Immune system computation and the immunological homunculus

Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)

Volumn 4199 LNCS, Issue , 2006, Pages 499-512

  Cohen, Irun R ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33750379819     PISSN: 03029743     EISSN: 16113349     Source Type: Book Series    
DOI: 10.1007/11880240_35     Document Type: Conference Paper

References (23)

1. Herkel J, Kam N, Erez N, Mimran A, Heifetz A, Eisenstein M, Rotter V, Cohen IR. "Monoclonal antibody to a DNA-binding domain of p53 mimics charge structure of DNA: anti-idiotypes to the anti-p53 antibody are anti-DNA." Eur J Immunol. 2004 Dec; 34(12):3623-32.
2. Efroni S, Harel D, Cohen IR. "Toward rigorous comprehension of biological complexity: modeling, execution, and visualization of thymic T-cell maturation." Genome Res. 2003 Nov;13(11):2485-97.
3. Efroni S, Harel D, Cohen IR. "Reactive animation: Realistic Modeling of Complex Dynamic Systems." 2005 Computer 38:(1):38-47.
4. Efoni S, Harel D, Cohen IR. "A theory for complex systems: reactive animation." in Multidisciplinary Approaches to Theory in Medicine. Studies in Multidisciplinarity, Vol. 3. Ray Paton and Laura McNamara (Editors). Elsevier, Amsterdam. 2005. pp 309-324.
5. Swerdlin N, Cohen IR, and Harel D. "Towards an in-silico Lymph Node: A Realistic Approach to Modeling Dynamic Behavior of Lymphocytes." Submitted for publication.
6. Wikipedia; http://en.wikipedia.org/wiki/Immune_system: "The immune system is the system of specialized cells and organs that protect an organism from outside biological influences."
7. Efroni S, Cohen IR. "The heuristics of biologic theory: the case of self-nonself discrimination." Cell Immunol. 2003; 223(1): 87-89.
8. Cohen IR. "Discrimination and dialogue in the immune system." Semin Immunol 2000; 12(3):215-9; 321-323.
9. Cohen IR. Tending Adam's Garden: Evolving the Cognitive Immune Self. Academic Press, London, UK. 2000.
10. Tauber AI. "Metchnikoff and the phagocytosis theory." Nature Reviews 2003; 4:897-901.
11. Kuhn TS. The Structure of Scientific Revolutions, Second Edition, Enlarged. The University of Chicago Press, Chicago, 1970.
12. Cohen IR. "The cognitive principle challenges clonal selection." Immunol Today 1992; 13(11):441-4.
13. Cohen IR. "Kadishman's Tree, Escher's Angels, and the Immunological Homunculus." Autoimmunity: Physiology and Disease, eds. Coutinho A, Kazatchkine MD. Wiley-Liss, Inc.1994 pp7-18.
14. Harel D and Pnueli A. "On the development of reactive systems." Logics and Models of Concurrent Systems, Apt KR, ed., NATO Advanced Science Institute Series, vol. F-13, Springer-Verlag, 1985, pp. 477-498.
15. Cohen IR, Allan H. "Limits to genetic explanations impose limits on the human genome project." In Encyclopedia of the Human Genome, Nature Publishing Group, Macmillan, 2002.
16. Cohen IR, Hershberg U, Solomon S. "Antigen-receptor degeneracy and immunological paradigms." Molecular Immunology 2004; 40: 993-6.
17. Quintana FJ, Cohen IR. "Heat shock proteins as endogenous adjuvants in sterile and septic inflammation." J Immunol. 2005 1;175(5):2777-82.
18. Cohen IR, Harel D. "Explaining a Complex Living System: Dynamics, Multi-scaling and Emergence." Submitted for publication.
19. Cohen IR. "The cognitive paradigm and the immunological homunculus." Immunol Today 1992; 13(12):490-4.
20. Cohen IR. "Natural Id-Anti-Id Networks and the Immunological Homunculus," in Theories of Immune Networks eds. Atlan H, Cohen IR. Springer-Verlag. (Berlin), 1989; pp 6-12.
21. Cohen IR. "Informational landscapes in art, science, and evolution." Bulletin of Mathematical Biology. 2006. [E-pub ahead of print].
22. Quintana FJ, Hagedorn PH, Elizur G, Merbl Y, Domany E, Cohen IR. "Functional immunomics: microarray analysis of IgG autoantibody repertoires predicts the future response of mice to induced diabetes." Proc Natl Acad Sci U S A., 2004 Oct 5;101: Suppl 2:14615-21. Epub2004 Aug 12.
23. Harel D. "A grand challenge for computing: Full reactive modeling of a multi-cellular animal." Bull European Assoc Theoretical Science, no. 81, Oct. 2003, pp. 226-235.