Prenatal GABAB1 and GABAB2 receptors: Cellular and subcellular organelle localization in early fetal rat cortical neurons

Synapse

Volumn 60, Issue 8, 2006, Pages 557-566

  Li, S P ^a   Lee, H Y ^a   Park, M S ^a   Bahk, J Y ^a   Chung, B C ^b   Kim, M O ^a  

^a Gyeongsang National University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

Author keywords

Cellular and subcellular localization; Cortex; Early fetal rat brain; GABAB receptors; Immunogold

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID B1 RECEPTOR; 4 AMINOBUTYRIC ACID B2 RECEPTOR; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; GABA TYPE B RECEPTOR, SUBUNIT 1; GABRB2 PROTEIN, RAT;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; BRAIN CELL; BRAIN CORTEX; BRAIN MITOCHONDRION; CELL MIGRATION; CELL ORGANELLE; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENDRITE; FEMALE; FETUS; FETUS DEVELOPMENT; GABAERGIC SYSTEM; GESTATIONAL AGE; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NERVE ENDING; NEUROEPITHELIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SYNAPSE; WESTERN BLOTTING; ANIMAL; CELL DIFFERENTIATION; CELL MOTION; ENDOPLASMIC RETICULUM; METABOLISM; MITOCHONDRION; NERVE CELL; PHYSIOLOGY; PRENATAL DEVELOPMENT; STEM CELL; SYNAPTIC TRANSMISSION; SYNAPTOSOME; ULTRASTRUCTURE;

ANIMALS; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CEREBRAL CORTEX; DENDRITES; ENDOPLASMIC RETICULUM; FEMALE; GAMMA-AMINOBUTYRIC ACID; MALE; MICROSCOPY, IMMUNOELECTRON; MITOCHONDRIA; NEURONS; ORGANELLES; PRESYNAPTIC TERMINALS; RATS; RECEPTORS, GABA-A; RECEPTORS, GABA-B; STEM CELLS; SYNAPTIC TRANSMISSION;

EID: 33750460933     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20332     Document Type: Article

References (37)

