Involvement of intramuscular interstitial cells of Cajal in neuroeffector transmission in the gastrointestinal tract

Journal of Physiology

Volumn 576, Issue 3, 2006, Pages 675-682

  Ward, Sean M ^a   Sanders, Kenton M ^a  

^a UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROTRANSMITTER; NEUTRALIZING ANTIBODY; STEM CELL FACTOR; SNARE PROTEIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; SYNAPTOTAGMIN; SYNTAXIN;

ARTICLE; CELL FUNCTION; CELL STRUCTURE; CELLULAR DISTRIBUTION; CHOLINERGIC TRANSMISSION; DIGESTIVE SYSTEM ELECTROPHYSIOLOGY; FUNCTIONAL ANATOMY; GAP JUNCTION; GASTROINTESTINAL TRACT; INTERSTITIAL CELL OF CAJAL; INTESTINE INNERVATION; MUSCLE FIBER MEMBRANE POTENTIAL; NEUROMUSCULAR FUNCTION; NEUROTRANSMISSION; NEUROTRANSMITTER RELEASE; NITRERGIC NERVE; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; POSTSYNAPTIC MEMBRANE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; STOMACH ANTRUM; STOMACH FUNDUS; STOMACH MUSCLE; SYNAPTIC TRANSMISSION; ACTION POTENTIAL; ANIMAL CELL; CHOLINERGIC NERVE CELL; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; GASTROINTESTINAL TISSUE; INTESTINE MUSCLE; MYENTERIC PLEXUS; NERVE ENDING; NITRERGIC NERVE CELL;

ANIMALS; BIOLOGICAL CLOCKS; ENTERIC NERVOUS SYSTEM; GASTROINTESTINAL TRACT; MICE; MOTOR NEURONS; MUSCLE, SMOOTH; NEUROEFFECTOR JUNCTION; SYNAPTIC TRANSMISSION;

EID: 33750423041     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2006.117390     Document Type: Article

References (52)

