Thymidine phosphorylase is noncompetitively inhibited by 5′-O-trityl-inosine (KIN59) and related compounds

Nucleosides, Nucleotides and Nucleic Acids

Volumn 25, Issue 9-11, 2006, Pages 975-980

  Liekens, S ^a   Balzarini, J ^a   Hernandez A I ^b   De Clercq, E ^a   Priego, E M ^b   Camarasa, M J ^b   Perez Perez M J ^b  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b INSTITUTO DE QUÍMICA MÉDICA   (Spain)

Author keywords

Angiogenesis; Cancer; Nucleoside metabolism; Platelet derived endothelial cell growth factor (PD ECGF); Thymidine phosphorylase

Indexed keywords

5' O TRITYL INOSINE; INOSINE DERIVATIVE; KIN 59; PLATELET DERIVED ENDOTHELIAL CELL GROWTH FACTOR; PYRIMIDINE; THYMIDINE; THYMIDINE PHOSPHORYLASE; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; CHICK; CHORIOALLANTOIS; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME BINDING; ENZYME INHIBITION; ESCHERICHIA COLI; HUMAN; IC 50; KINETICS; NONHUMAN; NUCLEOTIDE BINDING SITE;

ALLOSTERIC SITE; ANIMALS; CHICKENS; CHORION; ENZYME INHIBITORS; ESCHERICHIA COLI; HUMANS; INHIBITORY CONCENTRATION 50; INOSINE; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; PHOSPHATES; PYRIMIDINES; THYMIDINE PHOSPHORYLASE; TRITYL COMPOUNDS;

BACTERIA (MICROORGANISMS);

EID: 33750431748     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770600888925     Document Type: Article

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