Synthesis of silk fibroin-insulin bioconjugates and their characterization and activities in vivo

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 79, Issue 2, 2006, Pages 275-283

  Zhang, Yu Qing ^a   Ma, Yan ^a   Xia, Yun Yue ^b   Shen, Wei De ^a   Mao, Jian Ping ^a   Zha, Xin Min ^c   Shirai, Koji ^c   Kiguchi, Kenji ^c  

^a SOOCHOW UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^c SHINSHU UNIVERSITY   (Japan)

Author keywords

Bioconjugates; Crosslinking; ELISA; Insulin; Silk fibroin

Indexed keywords

AMINO ACIDS; INSULIN; PHARMACODYNAMICS; PHYSICAL CHEMISTRY; SILK; SYNTHESIS (CHEMICAL); TEXTILE FIBERS;

BIOCONJUGATES; ELISA; SILK FIBROIN;

ORGANIC POLYMERS;

AMINO ACID; BOVINE SERUM ALBUMIN; GLUTARALDEHYDE; INSULIN; LYSINE; SERINE; SILK FIBROIN;

ALLOXAN DIABETES MELLITUS; AMINO ACID COMPOSITION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGENICITY; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DRUG CONJUGATION; DRUG DETERMINATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG STABILITY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOGENICITY; IN VITRO STUDY; IN VIVO STUDY; INSULIN TREATMENT; MALE; MOLECULAR WEIGHT; MOLECULE; NONHUMAN; PHYSICAL CHEMISTRY; QUANTITATIVE ANALYSIS; RABBIT; RAT; SERUM;

ANIMALS; BOMBYX; CROSS-LINKING REAGENTS; FIBROINS; INSULIN; MALE; RABBITS; RATS;

NATURAL FIBERS; SILK;

EID: 33750442915     PISSN: 00219304     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.30539     Document Type: Article

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