1. Aguado F, Majo G, Ruiz-Montasell B, Llorens J, Marsal J & Blasi J (1999). Syntaxin 1A and 1B display distinct distribution patterns in the rat peripheralnervous system. Neuroscience 88, 437-446.
2. Aoki C, Miko I, Oviedo H, Mikeladze-Dvali T, Alexandre L, Sweeney N & Bredt DS (2001). Electron microscopic immunocytochemical detection of PSD-95, PSD-93, SAP-102, and SAP-97 at postsynaptic, presynaptic, and nonsynaptic sites of adult and neonatal rat visual cortex. Synapse 40, 239-257.
3. Beckett EAH, Horiguchi K, Khoyi M, Sanders KM & Ward SM (2002). Loss of enteric motor neurotransmission in the gastric fundus of Sl/Sl (d) mice. J Physiol 543, 871-887.
4. Beckett EAH, McGeough CA, Sanders KM & Ward SM (2003). Pacing of interstitial cells of Cajal in the murine gastric antrum: Neurally mediated and direct stimulation. J Physiol 553, 545-559.
5. Beckett EAH, Takeda Y, Yanase H, Sanders KM & Ward SM (2005). Synaptic specializations exist between enteric motor nerves and interstitial cells of Cajal in the murine stomach. J Comp Neurol 493, 193-206.
6. Boaro SN, Soares JC & Konig B (1998). Comparative structural analysis of neuromuscular junctions in mice at different ages. Anat Anz 180, 173-179.
7. Burns AJ, Lomax AEJ, Torihashi S, Sanders KM & Ward SM (1996). Interstitial cells of Cajal mediate inhibitory neurotransmission in the stomach. Proc Natl Acad Sci U S A 93, 12008-12013.
8. Burnstock G (1981). Neurotransmitters and trophic factors in the autonomic nervous system (Review lecture). J Physiol 313, 1-35.
9. Choi S, Park DY, Yeum CH, Chang IY, You HJ, Park CG, Kim MY, Kong ID, So I, Kim KW & Jun JY (2006). Bradykinin modulates pacemaker currents through bradykinin B2 receptors in cultured interstitial cells of Cajal from the murine small intestine. Br J Pharmacol 148, 918-926.
10. Daniel EE & Posey-Daniel V (1984). Neuromuscular structures in opossum esophagus: Role of interstitial cells of Cajal. Am J Physiol 246, G305-G315.
11. Epperson A, Hatton WJ, Callaghan B, Doherty P, Walker RL, Sanders KM, Ward SM & Horowitz B (2000). Molecular components expressed in cultured and freshly isolated interstitial cells of Cajal. Am J Physiol Cell Physiol 279, C529-C539.
12. Gabella G (1979). Innervation of the gastrointestinal tract. Int Rev Cytol 59, 130-187.
13. Gabella G (1995). The structural relations between nerve fibres and muscle cells in the urinary bladder of the rat. J Neurocytol 24, 159-187.
14. Grady EF, Baluk P, Bohm S, Gamp PD, Wong H, Payan DG, Ansel J, Portbury AL, Furness JB, McDonald DM & Bunnett NW (1996). Characterization of antisera specific to NK1, NK2, and NK3 neurokinin receptors and their utilization to localize receptors in the rat gastrointestinal tract. J Neurosci 16, 6975-6986.
15. Hirst GDS, Dickens EJ & Edwards FR (2002). Pacemaker shift in the gastric antrum of guinea-pigs produced by excitatory vagal stimulation involves intramuscular interstitial cells. J Physiol 541, 917-928.
16. Horiguchi K, Sanders KM & Ward SM (2003). Enteric motor neurons form synaptic-like junctions with interstitial cells of Cajal in the canine gastric antrum. Cell Tissue Res 311, 299-313.
17. Horiguchi K, Semple GS, Sanders KM & Ward SM (2001). Distribution of pacemaker function through the tunica muscularis of the canine gastric antrum. J Physiol 537, 237-250.
18. Huizinga JD, Thuneberg L, Kluppel M, Malysz J, Mikkelsen HB & Bernstein A (1995). W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature 373, 347-349.
19. Kennedy MB (2000). Signal-processing machines at the postsynaptic density. Science 290, 750-754.
20. Lavin ST, Southwell BR, Murphy R, Jenkinson KM & Furness JB (1998). Activation of neurokinin 1 receptors on interstitial cells of Cajal of the guinea-pig small intestine by substance P. Histochem Cell Biol 110, 263-271.
21. Luff SE, McLachlan EM & Hirst GD (1987). An ultrastructural analysis of the sympathetic neuromuscular junctions on arterioles of the submucosa of the guinea pig ileum. J Comp Neurol 257, 578-594.
22. 2+-dependent triggering of neurotransmitter exocytosis. Proc Natl Acad Sci U S A 93, 10471-10476.
23. Mitsui R & Komuro T (2002). Direct and indirect innervation of smooth muscle cells of rat stomach, with special reference to the interstitial cells of Cajal. Cell Tissue Res 309, 219-227.
24. Nirasawa Y, Ito Y, Seki N & Akagawa K (1997). HPC-1/syntaxin-1A activity in the enteric nervous system of developing rat gastrointestinal tract. J Smooth Muscle Res 33, 61-66.
25. Patterson LM, Zheng H, Ward SM & Berthoud HR (2001). Immunohistochemical identification of cholecystokinin A receptors on interstitial cells of Cajal, smooth muscle, and enteric neurons in rat pylorus. Cell Tissue Res 305, 11-23.
26. Porcher C, Horowitz B, Bayguinov O, Ward SM & Sanders KM (2002). Constitutive expression and function of cyclooxygenase-2 in murine gastric muscles. Gastroenterology 122, 1442-1454.
27. Portbury AL, Furness JB, Young HM, Southwell BR & Vigna SR (1996). Localisation of NK1 receptor immunoreactivity to neurons and interstitial cells of the guinea-pig gastrointestinal tract. J Comp Neurol 367, 342-351.
