Combined effect of cadmium, benzo(a)pyrene and pyrene on the Wistar male rats reproductive system

Trace Elements and Electrolytes

Volumn 23, Issue 4, 2006, Pages 251-257

  Paltanaviciene, A ^a   Zabulyte, D ^a   Kalibatas, J ^a  

^a Institute of Hygiene   (Lithuania)

Author keywords

Benzo(a)pyrene; Cadmium; Combined action; Pyrene; Reproductive system

Indexed keywords

BENZO[A]PYRENE; CADMIUM; PYRENE;

ANIMAL EXPERIMENT; ARTICLE; GENITAL SYSTEM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SPERMATOZOON; TESTIS; TOXICITY; WEIGHT;

EID: 33750391528     PISSN: 09462104     EISSN: None     Source Type: Journal    
DOI: 10.5414/tep23251     Document Type: Article

References (21)

1. Chen L, Ren W, Zhu S, Gao W, Zhou J, Jiang Y, Gu Y. Effects of chronic cadmium loading on the testis and endocrine function of reproduction in male rats. Sheng Li Xue Bao. 2002; 54: 258-262.
2. Damek-Poprawa M, Sawicka-Kapusta K. Damage to the liver, kidney, and testis with reference to burden of heavy metals in yellow-necked mice from areas around steelworks and zinc smelters in Poland. Toxicology. 2002; 186: 1-10.
3. Dudley R, Gammal L, Klaassen C. Cadmium-induced hepatic and renal injury in chronically exposed rats: likely role of hepatic cadmium-metallothionein in nephrotoxicity. Toxicol Appl Pharmacol. 1985; 77: 26-414.
4. Gunnarsson D, Nordberg G, Lundgren P, Selstam G. Cadmium-induced decrement of the LH receptor expression and cAMP levels in the testis of rats. Toxicology. 2003; 183: 57-63.
5. Hellman B. Basic toxicology. In: Waldron HA, Edling C (eds). Occupational health practice. Oxford: Butterworth-Heinemann; 2003. p. 18-34.
6. Inyang F, Ramesh A, Kopsombut P, Niaz M, Hood D, Nyanda A, Archibong A. Disruption of testicular steroidogenesis and epididymal function by inhaled benzo(a)pyrene. Reprod Toxicol. 2003; 17: 527-537.
7. Iscan M, Ada A, Coban T, Kapucuoglu N, Aydin A, Isimer A. Combined effects of cadmium and nickel on testicular xenobiotic metabolizing enzymes in rats. Biol Trace Elem Res. 2002; 89: 177-190.
8. Li J, Yi J, Wang C, Xu P. Effect of cadmium on apoptosis of spermatogenic cells of rat testis and the protection effect of zinc against it. Wei Sheng Yan Jiu. 2000; 29: 135-137.
9. OECD. Guideline for the testing of chemicals. Paris; OECD; 1993. p. 407-408.
10. Paltanaviciene A, Zabulyte D, Jatuliene N. Combined subchronic oral and one-generation reproduction toxicity studies of the cadmium and benzo(a)pyrene complex. Baltic J Lab Anim Sci. 2002; 12: 84-90.
11. Raychoudhury S, Kubinski D. Polycyclic aromatic hydrocarbon-induced cytotoxicity in cultured rat Sertoli cells involves differential apoptotic response. Environ Health Perspect. 2003; 111: 33-38.
12. Ren X, Zhou Y, Zhang J, Feng W, Jiano B. Expression of metallothionein gene at different time in testicular interstitial cells and liver of rats treated with cadmium. World J Gastroenterol. 2003; 9: 1554-1558.
13. Revel A, Raanani H, Younglai E, Xu J, Han R, Savouret J, Casper R. Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects sperm from DNA damage and apoptosis caused by benzo(a)pyrene. Reprod Toxicol. 2001; 15: 479-486.
14. Rodriguez-Ariza A, Dorado G, Navas J. Promutagen activation by fish liver as a biomarker of littoral pollution. Environmental Mol Mutag. 1994; 24: 116-123.
15. Swiergosz R, Zakrzewska M, Sawicka-Kapusta K, Bacia K, Janowska I. Accumulation of cadmium in and its effect on bank vole tissues after chronic exposure. Ecotoxicol Environ Saf. 1998; 41: 130-136.
16. Thomas J. Testes-specific metal toxicology. In: Goyer R, Waalkes M, Klassen C (eds). Organ-specific metal toxicology. Burlington, MA: Academic Press; 1995. p. 98-114.
17. US Department of Health and Human Services. Toxicological profile for polycyclic aromatic hydrocarbons (PAHS). Atlanta, GA: Agency for Toxid Substances and Disease Registry; 1995.
18. US Department of Health and Human Services. Toxicological profile for cadmium. Atlanta, GA: Agency for Toxid Substances and Disease Registry; 1997.
19. WHO. Environmental health criteria. 134: Cadmium. Geneva: WHO; 1992.
20. WHO. Environmental health criteria. Selected non-heterocyclic polycyclic aromatic hydrocarbons. Geneva, WHO; 1998.
21. Yang J, Arnush M, Chen Q, Wu X, Pang B, Jiang X. Cadmium-induced damage to primary cultures of rat Leydig cells. Reprod Toxicol. 2003; 17: 553-560.