skins. Am J Physiol 29 (1912) 335
7. Bollinger A., Butti P., Barras J.P., Trachsler H., and Siegenthaler W. Red blood cell velocity in nailfold capillaries of man measured by a television microscopy technique. Microvasc Res 7 (1974) 61-72
8. Ostergren J., and Fagrell B. Skin capillary blood cell velocity in patients with arterial obliterative disease and polycythaemia: a disturbed reactive hyperaemia response. Clin Physiol 5 (1985) 35-43
9. Tooke J.E., Lins P.E., Ostergren J., Adamson U., and Fagrell B. The effects of intravenous insulin infusion on skin microcirculatory flow in Type 1 diabetes. Int J Microcirc Clin Exp 4 (1985) 69-83
10. Fagrell B. Microcirculatory methods for the clinical assessment of hypertension, hypotension, and ischemia. Ann Biomed Eng 14 (1986) 163-173
11. Sobaniec-Lotowska M., Sobaniec W., and Augustynowicz A. Morphometric analysis of the cerebellar cortex capillaries in the course of experimental valproate encephalopathy and after chronic exposure to sodium valproate using transmission electron microscopy. Folia Neuropathol 39 (2001) 277-280
12. Sechi G., Casu A.R., Rosati G., Spanu A., Deserra F., Nuvoli S., et al. Cerebral and cerebellar diaschisis following carbamazepine therapy. Prog Neuropsychopharmacol Biol Psychiatry 19 (1995) 889-901
13. Valmier J., Touchon J., Blayac J.P., and Baldy-Moulinier M. Initiation of carbamazepine therapy in partial epilepsy: a regional cerebral blood flow study. Epilepsy Res 5 (1990) 229-234
14. Jung F., Berthold R., Wappler M., Kiesewetter H., and Wenzel E. Reference range of capillary geometric values in apparently healthy probands between 6 and 65 years of age. Vasa Suppl 20 (1987) 109-112
15. Engelmann A. Capillary microscopy in children and adolescents. Medical dissertation. University Heidelberg; 1997.
16. Olkon D.M. Epilepsy of the angiospastic variety in monozygotic twins. Arch Neurol Psychiat 25 (1930) 1111
17. Eiris J., Novo-Rodriguez M.I., Del Rio M., Meseguer P., Del Rio M.C., and Castro-Gago M. The effects on lipid and apolipoprotein serum levels of long-term carbamazepine, valproic acid and phenobarbital therapy in children with epilepsy. Epilepsy Res 41 (2000) 1-7
18. Nikolaos T., Stylianos G., Chryssoula N., Irini P., Christos M., Dimitrios T., et al. The effect of long-term antiepileptic treatment on serum cholesterol (TC, HDL, LDL) and triglyceride levels in adult epileptic patients on monotherapy. Med Sci Monit 10 (2004) 50-52
19. Loscher W., and Honack D. Valproate and its major metabolite E-2-en-valproate induce different effects on behaviour and brain monoamine metabolism in rats. Eur J Pharmacol 299 (1996) 61-67
20. Purdy R.E., Julien R.M., Fairhurst A.S., and Terry M.D. Effect of carbamazepine on the in vitro uptake and release of norepinephrine in adrenergic nerves of rabbit aorta and in whole brain synaptosomes. Epilepsia 18 (1977) 251-257
21. Hauser E., Seidl R., Freilinger M., Male C., and Herkner K. Hematologic manifestations and impaired liver synthetic function during valproate monotherapy. Brain Dev 18 (1996) 105-109
22. Hauptmann A., and Myerson A. Study of finger capillaries in schizophrenia and manic depression psychoses. J Nerv Ment Dis 108 (1948) 91-108