28. Roman C, Gonella J, Niel JP, Condamin M & Miolan JP (1975). Effets de la stimulation vagale et de L'adrenaline sur la musculeuse lisse du bas oesophage du chat. INSERM 50, 415-422.
29. Ruegg MA (2001). Molecules involved in the formation of synaptic connections in muscle and brain. Matrix Biol 20, 3-12.
30. Salmhofer H, Neuhuber WL, Ruth P, Huber A, Russwurm M & Allescher HD (2001). Pivotal role of the interstitial cells of Cajal in the nitric oxide signaling pathway of rat small intestine. Morphological evidence. Cell Tissue Res 305, 331-340.
31. Sanmarti-Vila L, tom Dieck S, Richter K, Altrock W, Zhang L, Volknandt W, Zimmermann H, Garner CC, Gundelfinger ED & Dresbach T (2000). Membrane association of presynaptic cytomatrix protein bassoon. Biochem Biophys Res Commun 275, 43-46.
32. Shuttleworth CW, Xue C, Ward SM, de Vent J & Sanders KM (1993). Immunohistochemical localization of 3′,5′-cyclic guanosine monophosphate in the canine proximal colon: Responses to nitric oxide and electrical stimulation of enteric inhibitory neurons. Neuroscience 56, 513-522.
33. Smith TK, Reed JB & Sanders KM (1987). Origin and propagation of electrical slow waves in circular muscle of canine proximal colon. Am J Physiol 252, C215-C224.
34. Song G, Hirst GDS, Sanders KM & Ward SM (2005a). Regional variation in ICC distribution, pacemaking activity and neural responses in the longitudinal muscle of the murine stomach. J Physiol 564, 523-540.
35. Song G, McKee JD, Dixon RE, Spencer EAH, Sanders KM & Ward SM (2005b). Neurokinin neural responses are preserved in the absence of ICC-IM in the stomach. Neurogastro Mot 17 (Suppl. 2), 6-7.
36. Sternini C, Su D, Gamp PD & Bunnett NW (1995). Cellular sites of expression of the neurokinin-1 receptor in the rat gastrointestinal tract. J Comp Neurol 358, 531-540.
37. Sternini C, Wong H, Wu SV, de Giorgio R, Yang M, Reeve J Jr, Brecha NC & Walsh JH (1997). Somatostatin 2A receptor is expressed by enteric neurons, and by interstitial cells of Cajal and enterochromaffin-like cells of the gastrointestinal tract. J Comp Neurol 386, 396-408.
38. Sudhof TC & Rizo J (1996). Synaptotagmins: C2-domain proteins that regulate membrane traffic. Neuron 17, 379-388.
39. Suzuki H & Hirst GDS (1999). Regenerative potentials evoked in circular smooth muscle of the antral region of guinea-pig stomach. J Physiol 517, 563-573.
40. Suzuki H, Ward SM, Bayguinov YR, Edwards FR & Hirst GDS (2003). Involvement of intramuscular interstitial cells in nitrergic inhibition in the mouse gastric antrum. J Physiol 546, 751-763.
41. Thuneberg L (1989). Interstitial cells of Cajal. In Handbook of Physiology: The Gastrointestinal System, Vol. 1, ed. Wood JD, pp. 349-386. American Physiological Society, Bethesda, MD.
42. Torihashi S, Kobayashi S, Gerthoffer WT & Sanders KM (1993). Interstitial cells in deep muscular plexus of canine small intestine may be specialized smooth muscle cells. Am J Physiol 265, G638-G645.
43. Torihashi S, Ward SM, Nishikawa S-I, Nishi K, Kobayashi S & Sanders KM (1995). c-kit-dependent development of interstitial cells and electrical activity in the murine gastrointestinal tract. Cell Tiss Res 280, 97-111.
44. Vannucchi MG, De Giorgio R & Faussone-Pellegrini MS (1997). NK1 receptor expression in the interstitial cells of Cajal and neurons and tachykinins distribution in rat ileum during development. J Comp Neurol 383, 153-162.
45. Wang XY, Sanders KM & Ward SM (1999). Intimate relationship between interstitial cells of Cajal and enteric nerves in the guinea-pig small intestine. Cell Tissue Res 295, 247-256.
46. Wang XY, Sanders KM & Ward SM (2000). Relationship between interstitial cells of Cajal and enteric motor neurons in the murine proximal colon. Cell Tissue Res 302, 331-342.
47. Ward SM, Beckett EAH, Wang X-Y, Baker F, Khoyi M & Sanders KM (2000). Interstitial cells of Cajal mediate cholinergic neurotransmission from enteric motor neurons. J Neurosci 20, 1393-1403.
48. Ward SM, Burns AJ, Torihashi S & Sanders KM (1994). Mutation of the proto-oncogene c-kit blocks development of interstitial cells and electrical rhythmicity in murine intestine. J Physiol 480, 91-97.
49. Ward SM, McLaren GJ & Sanders KM (2006). Interstitial cells of Cajal in the deep muscular plexus mediate enteric motor neurotransmission in the mouse small intestine. J Physiol 573, 147-159.
50. Ward SM, Morris G, Reese L, Wang XY & Sanders KM (1998). Interstitial cells of Cajal mediate enteric inhibitory neurotransmission in the lower esophageal and pyloric sphincters. Gastroenterology 115, 314-329.
51. Won KJ, Sanders KM & Ward SM (2005). Interstitial cells of Cajal mediate mechanosensitive responses in the stomach. Proc Natl Acad Sci U S A 102, 14913-14918.
52. Young HM, McConalogue K, Furness JB & De Vente J (1993). Nitric oxide targets in the guinea-pig intestine identified by induction of cyclic GMP immunoreactivity. Neuroscience 55, 583-596.