Substrate specificity of three viral thymidine kinases (TK): Vaccinia virus TK, feline herpesvirus TK, and canine herpesvirus TK

Nucleosides, Nucleotides and Nucleic Acids

Volumn 25, Issue 9-11, 2006, Pages 1189-1192

  Solaroli, N ^a   Johansson, M ^a   Balzarini, J ^b   Karlsson, A ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Gene therapy; Nucleoside analog; Nucleoside kinases; Suicide gene

Indexed keywords

DEOXYCYTIDINE; THYMIDINE KINASE; THYMIDINE KINASE 1;

ARTICLE; CONTROLLED STUDY; ENZYME SPECIFICITY; HERPES SIMPLEX VIRUS 1; HERPES VIRUS; NONHUMAN; VACCINIA VIRUS;

ESCHERICHIA COLI; GENE THERAPY; GENETIC VECTORS; HERPESVIRIDAE; HERPESVIRUS 1, CANID; HERPESVIRUS 1, HUMAN; MODELS, CHEMICAL; NUCLEOSIDE-PHOSPHATE KINASE; PHOSPHORYLATION; SPECIES SPECIFICITY; SUBSTRATE SPECIFICITY; THYMIDINE KINASE; VACCINIA VIRUS; VIRAL PROTEINS;

CANID HERPESVIRUS 1; FELID HERPESVIRUS 1; MAMMALIA; SIMPLEXVIRUS; VACCINIA VIRUS;

EID: 33750437781     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770600894451     Document Type: Article

References (2)

1. Remond, M.; Sheldrick, P.; Lebreton, F.; Foulon, T. Sequence of the canine herpesvirus thymidine kinase gene: taxon-preferred amino acid residues in the alphaherpesviral thymidine kinases. Virus Res. 1995, 39, 341-354.
2. Nunberg, J.H.; Wright, D.K.; Cole, G.E.; Petrovskis, E.A.; Post, L.E.; Compton, T.; Gilbert, J.H. Identification of the thymidine kinase gene of feline herpesvirus: use of degenerate oligonucleotides in the polymerase chain reaction to isolate herpesvirus gene homologs. J. Virol. 1989, 63, 3240-3249.