1. Altman LG, Schneider BG, Papermaster DS. 1984. Rapid embedding of tissues in lowicryl K4M for immunoelectron microscopy. J Histochem Cytochem 32:1217-1233.
2. Bayer SA, Altman J. 1994. Development: Neurogenesis and neuronal migration in the rat central nervous system. In: Paxinos G, editor. The rat nervous system. Orlando: Academic Press. p 944-950.
3. Behar TN, Schaffner AE, Colton CA, Somogyi R, Olah Z, Lehel C, Barker JL. 1994. GABA-induced chemokinesis and NGF-induced chemotaxis of embryonic spinal cord neurons. J Neurosci 14:29-38.
4. Behar TN, Li YX, Tran HT, Ma W, Dunlap V, Scott C, Barker JL. 1996. GABA stimulates chemotaxis and chemokinesis of embryonic cortical neurons via calcium-dependent mechanisms. J Neurosci 16:1808-1818.
5. Behar TN, Schaffner AE, Scott CA, O'Connell C, Barker JL. 1998. Differential response of cortical plate and ventricular zone cells to GABA as a migration stimulus. J Neurosci 18:6378-6387.
6. Behar TN, Schaffner AE, Scott CA, Greene CL, Barker JL. 2000. GABA receptor antagonists modulate postmitotic cell migration in slice cultures of embryonic rat cortex. Cereb Cortex 10:899-909.
7. A, NMDA and AMPA receptors: A developmentally regulated "ménage a trios." Trends Neurosci 20:523-529.
8. Chebib M, Johnston GA. 1999. The 'ABC' of GABA receptors: A brief review. Clin Exp Pharmacol Physiol 26:937-940.
9. Cherubini E, Gaiarsa JL, Ben-Ari Y. 1991. GABA: An excitatory transmitter in early postnatal life. Trends Neurosci 14:515-519.
10. Cherubini E, Martina M, Sciancalepore M, Strata F. 1998. GABA excites immature CA3 pyramidal cells through bicuculline-sensitive and-insensitive chloride dependent receptors. Perspect Dev Neurobiol 5:289-304.
11. Cobas A, Fairen A, Alvarez-Bolado G, Sanchez MP. 1991. Prenatal development of the intrinsic neurons of the rat neocortex: A comparative study of the distribution of GABA-immunoreactive cells and the GABAA receptor. Neuroscience 40:375-397.
12. Doerr-Schott J, Lichte CM. 1986. A triple ultrastructural immunogold staining method. J Histochem Cytochem 34:1101-1104.
13. B2 receptor proteins in the rat Cerebellum. Mol Brain Res 83:72-80.
14. Jones K, Borowsky B, Tamm J, Craig D, Durkin M, Dai M, Johnson M, Gunwaldsen C, Huang L, Tang S, Shen Q, Salon J, Morse K, Laz T, Smith K, Nagarathnam D, Noble S, Branchek T, Gerald C. 1998. GABA(B) receptors function as heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2. Nature 396:674-679.
15. B receptor subtypes assemble into functional heteromeric complexes. Nature 396:683-687.
16. B2 receptor mRNAs on the development of the rat central nervous system. Brain Res Dev Brain Res 143:47-55.
17. Kulik A, Nakadate K, Nyiri G, Notomi T, Malitschek B, Bettler B, Shigemoto R. 2002. Distinct lacalization of GABAB receptors relative to synaptic sites in the rat cerebellum and ventraobasal thalamus. Eur J Neurosci 15:291-307.
18. Lauder JM, Han VK, Henderson P, Verdoorn T, Towle AC. 1986. Prenatal ontogeny of the GABAergic system in the rat brain: An immunocytochemical study. Neuroscience 19:465-493.
19. Laurie DJ, Wisden W, Seeburg PH. 1992. The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development. J Neurosci 12:4151-4172.
20. Li H, Tornberg J, Kaila K, Airaksinen MS, Rivera C. 2002. Patterns of cation-chloride cotransporter expression during embryonic rodent CNS development. Eur J Neurosci 16:2358-2370.
21. Lopez-Bendito G, Shigemoto R, Kulik A, Paulsen O, Fairen A, Lujan R. 2002. Expression and distribution of metabotropic GABA receptor subtypes GABABR1 and GABABR2 during rat neocortical development. Eur J Neurosci 15:1766-1778.
22. Lopez-Bendito G, Lujan R, Shigemoto R, Ganter P, Paulsen O, Molnar Z. 2003. Blockade of GABA(B) receptors alters the tangential migration of cortical neurons. Cereb Cortex 13:932-942.
23. Lo Turco JJ, Kriegstein AR. 1991. Clusters of coupled neuroblasts in embryonic neocortex. Science 252:563-566.
24. Lo Turco JJ, Owens DF, Heath MJ, Davis MB, Kriegstein AR. 1995. GABA and glutamate depolarize cortical progenitor cells and inhibit DNA synthesis. Neuron 15:1287-1298.
25. Maric D, Liu QY, Maric I, Chaudry S, Chang YH, Smith SV, Sieghart W, Fritschy JM, Barker JL. 2001. GABA expression dominates neuronal lineage progression in the embryonic rat neocortex and facilitates neurite outgrowth via GABA(A) autoreceptor/Cl-channels. J Neurosci 21:2343-2360.
26. Marin O, Rubenstein JL. 2001. A long, remarkable journey: Tangential migration in the telencephalon. Nat Rev Neurosci 2:780-790.
27. B receptors-The first 7TM heterodimers. Trends Pharmacol Sci 20: 396-399.
28. Owens DF, Boyce LH, Davis MB, Kriegstein AR. 1996. Excitatory GABA responses in embryonic and neonatal cortical slices demonstrated by gramicidin perforated-patch recordings and calcium imaging. J Neurosci 16:6414-6423.
29. Owens DF, Kriegstein AR. 1998. Patterns of intracellular calcium fluctuation in precursor cells of the neocortical ventricular zone. J Neurosci 18:5374-5388.
30. Poulter MO, Barker JL, O'Carroll AM, Lolait SJ, Mahan LC. 1992. Differential and transient expression of GABAA receptor α-subunit mRNAs in the developing rat CNS. J Neurosci 12:2888-2900.
31. Poulter MO, Barker JL, O'Carroll AM, Lolait SJ, Mahan LC. 1993. Co-existent expression of GABAA receptor β 2, β 3 and γ 2 subunit messenger RNAs during embryogenesis and early postnatal development of the rat central nervous system. Neuroscience 53:1019-1033.
32. Schaffner AE, Behar T, Nadi S, Smallwood V, Barker JL. 1993. Quantitative analysis of transient GABA expression in embryonic and early post-natal rat spinal cord neurons. Brain Res Dev Brain Res 72:265-276.
33. Simeone TA, Donevan SD, Rho JM. 2003. Molecular biology and ontogeny of γ-aminobutyric acid (GABA) receptors in the mammalian central nervous system. J Child Neurol 18:39-48.
34. Strata F, Cherubini E. 1994. Transient expression of a novel type of GABA response in rat CA3 hippocampal neurones during development. J Physiol 480:493-503.
35. Van Eden CG, Mrzljak L, Voorn P, Uylings HB. 1989. Prenatal development of GABA-ergic neurons in the neocortex of the rat. J Comp Neurol 289:213-227.
36. Van Kesteren RE, Spencer GE. 2003. The role of neurotransmitters in neurite outgrowth and synapse formation. Rev Neurosci 14:217-231.
37. White JH, McIllhinney RA, Wise A, Ciruela F, Chan WY, Emson PC, Billinton A, Marshall FH. 2000. The GABAB receptor interacts directly with the related transcription factors CREB2 and ATFx. Proc Natl Acad Sci 97:13967-13972.