Evaluation of 3-carboxy-4(1H)-quinolones as inhibitors of human protein kinase CK2

Journal of Medicinal Chemistry

Volumn 49, Issue 22, 2006, Pages 6443-6450

  Golub, Andriy G ^a   Yakovenko, Olexander Ya ^a   Bdzhola, Volodymyr G ^a   Sapelkin, Vladislav M ^a   Zien, Piotr ^b   Yarmoluk, Sergiy M ^a  

^a INSTITUTE OF MOLECULAR BIOLOGY AND GENETICS   (Ukraine)

^b Department of Oncology ^*  (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

3 CARBOXY 4(1H) QUINOLONE; 4 OXO 1,4 DIHYDROBENZO[H]QUINOLINE 3 CARBOXYLIC ACID; 5,6,8 TRICHOLORO 4 OXO 1,4 DIHYDROQUINOLINE 3 CARBOXYLIC ACID; ADENOSINE TRIPHOSPHATE; CASEIN KINASE II INHIBITOR; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING COMPETITION; CALCULATION; DRUG EFFECT; DRUG EFFICACY; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; EVALUATION; IC 50; STRUCTURE ANALYSIS;

ADENOSINE TRIPHOSPHATE; CASEIN KINASE II; COMPUTER SIMULATION; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; HYDROGEN BONDING; INDICATORS AND REAGENTS; LIGANDS; MODELS, MOLECULAR; QUINOLONES; RECEPTORS, DRUG; RECOMBINANT PROTEINS; SOFTWARE; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 33750456981     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm050048t     Document Type: Article

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